Clinical trials: Sensorimotor Disorder
Tetraplegia, Spinal Cord Injury
Cortical Recording and Stimulating Array Brain-Machine Interface
The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.
- Conditions
- Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury
- Trial name
- CRS-BMI (NCT01894802)
- Testing
- Implantation of CRS Arrays
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Michael Boninger
Stroke, Rehabilitation
Augmented-reality Based Mirror Therapy in Stroke Rehabilitation
In the proposed study, the investigators assumed that mirror therapy combined with augmented reality technology will provide a better treatment effects than traditional mirror therapy for the patients with unilateral stroke.
- Conditions
- Stroke, Rehabilitation, Technology, Mirror Movement Therapy
- Trial name
- NCT05580744
- Testing
- Traditional occupational therapy, Mirror therapy using a mirror box, Augmented reality-based mirror therapy
- Where
- Taiwan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
EEG Sleep Spindles, Motor Outcome
Sleep Spindles Organization as an Early Neural Marker of Neuromotor Outcome
The goal of this observational study is to test the effectiveness of quantitative early biomarkers in the sleep electroencephalogram (EEG), namely sleep spindles, as predictors of early sensorimotor maturation and long-term motor…
- Conditions
- EEG Sleep Spindles, Motor Outcome, Cerebral Palsy, SMA1
- Trial name
- SONNO (NCT06256887)
- Where
- 3 sites in Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Spinal Cord Injury, Stroke
Proprioception Testing in Persons With Sensorimotor Impairment
In this study, an FDA-cleared device and type of treatment called "AMES," which stands for Assisted Movement with Enhanced Sensation, will be used to determine whether sensation in the upper limb of individuals with incomplete…
- Conditions
- Spinal Cord Injury, Stroke, Acquired Brain Injury
- Trial name
- NCT01974635
- Testing
- AMES Therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Oregon Health and Science University
Gait Disorder, Sensorimotor, Cognition Disorders
Freezing of Gait and Cognition
The study was aimed to investigate the role of cognition n in FoG.
- Conditions
- Gait Disorder, Sensorimotor, Cognition Disorders, Parkinson Disease
- Trial name
- FOG-As-PD (NCT03477578)
- Testing
- freezers, non freezers
- Where
- Italy
- Volunteers
- 305 people
- Sponsor
- Ospedale Generale Di Zona Moriggia-Pelascini
Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture
Prism Adaptation Therapy for CRPS Type 1
Complex Regional Pain Syndrome (CRPS) is a clinical condition characterized by pain that arises either without an identifiable triggering factor or with a severity disproportionate to the initiating event.
- Conditions
- Complex Regional Pain Syndrome I (CRPS I), Distal Radius Fracture, CRPS (Complex Regional Pain Syndromes), Neuropathic Pain
- Trial name
- NCT07370012
- Testing
- The Prism Adaptation Therapy Group, The Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara Etlik City Hospital
Stroke, Spinal Cord Injuries
Improving Grasp Function in People With Sensorimotor Impairments by Combining Electrical Stimulation With a Robotic Hand Orthosis
Hand motor and sensory impairments resulting from neurological disorders or injuries affect more than 50 million individuals worldwide.
- Conditions
- Stroke, Spinal Cord Injuries, Traumatic Brain Injury
- Trial name
- SENSIBLE-EXO (NCT05976087)
- Testing
- SensoExo
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Andrea Cimolato
Stroke, Chronic Stroke
Reflex Excitability in Post-stroke Stiff-Knee Gait
The purpose of this study is to examine the reflex excitability of the rectus femoris in individuals with and without post-stroke Stiff-Knee gait.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT04947865
- Testing
- Peripheral nerve stimulation, Commercial knee brace
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Post Concussion Syndrome
GyroStim for Post Concussion Syndrome
The goal of this study is to evaluate the efficacy of using sensorimotor multi-axis automated rotational therapy (SMART) to help treat post concussion syndrome (PCS) in adults.
- Trial name
- NCT07527663
- Testing
- Sensorimotor Multi-axis Automated Rotational Therapy (SMART) utilizing GyroStim device, Physical therapy and speech therapy/cognitive rehabilitation therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Neuroscience Group
Hypoxia, Brain, Hypoxia-Ischemia, Brain
Home Stimulation for Brain-Asphyxiated Infants
This study examines the potential benefits of a home stimulation program to treat infants who have suffered from brain asphyxiation (lack of oxygen). The program involves one year of stimulatory activities.
- Trial name
- NCT00006516
- Testing
- Infant stimulation
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cerebral Palsy (CP)
Safety and Tolerability of Dalfampridine in Subjects With Cerebral Palsy
A double-blind, placebo-controlled, crossover study in subjects with cerebral palsy (CP) to evaluate the safety and tolerability and the effect of dalfampridine extended release (ER) tablets on sensorimotor function
- Trial name
- NCT01468350
- Testing
- dalfampridine-ER 10mg
- Where
- 11 sites in United States
- Volunteers
- 35 people
- Sponsor
- Acorda Therapeutics
Postmenopausal Osteoporosis
Effects of Sensorimotor Balance Training vs Digitally Augmented Core Stabilization in Women With Osteoporosis
This randomized controlled trial aims to compare the effects of sensorimotor-based balance training and digitally augmented core stabilization on postural control and fall risk in postmenopausal women with osteoporosis.
- Trial name
- NCT07875894
- Testing
- Sensorimotor-Based Balance Training, Digitally Augmented Core Stabilization
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Schizophrenia, Schizo Affective Disorder
Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia
This application seeks to determine if neurophysiological metrics of memantine (MEM)-enhanced early auditory information processing (EAIP) in schizophrenia (SZ) mediate gains in auditory processing fidelity (APF) and auditory…
- Conditions
- Schizophrenia, Schizo Affective Disorder, Schizoaffective Disorder, Healthy
- Trial name
- NCT03860597
- Testing
- Memantine
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Complex Regional Pain Syndrome Type I of the Upper Limb
Effects of Repetitive Electric Sensory Stimulation (RSS) as Intervention in Complex-regional-pain-syndrome Type I (CRPS)
The purpose of this study is to test a specific nerve stimulation protocol as therapeutic option in patients diagnosed with CRPS (complex regional pain syndrome) of the upper extremity.
- Trial name
- NCT01915329
- Testing
- RSS (repetitive sensory stimulation)
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Ruhr University of Bochum
Cerebral Palsy
Case Series_Targeted Training for Trunk Control Cerebral Palsy
Little is known about how children with cerebral palsy (CP) use their sensory systems (touch, sense of body position, balance organs in the inner ear, vision) to help them achieve trunk control for independent sitting.
- Trial name
- CP_TT_UHart (NCT02246751)
- Testing
- Targeted Training for trunk control
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Hartford
Cerebral Palsy
Assessment of Respiratory Function Cerebral Palsy Using Plyometric Exercise Sensorimotor Program
To examine if adding plyometric exercises to sensorimotor exercises would improve respiratory function in children and adolescents with cerebral palsy
- Trial name
- NCT05506527
- Testing
- Sensorimotor program and plyometric exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Egyptian Chinese University
Diabetic Peripheral Neuropathic Pain (DPN)
NDS and NSS for Screening Diabetic Neuropathy
Diabetic sensorimotor polyneuropathy is a common complication of diabetes mellitus that can lead to pain, sensory loss, foot ulcers, and disability.
- Trial name
- NCT07557641
- Where
- Thailand
- Volunteers
- 228 people
- Sponsor
- Chulalongkorn University
Knee Osteoarthritis, Arthroplasty
Effects of Sensorimotor and Core Stabilization Exercises After Total Knee Arthroplasty
Tha aim of the study is to investigate the effects of core stabilization and sensorimotor exercise program on range of motion, proprioception, balance and functional status in patients with total knee arthroplasty.
- Conditions
- Knee Osteoarthritis, Arthroplasty, Joint Replacement
- Trial name
- NCT05248854
- Testing
- Sensorimotor exercise training, Core stabilization exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Yeditepe University
Stroke, Gait Disorder, Sensorimotor
The Effect of Body Weight Support Treadmill Training on Lower Limb Function in Patients With Chronic Stroke
Stroke has severe debilitating neurological consequences for the victim. Within context of this study, gait disturbance is induced by disabilities in muscle weakness, abnormal muscle contraction, or postural control.
- Trial name
- NCT04491162
- Testing
- Body weight support treadmill training + conventional therapy, Conventional therapy
- Where
- India
- Volunteers
- 36 people
- Sponsor
- National Institute of Mental Health and Neuro Sciences, India
Peripheral Neuropathy, Somatosensory Disorders
Sensorimotor Training for Adults With Diabetic Peripheral Neuropathy
Adults with diabetic peripheral neuropathy tend to fall more frequently than healthy population as a consequence of multiple sensorimotor and cognitive damages.
- Conditions
- Peripheral Neuropathy, Somatosensory Disorders, Sensorimotor Gait Disorder
- Trial name
- NCT05262946
- Testing
- sensorimotor training based on Feldenkrais method, foot care education, usual care
- Volunteers
- 44 people
- Sponsor
- Universidad Complutense de Madrid