Clinical trials: Skin Thickness, active
Burn, 3D Printing
Clinical Effectiveness of a Patient-tailored Orthosis Based on 3-dimensional (3D) Scanner Modeling and 3D Printing Technology for Microstomia Caused by Burns : Pilot Study
Mircostomia is not clearly defined in terms of size, but is diagnosed when it causes difficulty in eating, pronounciation, or maintaining oral hygiene.
- Conditions
- Burn, 3D Printing, Microstomia, Split Thickness Skin Graft
- Trial name
- NCT07264218
- Testing
- patient's tailored mouthpiece fitting
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Hangang Sacred Heart Hospital
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Skin Graft Scar
Surgical Outcomes of Simple Interrupted Versus Running Epidermal Sutures in Full-thickness Skin Graft Placement
The study hypothesis is that the use of running epidermal sutures in full-thickness skin graft (FTSG) placement for patients undergoing dermatologic surgery (Mohs micrographic surgery or excision) is non-inferior to the use of…
- Trial name
- NCT06233812
- Testing
- Simple interrupted suturing technique, Running suturing technique
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Skin Transplantation
Clinical and Histological Study of a Novel Dermal Substitute
The goal of this observational study is to compare a novel dermal substitute to a the current standard procedure in the treatment of full thickness skin defects.
- Trial name
- NCT06255990
- Testing
- Standard of care
- Where
- 4 sites in Switzerland
- Volunteers
- 42 people
- Sponsor
- University Children's Hospital, Zurich
Skin Transplantation, Reconstructive Surgical Procedures
Effect of Platelet-Rich Plasma on Graft Uptake and Postoperative Outcomes in Full-Thickness Skin Grafting of Face and Neck
This clinical study aims to evaluate whether applying platelet-rich plasma (PRP), a substance made from a person's own blood, can improve the success of full-thickness skin grafts used to treat facial and neck wounds.
- Trial name
- NCT07112898
- Testing
- Platelet-Rich Plasma (PRP), Standard Skin Grafting
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Lahore General Hospital
Skin Stiffness, Skin Thickness
Evaluation Skin Stiffness Gradient on Skin After LLLT
This study evaluates the effects of Low-Level Laser Therapy (LLLT) on skin elasticity by measuring a 3x3 stiffness gradient across 9 points spaced 1 cm apart.
- Conditions
- Skin Stiffness, Skin Thickness, DFU, Wound and Injuries
- Trial name
- NCT07680309
- Testing
- LLLT intervention on skin biomechanical properties in different duration and wavelength, LLLT intervention on skin biomechanical properties in different duty cycle and applied frequency
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Asia University
Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy
Extracorporeal Shock Wave Therapy in Lower Extremity Lymphedema
Lower extremity lymphedema is a chronic and progressive condition associated with significant functional impairment and reduced quality of life.
- Conditions
- Lymphedema, Lower Limb, Extracorporeal Shock Wave Therapy, Edema Leg, Sham-controlled
- Trial name
- NCT07626645
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Skin Graft Donor Site, Wound Healing
Autologous Skin Cell Suspension (RECELL®) for Accelerated Healing of Split-Thickness Skin Graft Donor Sites: A Randomized, Intra-Patient (Split-Site) Controlled Trial
This study evaluates whether applying RECELL® autologous skin cell suspension (ASCS) to one half of a split-thickness skin graft (STSG) donor site accelerates re-epithelialization and improves long-term scar quality compared with…
- Conditions
- Skin Graft Donor Site, Wound Healing, Split-Thickness Skin Graft
- Trial name
- RECELL®-STSG (NCT07888166)
- Testing
- RECELL® Autologous Cell Harvesting Device, Standard Transparent Film Dressing
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Skin Graft Wounds, Donor Site Complication
Aloe Vera vs Paraffin Tulle Dressings for Pain Management in Split Thickness Skin Graft Donor Sites
The goal of this clinical trial is to learn if Aloe Vera gel dressing helps reduce pain better than traditional paraffin-based tulle dressing at the donor site of split-thickness skin grafts in adult patients aged 18 to 60.
- Conditions
- Skin Graft Wounds, Donor Site Complication, Pain, Postoperative, Skin Transplantation
- Trial name
- AloePaTu (NCT07057557)
- Testing
- Aloe Vera Gel Dressing, Paraffin-Based Tulle Dressing
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- King Edward Medical University
Wound Closure, Wound Care
Safety Study of Microlyte DualGuard
The primary purpose of this research is to evaluate the safety and effectiveness of Microlyte® DualGuard wound dressing in the healing of partial thickness donor site wounds, also known as skin graft donor sites.
- Trial name
- SAGGA (NCT07695688)
- Testing
- Microlyte DualGuard, Allevyn Foam (Standard of Care Control)
- Where
- 3 sites in United States
- Volunteers
- 53 people
- Sponsor
- Imbed Biosciences
Prophylactic Mastectomy
Prophylactic Mastectomy: Prospective Evaluation of the Correlation Between Skin Flap Thickness, Residual Glandular Tissue and Skin Necrosis by Imaging and Clinical Examination
Breast cancer is the most common form of cancer among women. Five to ten percent of all breast cancers are due to hereditary factors, with pathogenic variants in the breast cancer genes BRCA1/2 accounting for 2-5% of all breast…
- Trial name
- NCT05162677
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Umeå University
Behçet
Role of Femoral Vein Wall Thickness and Inflammatory Markers in Patients With Behcet Disease
Evaluation of femoral vein wall thickness and inflammatory indices in patients with Behcet disease and assessment of their relation to the disease activity and related some clinical manifestations
- Trial name
- NCT06721234
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Cronic Full-thinkness Skin Wound, Acute Full-thickness Skin Wound
Efficacy of a Photosynthetic Dermal Matrix for the Treatment of Full-Thickness Skin Wounds
The goal of this clinical trial is to evaluate whether the incorporation of photosynthetic microalgae into scaffolds for dermal regeneration improves healing outcomes in adult patients with acute and cronic full-thickness skin…
- Trial name
- NCT07157657
- Testing
- Surgical implantation with standard (DRM) or photosynthetic dermal regeneration matrices (PDRM) in same patient., Autologous split-thickness skin grafting over implanted matrices
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Skin Roughness, Wrinkle
A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions
A Phase I Study of KB301, a Replication-Incompetent, Non-Integrating Vector Expressing Human Type III Collagen (COL3) for the Treatment of Superficial Skin Depressions
- Conditions
- Skin Roughness, Wrinkle, Fine Lines, Skin Thickness
- Trial name
- NCT04540900
- Testing
- KB301
- Where
- 4 sites in United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Krystal Biotech, Inc.
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Atheroscleroses, Rheumatoid Arthritis (RA
Atherosclerosis in Early Rheumatoid Arthritis Patients Using Atherogenic Index of the Plasma and Carotid Intima Media Thickness
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily affecting the peripheral joints, yet its extra-articular burden particularly on the cardiovascular (CV) system has emerged as its most consequential…
- Trial name
- NCT07772466
- Volunteers
- 70 people
- Sponsor
- Assiut University
Skin Rejuvenation, Laser
Comparative Effectiveness of Long-Pulsed 1064-nm Nd:YAG and Fractional CO₂ Laser in Skin Rejuvenation
Skin rejuvenation is an effort to improve skin condition from the signs of skin aging. Skin aging is a complex biological process influenced by intrinsic and extrinsic factors, leading to changes in the epidermis and dermis…
- Trial name
- NCT07467954
- Testing
- Fractional CO₂ laser, Long-pulsed 1064-nm Nd:YAG laser
- Where
- Indonesia
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universitas Padjadjaran
Oral Cancer, Oral Cavity Cancer
Radial Forearm Donor Site Closure
The radial forearm free flap (RFFF) is widely used in head and neck reconstruction. Its thinness, pliability, pedicle length, and vessel size are particularly suited for oropharyngeal and oral cavity reconstruction.
- Conditions
- Oral Cancer, Oral Cavity Cancer, Donor Site Complication
- Trial name
- NCT05740033
- Testing
- Split-Thickness Skin Graft for Radial Forearm Donor Site Closure, Hatchet Flap for Radial Forearm Donor Site Closure
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- University of British Columbia