Clinical trials: Sensory Modulation Disorder
Shoulder Pain, Healthy Volunteers
Sensory Processing and Musculoskeletal Shoulder Pain
The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the start of their pain treatment.
- Trial name
- NCT05368649
- Testing
- Short-wave diathermy
- Where
- Argentina
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Gran Rosario
Chronic Pain
Clinical Assessment of Pain Processes in Pediatric Patients With Chronic Musculoskeletal Pain
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain during childhood does not only impact physical and psychological aspects of daily life but may…
- Trial name
- MSK (NCT04308044)
- Where
- Canada
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Shriners Hospitals for Children
Epilepsy, Sensory Modulation Disorder
Sensory Modulation in Children With Epilepsy
Epilepsy is a neurological condition that can impact cognitive, motor, and behavioral skills, often leading to sensory modulation disorders (SMDs) in children.
- Trial name
- NCT06818344
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Substance Use Disorders
F-CaST for Individuals With Substance Use Disorder
Examining the effectiveness of the F-CaST based on a controlled randomized trial in patients with SUD residing in a therapeutic community.
- Trial name
- F-CaST (NCT05647863)
- Testing
- Functional Cognitive and Sensory Treatment (F-CaST)
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Tel Aviv University
Brain Diseases
Effects of Sensory Flicker and Electrical Flicker Stimulation
The study will evaluate whether sensory flicker can modulate neural activity of deep brain regions in humans, and whether it can have relevant effects on behavior.
- Trial name
- NCT04188834
- Testing
- Customized version of DAVID device, Blackrock CereStim
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Emory University
Autism
Effects of Qigong Sensory Training on Sensory Modulation and Behavior in Children With Autism
Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition characterized by challenges in social interaction, communication, and a range of repetitive behaviors.
- Trial name
- NCT06893679
- Testing
- Qigong sensory training
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Fibromyalgia (FM), Quantitative Sensory Testing
Investigation of Pain Modulation Phenotypes in Female Patients With Fibromyalgia
Fibromyalgia is characterized by altered pain processing, including impaired descending pain inhibition and central sensitization.
- Conditions
- Fibromyalgia (FM), Quantitative Sensory Testing, Central Sensitization, PRESSURE PAIN THRESHOLD
- Trial name
- NCT07640607
- Testing
- Quantitative Sensory Tests(QST) protocol, Clinical Scales
- Volunteers
- 82 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Fibromyalgia (FM)
Chronic Fibromyalgia Pain, Lifestyle Factors, and Inflammation
The goal of this observational study is to understand how lifestyle factors (such as diet, physical activity, sleep, stress, smoking, and alcohol intake) predict changes in pain sensitivity and modulation in adults aged 18-65…
- Trial name
- BUFS (NCT07074275)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Bournemouth University
Renal Transplantation, Transplant Donation
Effect of a Preoperative Sensory Modulation Room on Pain, Anxiety, and Sleep in Kidney Transplant Patients
The goal of this prospective study is to evaluate whether preoperative exposure to a sensory modulation room can influence postoperative pain, anxiety, and sleep outcomes in adult living kidney donors and recipients.
- Conditions
- Renal Transplantation, Transplant Donation, Donor Nephrectomy
- Trial name
- SMRT-KT (NCT07533669)
- Testing
- Preoperative Sensory Modulation Session
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Nerve Growth Factor, Exercise
Cortical Neuroplasticity by Muscle Pain of Pain-induced Plasticity
The purpose of this study is to investigate the sensory-motor cortical excitability response to delayed onset muscle soreness (DOMS) on Extensor Carpi Radialis (ECR) muscle during muscle hyperalgesia provoked by nerve growth…
- Conditions
- Nerve Growth Factor, Exercise, Motor Activity, Abnormality of SSEPs
- Trial name
- NCT03354624
- Testing
- Sterile solutions of recombinant human nerve growth factor (NGF)
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Osteoarthritis, Fibromyalgia
Assessing Central Aspects of Pain
BACKGROUND: Chronic pain continues for more than 12 weeks despite medication or treatment. Chronic pain is the main symptom of muscle and joint problems, rarely explained by damage to the muscle and joints alone.
- Conditions
- Osteoarthritis, Fibromyalgia, Chronic Low Back Pain, Inflammatory Arthritis
- Trial name
- AsCent (NCT06518278)
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Nottingham
Phantom Limb Pain
Use of Hand Prosthesis With Direct Nerve Stimulation for Treatment of Phantom Limb Pain
Phantom limb pain (PLP) is a frequent consequence of amputation, and it is notoriously difficult to treat. Amputation usually follows traumatic injuries or surgery following vascular diseases, diabetes, osteomyelitis or tumours…
- Trial name
- EPIONE (NCT02796495)
- Testing
- Operation of hand prosthesis with direct nerve stimulation
- Where
- Switzerland
- Sponsor
- Prof. Wassim Raffoul
Stroke
Transcranial Direct Current Stimulation Combined Sensory Modulation Intervention in Chronic Stroke Patients
Background and purpose: About 30% of people with stroke suffered from severe long-term upper extremity （UE） motor impairment. Severe UE impairment, especially dysfunction of hand, can greatly impact stroke patients' daily living…
- Trial name
- NCT01847157
- Testing
- tDCS, Epidermis anesthesia, Repeated passive movement
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Schizophrenia
Pilot Study Using an NMDA Antagonist to Modulate Transcranial Direct Current Stimulation (tDCS) Effects on Sensory Discrimination
Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation which uses a very weak constant current to temporarily excite the brain area of interest via small electrodes placed on the scalp.
- Trial name
- NCT02426983
- Testing
- Direct Current Stimulation, Dextromethorphan
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Stroke, Cerebellum
Imaging Speech in Neurotypical Adults and Individuals With Cerebellar Stroke
The goal of this research study is to learn how the brain areas that plan and control movement interact with the areas responsible for hearing and perceiving speech in healthy adults and people who have had cerebellar strokes.
- Trial name
- NCT06458153
- Testing
- Neural responses to speech functional localizer, Neural responses to silent articulation, Neural responses to self vs. externally generated speech
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Odontalgia
Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls
This project examines experimental pain and chronic pain in the mouth, specifically the condition called atypical odontalgia (AO:atypical toothpain).
- Trial name
- NCT00115102
- Testing
- fentanyl, S-ketamine
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Phantom Limb Pain
Surface Electrical Stimulation for Treatment of Phantom Limb Pain
Phantom limb pain (PLP) is a frequent consequence of amputation, and it is notoriously difficult to treat. Amputation usually follows traumatic injuries or surgery following vascular diseases, diabetes, osteomyelitis or tumours…
- Trial name
- EPIONE (NCT02488668)
- Testing
- Surface Electrical Stimulation
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Winnie Jensen
Adolescent Idiopathic Scoliosis, Cerebral Palsy
Pain Assessment in Children Undergoing Spine Surgery
Musculoskeletal (MSK) pain is one of the most common types of pain among children and adolescents. Recurring episodes of MSK pain conditions have a major impact on the daily lives.
- Trial name
- NCT04244760
- Testing
- Pain assessment for verbal patients, Pain assessment for non-verbal patients
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- Catherine Ferland
Sensory Disorders
Occupational Therapy to Treat Children Who Over or Under React to Their Environment
Children with Sensory Modulation Dysfunction (SMD) either over- or under-react to stimuli in their environment. This can cause significant problems with daily activities and may lead to anxiety, poor attention, low self-esteem…
- Trial name
- NCT00006507
- Testing
- Occupational Therapy
- Where
- United States
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)