Clinical trials: Skin Diseases, Bacterial
Hidradenitis Suppurativa
A Randomized Trial Comparing the Efficacy and Safety of Secukinumab with Tofacitinib in the Treatment of Moderate to Severe Hidradenitis Suppurativa in Chinese Patients
The goal of this clinical trial is to compare the efficacy secukimumab versus tofacitinib in patients with moderate to severe hidradenitis suppurativa (HS)in adults.
- Trial name
- NCT06707246
- Testing
- Secukinumab 300 MG; Tofacitinib 11mg
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hidradenitis Suppurativa, Acne Inversa
A Study to Evaluate the Efficacy, Safety and Tolerability of Bermekimab in Patients With Hidradenitis Suppurativa
This study further evaluates the efficacy of bermekimab in treating moderate to severe hidradenitis suppurativa in adults. 1/3 of patients will receive weekly injections of bermekimab, 1/3 will receive alternating every other…
- Conditions
- Hidradenitis Suppurativa, Acne Inversa, Suppurative Hidradenitis
- Trial name
- NCT04019041
- Testing
- bermekimab
- Where
- 33 sites in United States
- Volunteers
- 153 people
- Sponsor
- Janssen Research & Development, LLC
Tinea Cruris
Comparative Efficacy of Topical Oxiconazole Cream (1%) Versus Topical Clotrimazole Cream (1%) in the Treatment of Tinea CrurisAbstract
This study is conducted to compare the efficacy of topical oxiconazole 1% cream versus topical clotrimazole 1% cream in patients with tinea cruris.
- Trial name
- NCT07441005
- Testing
- Topical Oxiconazole cream, Topical Clotrimazole cream
- Where
- Pakistan
- Volunteers
- 386 people, healthy volunteers welcome
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Hidradenitis Suppurativa (HS)
Real-World Study on the Burden of Hidradenitis Suppurativa
Despite the significant impact of HS on patients' quality of life (QoL) and daily functioning, there remains limited real-world evidence describing the burden of this condition in Canada.
- Trial name
- NCT07323303
- Testing
- No Intervention: Observational Cohort
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- PeriPharm
Hidradenitis Suppurativa (HS)
Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa
This study will build on data from mice and humans implicating TRPV1 nociceptors in the pathogenesis of the type-17 chronic inflammatory skin disease hidradenitis suppurativa (HS).
- Trial name
- Botox in HS (NCT07756346)
- Testing
- Botulinum Toxin A (Allergan, Inc, Irvine CA)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Worcester
Tinea Capitis
The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation
To explore carrier and infection status of T.tonsurans tinea capitis and characterize the host-pathogen interaction as it relates to the disease presentation.
- Trial name
- NCT00224926
- Testing
- Scalp Brushing
- Where
- United States
- Volunteers
- 446 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Erysipelas
Comparing Short to Standard Amoxicillin Course for Erysipelas
Erysipelas is an acute streptococcal skin infection, primarily affecting the lower limbs and easily diagnosed. In 2000, the French expert consensus conference validated oral amoxicillin at 3 to 4.5 gr per day for 10 to 20 days as…
- Trial name
- SHAREII (NCT07104552)
- Testing
- Course of amoxicillin
- Volunteers
- 656 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tuberculosis
Exogenous Reinfection of Tuberculosis in Taiwan
we hypothesize that exogenous reinfection is very important in the Taiwan endemic. Therefore, we design a series of studies to evaluate the individual contribution of exogenous reinfection and endogenous reactivation in the…
- Trial name
- NCT00173433
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Tinea
Isotretinoin In Preventing Recurrences In Chronic Recurrent Dermatophytosis
This study is a prospective, double blinded, randomized, pilot study to assess the effectiveness of oral low dose isotretinoin in combination with oral terbinafine and itraconazole in preventing recurrences in chronic recurrent…
- Trial name
- ISORD (NCT03471455)
- Testing
- Isotretinoin, Terbinafine, Itraconazole 200 mg
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Onychomycosis, Dermatophytosis
Study Evaluating the Effect of Jublia on Dermatophytomas
This study will examine how Jublia affects dermatophytomas, which are difficult to treat with other therapeutic options.
- Trial name
- NCT03098615
- Testing
- Jublia (Efinaconazole 10% Topical Solution)
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hidradenitis Suppurativa
A Randomized Controlled Trial Evaluating the Efficacy of Intralesional Triamcinolone in Hidradenitis Suppurativa.
Purpose: To evaluate the effectiveness of intralesional triamcinolone for the treatment of hidradenitis suppurativa (HS) Participants: Patients diagnosed with Hidradenitis Suppurativa that have active inflammatory HS lesions.
- Trial name
- NCT02781818
- Testing
- Triamcinolone Acetonide 10mg/mL, Triamcinolone Acetonide 40mg/mL, Normal Saline
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Rheumatic Fever
Prevalence of Rheumatic Heart Disease According to Revised Jones Criteria (2015) in Assiut Governate
Prevalence of rheumatic heart disease according to revised jones criteria (2015) in Assiut governate
- Trial name
- NCT04316897
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Onychomycosis
A Study of the Systemic Absorption of MOB015B
A Study of the Systemic Absorption of Once Daily MOB015B when Applied for 28 Days in Subjects with Moderate to Severe Onychomycosis of the Toenails.
- Trial name
- NCT03244280
- Testing
- MOB015B
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Moberg Pharma AB
Tinea Unguium, Onychomycosis
Evaluation of an Oligonucleotide Array for Rapid Identification of Dermatophytes in Clinical Specimens
The nail specimens from patients with suspect onychomycosis were analyzed. Samples were collected as part of standard patient care from the Department of Dermatology, National Cheng Kung University Hospital (NCKUH, a tertiary…
- Trial name
- NCT02270697
- Testing
- Array
- Volunteers
- 32 people
- Sponsor
- National Cheng-Kung University Hospital
Onychomycosis
Comparative Efficacy of Bifonazole Cream vs Placebo After Nail Ablation With Urea Paste
The study is focused to prove that the efficacy of a 1% Bifonazole cream is superior to a placebo cream after non-surgical nail ablation with a 40% urea paste.
- Trial name
- NCT00781820
- Testing
- Bifonazole cream 1%
- Where
- 51 sites in Czechia, Germany and 1 more
- Volunteers
- 693 people
- Sponsor
- Bayer
Psoriasis, Psoriatic Arthritis
Effectiveness of Interdisciplinary Care Compared to Usual Care in Patients With Immune-Mediated Inflammatory Diseases
The overall aim of this study is to determine the effectiveness of an interdisciplinary combined clinic intervention compared to usual care in a population of patients with two or more Immune-mediated inflammatory diseases…
- Conditions
- Psoriasis, Psoriatic Arthritis, Axial Spondyloarthritis, Hidradenitis Suppurativa
- Trial name
- NCAS-1 (NCT04200690)
- Testing
- Interdisciplinary management, Usual-care management
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Onychomycosis
Radiofrequency in Onychomycosis
Onychomycosis is the most common nail disease, representing more than 50% of all onychopathies.
- Trial name
- NCT05390190
- Testing
- Non ablative radiofrequency
- Volunteers
- 20 people
- Sponsor
- Cairo University
Hidradenitis Suppurativa (HS)
Short-term Treatment Satisfaction in Hidradenitis Suppurativa Patients Initiated on Cosentyx in Routine Clinical Practice in Saudi Arabia
This study aims to assess the treatment satisfaction of HS patients newly started on secukinumab in Saudi Arabia, in terms of patient reported convenience, perceived safety, perceived effectiveness and global treatment…
- Trial name
- ILLUMINATE-SA (NCT06785779)
- Testing
- Secukinmab
- Where
- 4 sites in Saudi Arabia
- Volunteers
- 77 people
- Sponsor
- Novartis Pharmaceuticals
Hidradenitis Suppurativa (HS), Hidradenitis Suppurativa (Acne Inversa)
Global Healthcare Study on Hidradenitis Suppurativa
The Global Healthcare Study on Hidradenitis Suppurativa (GHSHS) is an international, multicenter observational study hosted by the University of Zurich (UZH) investigating healthcare access, treatment patterns, disease severity…
- Trial name
- GHSHS (NCT07659769)
- Where
- Switzerland
- Volunteers
- 9,600 people
- Sponsor
- Julia Tatjana Maul
Complicated Skin and Soft Tissue Infection
Evaluation of Ceftaroline Fosamil vs Vancomycin Plus Aztreonam in the Treatment of Patients With Skin Infections.
The purpose of this study is to evaluate the effects of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in treatment of patients with complicated bacterial skin and soft tissue infections.
- Trial name
- NCT02202135
- Testing
- Ceftaroline fosamil, Vancomycin, Aztreonam
- Where
- 22 sites in Argentina, Brazil and 11 more
- Volunteers
- 4 people
- Sponsor
- Pfizer