Clinical trials: Skeletal Muscle Hypertrophy
Healthy Volunteers, Muscle Hypertrophy
Glycolytic Phenotype (vLapeak) and Magnitude of Skeletal Muscle Hypertrophy After Resistance Training
The HyperLa study investigates whether a person's "glycolyticness"-the efficiency with which their body uses glycolysis for energy-can predict how much their muscles will grow (hypertrophy) in response to resistance training.
- Conditions
- Healthy Volunteers, Muscle Hypertrophy, Glycolysis, Moderately Trainend
- Trial name
- HyperLa (NCT07721766)
- Testing
- Hypertrophy-focused Resistance Training
- Where
- 8 sites in Finland, Germany and 2 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Investigating the Effects of Power Training in the Elderly
Effects of Different Power Training Intensities in Older Adults
Power (strength × velocity) is a crucial component for maintaining independence during aging. Therefore, investigating interventions aimed at improving this physical capacity is essential for this population.
- Trial name
- NCT07023146
- Testing
- Moderate to high intensity (PTMH; 65-80% of 1-repetition maximum [1RM]) ), low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Skeletal Muscle
Leucine or Protein Supplementation and Resistance Training
The purpose of this study was to determine the effects of L-leucine (LEU) or different protein supplements standardized to LEU (~3.0 g/serving) on changes in body composition, strength, and histological attributes in skeletal…
- Trial name
- MPS (NCT03501628)
- Testing
- L-leucine + maltodextrin, Whey protein concentrate, Hydrolyzed whey protein concentrate
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Auburn University
Muscle Fiber Atrophy, Type II
The Effect of Neuromuscular Electrical Stimulation (NMES)
The purpose of this project is to test the effectiveness of neuromuscular electrical stimulation (NMES) that produces 40 % of maximum voluntary contraction (MVC) in increasing muscle size and improvement in muscle force output…
- Trial name
- NMES (NCT00765739)
- Testing
- Neuromuscular electrical stimulation, voluntary strengthening exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Muscle Hypertrophy, Muscle Strength
Upper Versus Lower Limb Responses to Higher Versus Lower Load Resistance Training in Young Men
Recent research suggests that performing resistance exercise training with relatively light loads is equally as effective at increasing muscle mass and muscle strength as performing resistance exercise training with relatively…
- Trial name
- NCT03993483
- Testing
- Unilateral resistance exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- McMaster University
Muscle Hypertrophy in Healthy Young Men
Chronic Beta2-adrenergic Stimulation and Cardiac and Skeletal Muscle Hypertrophy
Studies in animals have shown that beta2-adrenoceptor activation with selective agonists regulates protein metabolism and muscle growth in skeletal and cardiac muscle tissue.
- Trial name
- NCT02551276
- Testing
- Salbutamol, Resistance training
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Muscle Hypertrophy in Healthy Young Men
Effects of Deloading Periods in Resistance Training on Muscular Strength and Hypertrophy
This study investigates the effects of deloading periods (short breaks or reductions in training volume) in a 8-week resistance training program on muscle strength and hypertrophy in young, untrained individuals.
- Trial name
- DPRT (NCT06825052)
- Testing
- Resistance Training with Deloading Periods, Continuous Resistance Training
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Muscle Hypertrophy, Muscular Strength
Determining the Effect of Shoulder Flexion Angle on Latissimus Dorsi and Forearm Flexor Hypertrophy
The goal of this clinical trial is to learn the effect of training a muscle at a longer or shorter muscle length during resistance exercise in young and healthy adults.
- Trial name
- LPDLR (NCT07360236)
- Testing
- LAT PULLDOWN and LAT ROW training sessions, Maximal isotonic strength testing (1RM), Isokinetic strength testing (1080 Quantum)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Composition, Sarcopenia
Effects of Increased, Egg-Based Protein Intake on Muscle Composition,
This study is designed to assess the effect of a diet-controlled nutrition program utilizing an egg-based higher protein diet on muscle composition and size, and indices of metabolic health and markers of systemic inflammation in…
- Conditions
- Muscle Composition, Sarcopenia, Hypertrophy, Inflammation
- Trial name
- S25 (NCT01396915)
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Purdue University
Delayed Onset Muscle Soreness
The Effect of Low-Intensity Resistance Exercise Training
It was to compare the effect of low-load resistance training with blood flow restriction (LL-BFR) and high-intensity resistance training (HI-RT) on muscle strength, endurance and volume, functional performance, and delayed onset…
- Trial name
- NCT04755608
- Testing
- Low Intensity Exercises with Blood Flow Restriction, High Intensity Resistant Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Muscle Hypertrophy, Muscular Strength
The Effect of Peak Force At Long and Short Muscle Lengths and the Impact on Muscle Growth and Strength
The goal of this clinical trial is to learn the effect of applying peak force/resistance to skeletal muscles during resistance exercise training in young and healthy adults.
- Trial name
- SLML (NCT06666127)
- Testing
- LONG and SHORT Resistance Training, Maximal Isotonic Strength Testing (1RM), Isokinetic Strength Testing
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Muscle Hypotrophy
Assessment of the Efficacy of Carnipure® AAS on Body Composition, Muscle Thickness, and Strength Adaptations in Healthy Men
This study is a 12-week randomized active control trial that is investigating the effects of Carnipure(R) AAS on muscle hypertrophy, body composition, and muscular strength adaptations in healthy men performing a resistance…
- Trial name
- NCT05681806
- Testing
- Carnipure AAS, Creatine Monohydrate
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Muscle Hypertrophy, Strength
Effects of Carbohydrates Versus Carbohydrates + Protein on Resistance Training Outcomes
Higher energy and carbohydrate intakes have been hypothesized to enhance resistance training adaptations, yet empirical evidence remains mixed.
- Trial name
- CHO & PRO+CHO (NCT07600138)
- Testing
- CHO, PRO
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Auburn University
Athletic Performance, Muscle Strength
Comparison of Velocity-Based and Traditional Strength Training in Youth Soccer Players
This study compared the effects of velocity-based strength training and traditional strength training on physical performance and muscle adaptations in youth soccer players.
- Conditions
- Athletic Performance, Muscle Strength, Resistance Training
- Trial name
- NCT07447258
- Testing
- Velocity-Based Training (10% Velocity Loss), Velocity-Based Training (20% Velocity Loss), Traditional Strength Training
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Engin Güneş Atabaş
Smartphone Addiction, Masseter Muscle Hypertrophy
Investigating the Effects of Smartphone Use on the Masseter Muscle
The aim of this study was to determine the short- and long-term effects of smartphone use on the masseter muscle. In the short term, to investigate whether repetitive thumb movements during phone use will cause a spontaneous…
- Conditions
- Smartphone Addiction, Masseter Muscle Hypertrophy, Masseter Muscle Spasm
- Trial name
- NCT06408766
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Muscle Hypertrophy, Muscle Fibre Activation
Lower and Higher Load Resistance Exercise Protocols: Acute Muscle Activation and Skeletal Muscle Hypertrophy
How much weight an individual lifts per workout does not dictate the relative increase in muscle size the individual gains following weeks of training, which is contrary to current strength training dogma.
- Trial name
- NCT03991117
- Testing
- resistance exercise
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- McMaster University
Healthy
Salmeterol Effect on Exercise Performance
The purpose of the project is to investigate the muscle anabolic response to acute beta2-adrenergic stimulation in young healthy men and women.
- Trial name
- NCT06655012
- Testing
- Salmeterol
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Physical Activity
The Impact of Exercise With Blood Flow Restriction: Sex and Age Differences
The primary objective is to investigate whether six weeks of resistance training, in combination with blood flow restriction, produces a different adaptation in fat-free mass between males and females that are not physically…
- Trial name
- NCT05615831
- Testing
- Resistance Training with Blood flow restriction
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick
Exercise Training, Healthy
Why do People Respond Differently to Resistance Training?
It is well known that regular resistance training (RT) can have health benefits. However, considerable heterogeneity in RT responses has been observed.
- Conditions
- Exercise Training, Healthy, Skeletal Muscle Hypertrophy
- Trial name
- PreEx (NCT05874986)
- Testing
- Resistance training
- Where
- Finland
- Volunteers
- 393 people, healthy volunteers welcome
- Sponsor
- University of Jyvaskyla
Muscle Hypertrophy
Low-Load BFR vs. High-Load Training on Biceps Hypertrophy
This study aimed to compare the effects of low-load blood flow restriction resistance exercise (BFR-RE) performed to voluntary failure with traditional high-load resistance exercise (HL-RE) and a control condition on biceps…
- Trial name
- NCT07561281
- Testing
- Blood Flow Restriction Resistance Exercise, High-Load Resistance Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University