Clinical trials: Skin, open to volunteers
Facial Skin Laxity
VISION Study: Visualization-Guided SMAS Treatment to Optimize Nonsurgical Lifting
The VISION study is a prospective, randomized, single-center, split-face Phase IV clinical trial evaluating whether customized multi-depth microfocused ultrasound with visualization (Ultherapy PRIME) targeting the…
- Trial name
- NCT07890987
- Testing
- Microfocused Ultrasound with Visualization (MFU-V), multi Microfocused Ultrasound with Visualization (MFU-V)
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ocean Clinic
Melanoma (Skin Cancer), HER2-low Hormone Receptor Positive Breast Cancer
Study of AMXT 1501 and DFMO in Combination With Standard Therapies in Advanced Solid Tumors
This study will evaluate the safety, tolerability, and preliminary effectiveness of AMXT 1501 and DFMO when combined with standard treatments for advanced solid tumors.
- Trial name
- NCT07287917
- Testing
- AMXT 1501 Dicaprate, DFMO, Fulvestrant
- Where
- 20 sites in United States
- Volunteers
- 92 people
- Sponsor
- Aminex Therapeutics, Inc.
Penis/Surgery, Penis/Injuries
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
The goal of this randomized interventional clinical trial is to learn if placement of a thin layer of fatty tissue (fat graft) beneath a split-thickness skin graft on the surface of the penis improved outcomes of surgery in men…
- Conditions
- Penis/Surgery, Penis/Injuries, Penile Skin, Adult-Acquired Buried Penis
- Trial name
- NCT07316491
- Testing
- Autologous fat grafting, Genitourinary Reconstruction with Split-Thickness Skin Grafting
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Atopic Dermatitis
A Study to Learn About the Study Medicine Called Tilrekimig in People With Moderate-to Severe Eczema
The purpose of this study is to find out how well tilrekimig works, how safe it is, and how it affects the body in adults and adolescents with moderate to severe atopic dermatitis (eczema).
- Trial name
- Tilrek (NCT07783425)
- Testing
- Tilrekimig, Dupilumab
- Where
- 32 sites in United States, Japan
- Volunteers
- 1,375 people
- Sponsor
- Pfizer
Skin Graft Donor Site, Wound Healing
Autologous Skin Cell Suspension (RECELL®) for Accelerated Healing of Split-Thickness Skin Graft Donor Sites: A Randomized, Intra-Patient (Split-Site) Controlled Trial
This study evaluates whether applying RECELL® autologous skin cell suspension (ASCS) to one half of a split-thickness skin graft (STSG) donor site accelerates re-epithelialization and improves long-term scar quality compared with…
- Conditions
- Skin Graft Donor Site, Wound Healing, Split-Thickness Skin Graft
- Trial name
- RECELL®-STSG (NCT07888166)
- Testing
- RECELL® Autologous Cell Harvesting Device, Standard Transparent Film Dressing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Fine Lines and Wrinkles, Skin Health
Efficacy of an LED Mask
The goal of this interventional study is to evaluate the efficacy and perception a commercial LED device in 110 healthy adult females and males between the ages of 35-65 years old, inclusively.
- Conditions
- Fine Lines and Wrinkles, Skin Health, Skin Tone
- Trial name
- NCT07890233
- Testing
- Light emitting diode treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Therabody, Inc.
Malignant Melanoma of Skin, Other and Unspecified Malignant Neoplasm of Skin
Using an Artificial Intelligence (AI) Tool for Melanoma Diagnosis
The purpose of this study is to learn whether a computer-based support tool called DEXI (Dermoscopy EXplainable Intelligence) can help dermatologists decide whether a lesion may be melanoma, a serious type of skin cancer.
- Conditions
- Malignant Melanoma of Skin, Other and Unspecified Malignant Neoplasm of Skin, Melanoma in Situ, Carcinoma in Situ of Skin
- Trial name
- NCT07890415
- Testing
- Clinical decision support tool
- Where
- 8 sites in United States
- Volunteers
- 14,000 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Frequency and Type of Medical Adhesive-Related Skin Injury, NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate)
Evaluation of a Switchable Acrylic Adhesive Drape for Safer Removal in Negative Pressure Wound Therapy Applications.
Negative pressure wound therapy (NPWT) is widely used for chronic and acute wounds, severe burns, and post-operative care. Despite its benefits, the strong adhesive required to maintain an airtight seal increases the risk of…
- Conditions
- Frequency and Type of Medical Adhesive-Related Skin Injury, NPWT Drape Seal Effectiveness Rate (or Leak Incidence Rate), Clinician Acceptability of New NPWT Drape, Patient Drop-out Rate From Prescribed NPWT Treatment
- Trial name
- NCT06717308
- Testing
- Comfort Release® NPWT drape
- Where
- 7 sites in United States
- Volunteers
- 300 people
- Sponsor
- Global Biomedical Technologies, LLC
Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative
Intratumoral N17350 in Advanced Solid Tumors
The goal of this clinical trial is to learn if N17350 works to treat advanced solid tumors in adults. It will also learn about the safety of N17350 and help determine the best dose to use in future studies.
- Conditions
- Neoplasms, Solid Tumor, Breast Neoplasms, Triple-Negative, Squamous Cell Carcinoma of Skin, Melanoma
- Trial name
- OP-NEU-101 (NCT07339176)
- Testing
- N17350
- Where
- 9 sites in United States, Australia
- Volunteers
- 275 people
- Sponsor
- Onchilles Pharma Inc
Skin Aging, Dry Skin
Effects of Probiotics on Skin Health in Healthy Women
The effect of probiotics on skin health in healthy women with dry to very dry facial skin.
- Trial name
- NCT07887841
- Testing
- Probiotics
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Probi AB
Skin Ulcer
Safety of Cultured Allogeneic Adult Umbilical Cord or Placental Derived Mesenchymal Stem Cells for Skin Ulcer
This trial will study the safety and efficacy of intravenous infusion and intralesional injection of cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells for the treatment of Skin Ulcer
- Trial name
- NCT05158127
- Testing
- cultured allogeneic adult umbilical cord or placental derived mesenchymal stem cells
- Where
- 2 sites in United States, Greece
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Effect of Skin to Skin Care in Preterm Neonates, Skin to Skin Care
Immediate Skin-To-Skin Care For Preterm Infants After Birth
The standard procedure in our centre for preterm neonates is to enable skin-to-skin (SSC) contact within 24 hours after birth. As early SSC immediately after birth might provide numerous positive effects for mothers and their…
- Trial name
- eSCC (NCT06794164)
- Testing
- skin to skin care, Standard Care (in control arm)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Graz
AIDS-Related Kaposi Sarcoma, Skin Kaposi Sarcoma
Nirogacestat in Patients With Kaposi Sarcoma
This phase II trial studies how well nirogacestat works in treating patients with skin Kaposi sarcoma (KS). Several anti-cancer drugs work well in treating KS, but there is no treatment that cures KS.
- Trial name
- NCT07539454
- Testing
- Biospecimen Collection, Chest Radiography, Computed Tomography
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- AIDS Malignancy Consortium
Cellulitis, Skin Disease, Infectious
Naproxen Versus Placebo as Adjunct Treatment of Cellulitis
Cellulitis is a painful bacterial skin infection commonly seen in Canadian emergency departments. Cellulitis has a negative impact on patients' quality of life and productivity.
- Conditions
- Cellulitis, Skin Disease, Infectious, Infection, Skin and Soft Tissue Infections (SSTIs)
- Trial name
- NVP (NCT07665476)
- Testing
- enteric-coated naproxen, Cephalexin Tablets
- Where
- Canada
- Volunteers
- 884 people
- Sponsor
- Ottawa Hospital Research Institute
Surgical Site Infection, Skin Cancer
Cyanoacrylate Skin Adhesive After Mohs Surgery or Wide Local Excision
This study will compare surgical site infection after linear repair with or without cyanoacrylate skin adhesive following Mohs micrographic surgery or wide local excision.
- Conditions
- Surgical Site Infection, Skin Cancer, Wound Healing
- Trial name
- NCT07844681
- Testing
- Cyanoacrylate Skin Adhesive, Fast Gut Running Epidermal Suture Closure, Vicryl Rapide Running Epidermal Suture Closure
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Minnesota
Facial Wrinkles, Skin Aging
Evaluation of MD60002 Device for Facial Skin Aging
This single-center, non-controlled, single-arm clinical study is designed to evaluate the performance and safety of the Class III investigational device MD60002 (composed of highly purified polynucleotides at 3%) for aesthetic…
- Conditions
- Facial Wrinkles, Skin Aging, Skin Imperfections
- Trial name
- CIP-02-25 (NCT07881926)
- Testing
- Device: MD60002
- Where
- Italy
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Promoitalia Group Spa
Skin Cancer, Cutaneous Squamous Cell Carcinoma (CSCC)
A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision
This study is investigating the effects on immune cells of injecting the influenza vaccine (also known as "flu shot") into cutaneous squamous cell carcinoma (CSCC) tumors prior to having standard-of-care Mohs excision surgery.
- Conditions
- Skin Cancer, Cutaneous Squamous Cell Carcinoma (CSCC), Cutaneous Squamous Cell Cancer
- Trial name
- NCT06664151
- Testing
- Fluzone Trivalent
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Dana-Farber Cancer Institute
Basal Cell Carcinoma of Skin, Optical Coherence Tomography (OCT)
Real-world Evaluation of the Implementation of LC-OCT in Daily Clinical Practice
Basal cell carcinoma (BCC) is the most common skin cancer in the Netherlands, with incidence rates continuing to rise. The current diagnostic standard combines clinical evaluation and dermoscopy, while biopsy followed by…
- Conditions
- Basal Cell Carcinoma of Skin, Optical Coherence Tomography (OCT), Neoplasms, Neoplasms, Basal Cell
- Trial name
- RELI (NCT07501780)
- Where
- Netherlands
- Volunteers
- 297 people
- Sponsor
- Maastricht University Medical Center
Hidradenitis Suppurativa (HS)
A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)
This Phase 2 study will test whether the investigational medicine, SPY072, improves hidradenitis suppurativa (HS) in adults with moderate to severe disease receiving advanced standard of care treatment.
- Trial name
- NCT07766005
- Testing
- SPY072, bimekizumab
- Where
- 34 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- Spyre Therapeutics, Inc.
Skin Quality
Safety and Effectiveness of NOA HYDRATION Injectable Gel for the Improvement of Skin Quality Including Attributes Such as Skin Smoothness
Facial skin quality, including attributes such as skin smoothness, can be affected by intrinsic aging and environmental factors.
- Trial name
- NCT07880756
- Testing
- NOA HYDRATION
- Where
- 4 sites in China
- Volunteers
- 150 people
- Sponsor
- AbbVie