Clinical trials: Sensorimotor Disorder
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology
Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
Clinical Trial of SB-509 in Subjects With Diabetic Neuropathy
The purpose of the study is to evaluate the clinical effects of the investigational drug, SB-509, in subjects with diabetic neuropathy.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Polyneuropathy
- Trial name
- NCT01079325
- Testing
- SB-509, Saline
- Where
- 31 sites in United States
- Volunteers
- 170 people
- Sponsor
- Sangamo Therapeutics
Polyneuropathy, Charcot Marie Tooth Disease (CMT)
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and…
- Trial name
- PNP (NCT07152197)
- Testing
- Progressive Resistance Exercise Training
- Where
- 2 sites in Chile
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universidad de La Frontera
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Healthy Individuals (Controls), Parkinson Disease
Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices
The goal of this clinical trial is to investigate motor responses in healthy subjects and patients with movement disorders, brain and spinal cord injury, neuromuscular diseases, or cardiovascular diseases.
- Conditions
- Healthy Individuals (Controls), Parkinson Disease, Multiple Sclerosis, Alzheimer Disease
- Trial name
- Allena-mente (NCT07066137)
- Testing
- CAREN, Control group
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Neck Pain, Chronic Neck Pain
Effect of Added Load on Map-Based Proprioceptive Training in Chronic Neck Pain
The purpose of this study is to find out whether adding an external load to a map-based cervical proprioceptive training program provides additional benefit for people with chronic neck pain.
- Trial name
- NCT07900295
- Testing
- Weightless map-based proprioceptive training, Weighted map-based proprioceptive training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Measurement Properties of 5iTUG, Physical Disability
Evaluation of the Measurement Properties of a 5 Time Repeated Instrumented Timed Up and Go (5iTUG)
In order to tailor interventions, objective assessments of physical function is needed. A limitation of several of today's clinical assessments is that they require too much time and/or space.
- Conditions
- Measurement Properties of 5iTUG, Physical Disability, Balance, Cognitive Impairment
- Trial name
- 5iTUG (NCT03769220)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF)
Children With Autism Spectrum Disorder, Typical Developed Children
Investigating Handwriting Characteristics and Underlying Factor in Children With Autism Spectrum Disorder
The mechanism of the motor problem in children with autism spectrum disorder (ASD) in handwriting has been investigated in the following three aspects, including collecting dynamic handwriting performance, exploring the related…
- Trial name
- NCT06228885
- Testing
- handwriting experiment and motor ability test
- Where
- Taiwan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Achalasia
Sensorimotor Dysfunction in Achalasia
This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand and help direct the treatment for patients with achalasia.
- Trial name
- NCT02434991
- Testing
- Barostat
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Tobacco Use Disorder, Schizophrenia
Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia
The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related…
- Trial name
- NCT01213524
- Testing
- sensorimotor replacement, 42 mg transdermal nicotine replacement, usual brand smoking
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Brown University
Stroke
Evaluation of Sensorimotor Ankle Impairments in Chronic Stroke
The purpose of this study is to capture sensorimotor ankle function in a chronic stroke population through validation of novel, experimental metrics and their comparison with established, clinical measures of function.
- Trial name
- NCT06410989
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
No Condition, Healthy Females
Empowering Postpartum Health Through Exercise
The goal of this randomized controlled clinical trial is to investigate the multidimensional recovery process in postpartum women, with particular focus on body image perception, postural alignment, psychological well-being, and…
- Trial name
- EMPOWEX (NCT07595380)
- Testing
- SENSOMOTOR training, Resistance Training
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Rome Foro Italico
Multiple Sclerosis
Effects Of Motor Imagery and Sensorimotor Training
Many types of pain can occur in Multiple Sclerosis (MS), one of the most common types is neuropathic pain. Neuropathic pain is directly related to the disease's demyelination process and is associated with dysesthetic pain…
- Trial name
- MS-MI-SM (NCT07710742)
- Testing
- Motor imagery, Sensorimotor Training, Conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Uludag University
Spinal Cord Injuries, Neuromodulation
Harnessing Neuroplasticity of Postural Sensorimotor Networks Using Non-Invasive Spinal Neuromodulation to Maximize Functional Recovery After Spinal Cord Injury
It has been demonstrated that the human lumbosacral spinal cord can be neuromodulated with epidural (ESS) and transcutaneous (TSS) spinal cord stimulation to enable recovery of standing and volitional control of the lower limbs…
- Trial name
- NCT06213012
- Testing
- Transcutaneous Spinal cord Stimulation, Epidural Spinal Stimulation (ESS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Methodist Hospital Research Institute
Dystonia
Cerebellum and Cortical Plasticity: the Case of Dystonia
Purpose Objective : Sensorimotor adaptation allows the modification of the motor command taking into account the errors detected during execution of prior movements. It involves a large cortico-subcortical network.
- Trial name
- CERDYS (NCT01272154)
- Testing
- Transcranial magnetic stimulation
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
Cortical Lesions in Patients With Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune disease, leading to inflammation and degeneration of neurons in the entire central nervous system (CNS).
- Conditions
- Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Secondary Progressive
- Trial name
- CLiMS (NCT03653585)
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Parkinson's Disease
Stability and Balance in Locomotion Through Exercise
Persons with Morbus Parkinson commonly develop gait and balance disorders leading to dependence, loss of mobility and a high risk of falling.
- Trial name
- StaBLE (NCT01856244)
- Testing
- treadmill walking, Treadmill
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- University of Erlangen-Nürnberg
Concussion, Mild, Sport Injury
Sensorimotor Training for Injury Prevention in Collegiate Soccer Players II
The purpose of this project is to evaluate the effectiveness of an injury prevention intervention delivered primarily using headset virtual reality for collegiate soccer players.
- Trial name
- NCT04036916
- Testing
- Virtual Reality Sensorimotor Training
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of Mississippi Medical Center
Sciatica Pain, Sciatica
Effects of SSMC With and Without Myofascial Release in Patients With Sciatica
Sciatica involves a radiating pain along the sciatic nerve, extending from the lower back through the hips and buttocks to each leg.
- Trial name
- Sciatica (NCT06696898)
- Testing
- Somatosensory Motor Control Exercises, Myofascial Release Technique, Sensorymotor training
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- Riphah International University
Parkinson Disease
Comparative Effects of Virtual Reality and Proprioceptive Neuromuscular Facilitation in Patients With Parkinson's Disease
Parkinson's Disease is a chronic neurodegenerative disorder marked by the progressive loss of dopaminergic neurons in the substantia nigra and accumulation of α-synuclein (Lewy bodies).It impacts both motor and non-motor systems…
- Trial name
- VR PNF RPT PD (NCT07308093)
- Testing
- Intervention 1, artificial intelligence
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Lahore University of Biological and Applied Sciences