Clinical trials: Serotonin Deficiency
Depression - Major Depressive Disorder
Using Fenfluramine to Test the Serotonin Deficiency Theory of Depression
Clinical depression is a common and disabling condition characterised by persistent low mood and loss of interest that interferes with daily functioning.
- Trial name
- FenDep (NCT07651293)
- Testing
- Fenfluramine Hydrochloride, [11C]Cimbi-36
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College Healthcare NHS Trust
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Depression, Serotonin Deficiency
Human Cerebral Blood Flow and Serotonin
Breathing, blood pressure, and blood flow into the brain are controlled - in part - by small areas in the brainstem; the central chemoreceptors.
- Trial name
- NCT05957094
- Testing
- Pharmacological agent: Citalopram
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of British Columbia