Clinical trials: Sexually Transmitted Infections (STIs)
Hiv, Adolescent Behavior
A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM
This pragmatic trial of an HIV prevention program focuses on HIV risk-reduction in men who have sex with men (MSM) ages 13-18. The design is a three-tiered, internet-based HIV prevention intervention series that uses a sequential…
- Conditions
- Hiv, Adolescent Behavior, Sex, Safe
- Trial name
- SMART (NCT03511131)
- Testing
- Queer Sex Ed, Keep It Up, Keep It Up-Control
- Where
- United States
- Volunteers
- 1,306 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infections, Papillomavirus, Papillomavirus Vaccines
Evaluation of Safety and Immunogenicity of a Human Papillomavirus (HPV) Vaccine in Human Immunodeficiency Virus (HIV) Infected Females
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. This Phase IV, observer-blind study is designed to evaluate the safety and immunogenicity of Cervarix in HIV infected…
- Trial name
- NCT01031069
- Testing
- GSK Biologicals' HPV vaccine 580299, Merck's Human Papillomavirus Quadrivalent (Types 6, 11, 16, and 18) Vaccine (Gardasil)
- Where
- 15 sites in Brazil, Estonia and 2 more
- Volunteers
- 873 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Human Immunodeficiency Virus
A Trial to Assess the Functionality of Female Condom With a Silicone Elastomer Vaginal Ring
A multi-center, open-label, randomized, two-period, crossover non-inferiority trial to assess the functionality of female condoms with a silicone elastomer vaginal ring.
- Trial name
- NCT01755754
- Testing
- Silicone Elastomer Vaginal Ring, Female Condom
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Cervical Cancer, Condylomata Acuminata
Plateau Antibody Levels of a Recombinant (E.Coli) HPV Nonavalent Vaccine Versus Gardasil®9 in Young Women
This study is designed to compare plateau antibody levels of a novel recombinant human papillomavirus vaccine (types 6,11,16,18,31,33,45,52,58 )(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., with Gardasil®9 in females…
- Trial name
- NCT06197802
- Testing
- Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58 )Vaccine(E.Coli), Gardasil®9
- Where
- China
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Xiamen University
Herpes Zoster, Shingles
Bioequivalency Study of Valacyclovir Hydrochloride 1000 mg Under Fasting Conditions
The objective of this study was to prove the bioequivalence of Valacyclovir Hydrochlorothiazide Caplet under fasting conditions.
- Conditions
- Herpes Zoster, Shingles, Genital Herpes
- Trial name
- NCT01132729
- Testing
- Valacyclovir Hydrochloride
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
HIV Infections, Sexually Transmitted Diseases
Evaluation of Many Men, Many Voices, An STD/HIV Prevention Intervention for Black MSM
The purpose of this program evaluation is to determine whether the "Many Men, Many Voices" HIV/STD prevention intervention is effective in reducing HIV sex risk behaviors and increasing HIV testing among African-American men who…
- Trial name
- 3MV (NCT00137631)
- Testing
- Many Men, Many Voices (3MV)
- Where
- United States
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis
STI Prophylaxis and Emergence of Antimicrobial Resistance
The goal of this observational study is to understand the risk of antibiotic resistance and changes in the human microbiome (bacteria that live inside and on us), if people use antibiotics to prevent sexually transmitted…
- Conditions
- Sexually Transmitted Infection (STI) Prevention, Antibiotic Prophylaxis, Antibiotic Resistance, Bacterial, Microbiome
- Trial name
- SPEAR (NCT06778083)
- Where
- United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University College, London
Papillomavirus Infections, Uterine Cervical Neoplasms
HPV Infection and Genital Microecology of Childbearing-age Female in China: A Cohort and Multicenter Study
The purpose of this study to access the relations between genital microecology, HPV infection and cervical intraepithelial neoplasia of childbearing-age female in China
- Conditions
- Papillomavirus Infections, Uterine Cervical Neoplasms, Sexual Transmitted Disease
- Trial name
- NCT04694495
- Testing
- 16S rRNA gene sequencing of cervical secretions
- Where
- 42 sites in China
- Volunteers
- 7,500 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Hiv
Efficacy Trial of Life Simulation Game to Routinize Adolescent HIV Testing
This study will aim to assess the acceptability, usability and efficacy of using state-of-the-art video game technology to increase HIV testing among adolescents and young adults (AYA) ages 13-24.
- Trial name
- NCT04917575
- Testing
- Mobile Game, Mobile Application
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- George Washington University
Papillomavirus Infections
GARDASIL™ Post Marketing Surveillance in the Philippines (V501-077)
This study will collect safety information on the use of GARDASIL™ in the Philippines.
- Trial name
- NCT01355003
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Infections, Papillomavirus
Efficacy Study of HPV-16/18 Vaccine (GSK 580299) to Prevent HPV-16 and/or -18 Cervical Infection in Young Healthy Women
The purpose of this phase IIB MedImmune-sponsored study was to evaluate the efficacy of the HPV-16/18 VLP vaccine in the prevention of infection with HPV-16 and/or HPV-18 in adolescent and young adult women.
- Trial name
- NCT00689741
- Testing
- Cervarix
- Volunteers
- 1,113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Stigma, Social, HIV/AIDS
Transgender Education for Affirmative and Competent HIV and Healthcare
Educational workshops are an efficacious strategy to increase healthcare providers' ability to provide gender-affirming care for transgender (trans) people.
- Conditions
- Stigma, Social, HIV/AIDS, Health Care Acceptability
- Trial name
- TEACHH (NCT04096053)
- Testing
- TEACHH
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Toronto
HIV, Hepatitis C
Behavioral Science Aspects of Rapid Test Acceptance
The relevance of this research to public health is to make it possible to test for hepatitis C and syphilis at point of care so that people will receive their results immediately instead of requiring people to wait for at least a…
- Conditions
- HIV, Hepatitis C, Hepatitis B, Syphilis
- Trial name
- BSARTA (NCT01317784)
- Testing
- Rapid tests for HIV, HCV, HBV, and syphilis, HIV/HCV, HIV/syphilis
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- California State University, Long Beach
Infections, Papillomavirus
Evaluation of the Immune and Safety Response of GlaxoSmithKline (GSK) Biologicals' HPV Vaccine in Healthy Indian Women
Human papillomavirus infection has clearly been recognized as the cause of cervical cancer. Indeed, the infection of the cervix by certain oncogenic types of HPV, if not cleared , can lead over time to cervical cancer in women .
- Trial name
- NCT00344032
- Testing
- HPV-16/18 VLP/AS04 Vaccine (Cervarix TM)
- Where
- 4 sites in India
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HIV Infection
MAPS PrEP Van Study
For this study the investigators aim to see if giving participants an oral HIV prevention medication on a medical van, is a good option of care for individuals who inject drugs and/or are sexually active and therefore at a higher…
- Trial name
- MAPS PrEP (NCT06908252)
- Testing
- Pre-Exposure Prophylaxis (PrEP)
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Duke University
HIV Infections
Cardiovascular Responses to Exercise in People Living With HIV/AIDS: Effects of Exercise Training
Patients living with HIV (PLWHIV) have compromised muscle metaboreflex, which can cause exercise intolerance. This randomized controlled clinical trial will verify the effects of regular exercise on autonomic and hemodynamic…
- Trial name
- NCT04512456
- Testing
- Exercise training
- Where
- Brazil
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cardiologia de Laranjeiras
Human Papillomavirus Infection
Promoting HPV Vaccination Among Young Adults in Texas
This clinical trial studies how to improve the human papillomavirus (HPV) vaccination rate in young adults in Texas. This trial aims to learn more about how researchers and health care providers can increase HPV vaccination among…
- Trial name
- NCT05057312
- Testing
- Enhancing Accessibility to Health Care, Informational Intervention, Interview
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Herpes Simplex
A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes
The purpose of this first-time-in-human (FTiH) study is to evaluate the reactogenicity, safety, immune response, and efficacy of an investigational herpes simplex virus (HSV)-targeted immunotherapy (TI).
- Trial name
- NCT05298254
- Testing
- Non-adjuvanted HSV formulation 1, Non-adjuvanted HSV formulation 2, Non-adjuvanted HSV formulation 3
- Where
- 30 sites in United States, Australia and 6 more
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
HPV Infection
Global Burden Estimation of Human Papillomavirus (GLOBE-HPV)
This study is a multi-country and multi-site project to estimate the point-prevalence of high-risk (HR) HPV genotype infections among representative samples of girls and women aged 9-50 years, and among specific sub-populations…
- Trial name
- HPV (NCT06129253)
- Testing
- Urine Sample Collection, Self-collected Vaginal Swab, Blood Samples
- Where
- 8 sites in Bangladesh, Democratic Republic of the Congo and 6 more
- Volunteers
- 29,750 people, healthy volunteers welcome
- Sponsor
- International Vaccine Institute
HIV Infection, AIDS
Accuracy of the Pima™ CD4 Test for Enumeration of CD4+ T-Cell Counts
This is a multi-center study designed to assess the accuracy of Pima™ CD4 Test to enumerate CD4+ T-cells in whole blood over the measurement range expected for the intended population.
- Conditions
- HIV Infection, AIDS, HIV Infections
- Trial name
- NCT00951795
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott RDx Cardiometabolic
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