Clinical trials: Skeletal Muscle Endurance
Placebo, Tetraselmis Chuii
TetraSOD® Supplementation and Skeletal Muscle Redox Gene Expression
Tetraselmis chuii (TetraSOD) is a marine microalgae that has been reported to improve antioxidant responses in human skeletal muscle cells treated with TetraSOD and to improve recovery from muscle damaging exercise in humans…
- Trial name
- NCT06822556
- Testing
- Tetraselmis chuii
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy
Vitamin D Supplementation in Healthy Adults in Prolonged Endurance Exercise
The purpose of this study is to investigate the effects of vitamin D supplementation on biochemistry response and skeletal muscle synthesis in prolonged endurance exercise.
- Trial name
- NCT05781620
- Testing
- Vitamin D, Medium-chain triglycerides
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Age-related Muscle Decline
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
This Phase 1/2a, open-label, non-randomized study is designed to evaluate the safety and tolerability of intramuscular AAV9-Follistatin gene therapy administered either as monotherapy or in combination with a VEGF-encoding…
- Trial name
- CALM-AF-AI (NCT07443826)
- Testing
- AAV9-Follistatin gene therapy, VEGF Plasmid
- Where
- Honduras
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Unlimited Biotechnology LLC
Elite Cyclists
Predicting the Efficacy of Resistance Exercise Training for Improving Endurance Performance
The overall objective of the study is to identify molecular determinants of the efficacy of resistance training for improving endruance performance in elite cyclists
- Trial name
- IDperform (NCT04637178)
- Testing
- Resistance training, Endurance training (habitual)
- Where
- Norway
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Exercise, Histamine
Influence of Endurance Exercise and Histamine Receptors on the Gene Expression in Skeletal Muscle
Blocking histamine H1/H2 receptors blunts chronic endurance training adaptations. The current study addresses a twofold research question: "What is the influence of endurance training (1) and histamine H1 and H2 signaling (2) on…
- Trial name
- NCT05131555
- Testing
- H1 blockade: H1 receptor antagonist + exercise training, H2 Blockade: H2 receptor antagonist + exercise training
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy Adult, Cyclists
Musculotendinous Adaptations to Strength and Endurance Training in Cyclists
This study investigated whether adding strength training to regular endurance training improves performance and muscle function in competitive cyclists.
- Conditions
- Healthy Adult, Cyclists, Athletes
- Trial name
- STEND (NCT07658300)
- Testing
- Strength training, Endurance training
- Where
- Lithuania
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Lithuanian Sports University
Diet, Healthy, Protein Deficiency
Protein and Performance (PROPER) in Endurance Athletes
The present study is a parallel group design with randomised allocation to either a 1) reduced protein diet (RP) or a 2) normal protein diet (NP).
- Trial name
- PROPER (NCT05426447)
- Testing
- Dietary intervention of reduced protein intake, Dietary intervention of normal protein intake
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Sarcopenia
Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly
The primary objective of this trial is to evaluate the effect of oral administration of an Astaxanthin formulation compared to placebo after one month alone and after an additional 3 months of exercise training on mitochondrial…
- Trial name
- NCT03368872
- Testing
- Astaxanthin formulation, Exercise training
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Astavita, Inc.
Sleep Deprivation, Healthy Volunteers
Effects of Sleep Privation on Sensorimotor Integration of the Upper Limb During a Manual Endurance Test in Healthy Volunteers-Physiological Study
The investigator showed that a night of sleep deprivation halved the duration of an inspiratory endurance test and that this loss of endurance could be secondary to a lack of activation of the pre-motor cortex.
- Conditions
- Sleep Deprivation, Healthy Volunteers, Skeletal Muscle
- Trial name
- NCT03404427
- Testing
- Normal sleep night, Sleepless night
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Healthy, Cyclists
Effects of Including Sprints During Low-intensity Cycling Exercises on Performance and Muscle/Blood Characteristics
To investigate the effects of Including 30-s sprints during low-intensity cycling exercises during a training camp on performance and muscle/blood characterisitcs in elite cyclists
- Trial name
- NCT04640883
- Testing
- Inclusion of sprints during low-intensity cycling during a 14-day training camp (high training load), Low-intensity cycling during a 14-day training camp (high training load), Recovery for 10 days (low training load)
- Where
- Norway
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Exercise
Protein Supplementation and Endurance Exercise Adaptations
Participants will perform three endurance training sessions weekly for 12 weeks. All participants will be randomly assigned to the protein supplementation group or the placebo (iso-caloric carbohydrate) group.
- Trial name
- NCT03462381
- Testing
- Protein
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Ageing, Muscle Fatigue Caused by Repetitive Muscle Exercise
The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction
The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes.
- Trial name
- NCT07090603
- Testing
- Knee extension exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Skeletal Muscle Damage, Muscle Damage
Whey and Soy Protein Supplementation in Football Players
In a constant effort to find ways to make a quicker recovery between demanding workouts and football matches, this study is the first to investigate the benefits of protein supplementation, and compares two types of proteins, an…
- Conditions
- Skeletal Muscle Damage, Muscle Damage, Athletic Performance
- Trial name
- NCT03753321
- Testing
- Whey protein, Soy protein
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Skeletal Muscle Hypertrophy
The Effects of Heavier- and Lighter-load Resistance Training on Arm and Leg Muscle Mass in Young Adult Women
When you perform weightlifting, your body makes new proteins within your muscle. These new proteins can increase the size of the fibers within your muscle to make your muscle larger, a process called hypertrophy.
- Trial name
- FHALL (NCT04547972)
- Testing
- Higher-load resistance training, Lower-load resistance training
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Damage
Effect of Strength Versus Endurance Training on Muscle Damage in Gym Athletes on Caffeine Supplementation.
Dietary supplements to enhance exercise and athletic performance come in a variety of forms, including tablets, capsules, liquids, powders, and bars.
- Trial name
- NCT06086691
- Testing
- Strength Training with Caffeine, Endurance Training with Caffeine
- Where
- Pakistan
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Local Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity
Near-Infrared Spectroscopy, Acute Taurine Supplementation, and Isolated Muscular Endurance and Fatigue Resistance in Young Healthy Adults
The goal of this clinical trial is to determine the association between near-infrared spectroscopy (NIRS)-derived mitochondrial oxidative phosphorylation (OXPHOS) capacity of the vastus lateralis muscles, and both local muscular…
- Conditions
- Local Muscular Endurance and Fatigue, NIRS Skeletal Muscle Mitochondrial Capacity, Acute Taurine Supplementation
- Trial name
- NCT07654946
- Testing
- Acute Taurine Supplementation
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Louisiana State University and A&M College
Skeletal Muscle Endurance
Resistance Exercise Blood Flow Restriction
The number of repetitions able to be performed during resistance exercise is impacted by the load an individual is working against.
- Trial name
- BFRCL (NCT06724458)
- Testing
- Resistance exercise
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Statin Adverse Reaction
Exercise Intensity and Muscle Recovery in Statin Users
This study aims to investigate how different types and intensities of exercise affect muscle recovery in individuals taking statin medications compared to healthy controls.
- Trial name
- STN-EX (NCT07563452)
- Testing
- Dose-Escalation Exercise Protocol
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Raffaele Mazzolari
Heat-suit Endurance Training, Non-heat-suit Endurance Training
Effects of Heat-suit Training on Biological and Performance Characteristics in Elite Cyclists
The overall objective of the study is to investigate the effects of five weeks of heat-suit training on training-associated changes in hemoglobin mass, skeletal muscle characteristics and endurance exercise performance in elite…
- Trial name
- HeatME (NCT04611646)
- Testing
- Heat-suit endurance training, Non-heat-suit endurance training
- Where
- Norway
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Inland Norway University of Applied Sciences
Hypertrophy, Exercise Training
Resistance Training, Detraining, and Retraining Study 2024 (TraDeRe2024)
The goals of our research project are to identify factors explaining inter-individual variation in responses to resistance training (RT) and the baseline determinants underlying an individual's sensitivity to respond to RT.
- Conditions
- Hypertrophy, Exercise Training, Skeletal Muscle Atrophy, Healthy
- Trial name
- TraDeRe (NCT06573086)
- Testing
- Resistance Training
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla