Clinical trials: Sessile Serrated Adenoma
Colonic Polyp, Colorectal Polyp
COLO-DETECT: Can an Artificial Intelligence Device Increase Detection of Polyps During Colonoscopy?
COLO-DETECT is a clinical trial to evaluate whether an Artificial Intelligence device ("GI Genius", manufactured by Medtronic) can identify more polyps (pre-cancerous growths of the bowel lining) during colonoscopy (large bowel…
- Conditions
- Colonic Polyp, Colorectal Polyp, Colorectal Adenoma, Colorectal Adenomatous Polyp
- Trial name
- NCT04723758
- Testing
- GI Genius-assisted diagnostic colonoscopy, Diagnostic Colonoscopy
- Where
- 10 sites in United Kingdom
- Volunteers
- 2,032 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Sessile Serrated Adenoma
Use of a Distal Colonoscope Attachment to Increase Detection of Sessile Serrated Adenomas
This study evaluates whether the use of a disposable colonoscope attachment, Endocuff Vision, can increase the detection of sessile serrated adenomas.
- Trial name
- NCT03560037
- Testing
- Endocuff Vision Assisted Colonoscopy
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sessile Serrated Adenoma/Polyps
Usefulness of NBI for Complete Endoscopic Resection of SSA/P
This study is a prospective randomized study to evaluate the role of NBI for improving complete resection rate of sessile serrated adenoma/polyp (SSA/P).
- Trial name
- NCT03761667
- Testing
- Endoscopy using Narrow band imaging
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Soonchunhyang University Hospital
Colorectal Cancer, Colon Adenoma
Risk of Metachronous Findings After Detection of Serrated Lesions and High-grade Dysplasia With Surveillance Delay
The primary aim of this study is to determine the rate of total metachronous advanced neoplasia (TMAN) detection after index detection of serrated lesions (SL) [sessile serrated polyps (SSPs), traditional serrated adenomas…
- Trial name
- SSL follow-up (NCT05355363)
- Testing
- Standard Colonoscopy
- Where
- Canada
- Volunteers
- 727 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Artificial Intelligence
Artificial Intelligence (AI) Assisted Real-time Adenoma Detection and Classification During Colonoscopies
This is a pragmatic, double-blind, randomized, controlled trial, to evaluate the effect of implementing a Computer-assisted detection (CADe) system within the routine clinical practice of Canadian healthcare institutions.
- Trial name
- CAG-SIG-AI (NCT05244278)
- Testing
- Medtronic-GI genius (CADe system for detecting colorectal polyps)
- Where
- Canada
- Volunteers
- 1,596 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Colonic Neoplasms, Colorectal Cancer
Molecular and Histological Characteristics of Serrated Lesions of the Colon
Different subtypes of serrated lesions have been recently described. Among them, both sessile serrated polyp/adenoma (SSP/A) and traditional serrated adenoma (TSA) could have malignant potential through the serrated pathway or…
- Conditions
- Colonic Neoplasms, Colorectal Cancer, Sessile Serrated Adenoma, Polyp of Colon
- Trial name
- SERRACOLON (NCT03089268)
- Testing
- Colonoscopy, Polypectomy or biopsy, Molecular analysis
- Where
- Spain
- Volunteers
- 700 people
- Sponsor
- Hospital Universitario La Fe
Colon Polyps
Prospective Study of Colon Serrated Polyps
With this study, the investigators plan to review the clinical, epidemiology, pathology, and endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of these lesions.
- Trial name
- NCT02332785
- Testing
- Data Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Adenoma, Sessile Serrated Lesion
Evaluation of 'WAYMED Endo CL CS' for Automated Detection and Diagnosis of Colorectal Adenoma and Non-Adenoma Lesions
The purpose of this clinical trial is to evaluate the effectiveness of the computer-aided diagnosis (CADx) software, 'WAYMED endo CL CS', which assists medical specialists by automatically analyzing colorectal endoscopic images…
- Conditions
- Colorectal Adenoma, Sessile Serrated Lesion, Hyperplastic Polyp, Carcinoma
- Trial name
- NCT07470827
- Testing
- WAYMED endo CL CS, Reference standard review
- Where
- South Korea
- Volunteers
- 1,178 people
- Sponsor
- WAYCEN Inc
Colon Adenomas, Colon Polyps
Impact of Computer-aided Detection System on the Right Colon Adenoma Miss Rate
This is a prospective, multicenter randomized controlled trial designed to determine whether the use of computer-aided detection system could reduce the miss rates of adenomas, SSLs, and polyps in the proximal colon during tandem…
- Conditions
- Colon Adenomas, Colon Polyps, Sessile Serrated Lesion
- Trial name
- NCT07308743
- Testing
- Computer-aided detection-assisted colonoscopy, Conventional white-light colonoscopy
- Where
- China
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Colorectal Neoplasms, Colorectal Polyp
MS Versus NICE for Colorectal Lesions
OBJECTIVE: Our study aimed to compare a recently-developed endoscopic classification with an established one for colorectal lesions in a randomised trial between 2013 and 2015.
- Trial name
- NCT02963207
- Testing
- Modified Sano's classification, NICE classification
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Lyell McEwin Hospital
Sessile Colonic Polyp, Serrated Lesion
Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions
The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided…
- Conditions
- Sessile Colonic Polyp, Serrated Lesion, Sessile Serrated Lesion, Colon Adenomas
- Trial name
- NCT07127471
- Testing
- Water exchange with AI-assisted detection, Water exchange with AI-assisted detection and LCI
- Where
- 4 sites in Canada, Italy and 2 more
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Evergreen General Hospital, Taiwan
Adenoma Colon Polyp, Sessile Serrated Adenoma
The Impact of a Colonoscopy Monitoring Program on Endoscopists' Performance
The goal of this clinical trial is to learn if colonoscopy monitoring program works to adenoma detection rate in endoscopists. It will also learn about the impact on sessile serrated lesion detection rate, adenomas per…
- Trial name
- NCT06577610
- Testing
- Feedback from colonoscopy monitoring program
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Adenoma, Sessile Serrated Adenoma
Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions
Texture and Color Enhancement Imaging (TXI) is a newly developed image-enhancing endoscopy technology that has show potential in improving detection of colorectal lesions.
- Trial name
- NCT06515977
- Testing
- TXI (Group A), TXI followed by WLI (Group B), WLI (Group C)
- Volunteers
- 2,964 people
- Sponsor
- Changhai Hospital
Serrated Polyp, Hyperplastic Polyp
Study of Gut Microbiome and Colorectal Tumors
Gut microbiota were assessed in 540 colonoscopy-screened adults by 16S rRNA gene sequencing of stool samples. Investigators compared gut microbiota diversity, overall composition, and normalized taxon abundance among these groups.
- Conditions
- Serrated Polyp, Hyperplastic Polyp, Sessile Serrated Adenoma, Colorectal Cancer
- Trial name
- NCT03297996
- Testing
- Mobio PowerSoil DNA Isolation Kit
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- NYU Langone Health
Adenoma, Colonoscopy
Effect of Two Colonoscopy AI Systems for Colon Polyp Detection
Computer-aided detection (CADe) systems have been actively researched for polyp detection in colonoscopy. The investigators aim to identify the effect of two CADe systems according to the system performance on false positive rate
- Conditions
- Adenoma, Colonoscopy, Sessile Serrated Adenoma
- Trial name
- NCT05089071
- Testing
- Assist by artificial intelligence system for colon polyp detection
- Where
- South Korea
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Colonic Polyp, Colonic Neoplasms
Chromoendoscopy for Serrated Polyposis Syndrome
Serrated polyposis syndrome (SPS) is the most common colorectal polyposis syndrome and is characterized by the combination of large and/or numerous serrated lesions (SLs) throughout the colorectum.
- Conditions
- Colonic Polyp, Colonic Neoplasms, Colonic Cancer
- Trial name
- SERRADA (NCT03476434)
- Testing
- chromoendoscopy with indigo carmine
- Volunteers
- 86 people
- Sponsor
- Hospital Universitario de Móstoles
Adenoma Colon, Serrated Adenoma
Does Inspection of Colonic Mucosa During Insertion Improve Adenoma Detection?
This is a prospective randomised controlled trial to assess an intervention of inspection during both phases of colonoscopic examination ( insertion and withdrawal) improve adenoma detection rate when compared to inspection only…
- Trial name
- INWARD (NCT03254030)
- Testing
- Colonic inspection
- Where
- United Kingdom
- Volunteers
- 490 people
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Cancer, Adenoma
Cold Snare Polypectomy Versus Endoscopic Mucosal Resection for Colonic Sessile Serrated Polyps
Comparing the efficacy of cold snare polypectomy with endoscopic mucosal resection
- Trial name
- CSP-EMR (NCT02967107)
- Testing
- Cold snare polypectomy, Endoscopic mucosal resection
- Where
- Australia
- Volunteers
- 474 people
- Sponsor
- Western Sydney Local Health District
Colorectal Sessile Serrated Adenomas/Polyps
The Real-time Optical Diagnosis Value of Optical Enhancement Endoscopy in Colorectal Sessile Serrated Adenomas/Polyps
When a polyp is found, we begin to wash it and observe it with OE mode 1.Then,the endoscopist gives a real-time optical diagnosis and the future surveillance interval.Finally,the polyp will be resected for the biopsy.
- Trial name
- NCT03238573
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shandong University
Serrated Polyps, Sessile Serrated Adenoma
Study of Narrow Band Imaging in the Characterization of Serrated Lesions
This study is designed to evaluate the utility of Narrow Band Imaging (NBI) compared with High Definition White Light colonoscopy (WLE) in subjects with serrated lesions who do not fulfill the diagnostic criteria of Serrated…
- Conditions
- Serrated Polyps, Sessile Serrated Adenoma, Colorectal Neoplasms
- Trial name
- CROMOSER (NCT02406547)
- Testing
- NBI, WLE
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Parc de Salut Mar