Clinical trials: Sleep Restriction
Alzheimer Disease, Late Onset, Mild Cognitive Impairment
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Dementia caused by Alzheimer's disease affects approximately 5.6 million adults over age 65, with costs expected to rise from $307 billion to $1.5 trillion over the next 30 years.
- Conditions
- Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Sleep, Cognitive Change
- Trial name
- ALPS (NCT05138848)
- Testing
- Time in Bed Restriction, Sleep Schedule
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity
Sleep Timing on Energy Intake and Energy Expenditure
Studies in healthy young adults have shown that abnormal and undesirable physiological changes are a result of chronic sleep curtailment, with implications on inflammatory status, blood glucose regulation, circulating free fatty…
- Trial name
- NCT05096585
- Testing
- Delayed bedtime sleep restriction, Early wake sleep restriction
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Sleep Restriction and Energy Expenditure
Each 4-day period will follow the same protocol. Basically, for the entire study, we will prepare all of the subject's food and will require him or her to eat all of the food that we give at the times we tell them to eat.
- Trial name
- NCT01751581
- Testing
- Short Sleep, Habitual sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Acute and Partial Sleep Deprivation
Cortical Excitability and Decision Making After Total Sleep Deprivation and Sleep Restriction
The investigators examine changes in decision making, vigilance and cortical excitability in healthy male subjects undergoing total acute sleep deprivation (40 hours) on the one hand, and chronic partial sleep restriction (7…
- Trial name
- NCT02305225
- Testing
- Sleep Deprivation
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Christian Baumann
Sleep Restriction
Decision-making After Sleep Restriction
The aim of this project is to investigate whether enhancing sleep intensity locally in the prefrontal cortex (PFC) can counteract a deterioration of cognitive control and therefore the previously described increase in risk…
- Trial name
- DM-SR (NCT03692962)
- Testing
- Sleep restriction, Acoustic stimulation
- Where
- Switzerland
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Christian Baumann
Sleep
Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults
This study aims to assess whether slow wave sleep enhancement using SmartSleep technology benefits daytime cognitive performance during periods of chronic sleep restriction.
- Trial name
- NCT03911154
- Testing
- Philips SmartSleep Technology--Continuous Fixed Interval modality, Philips SmartSleep Technology--Block modality, Philips SmartSleep Technology--In-Phase Adjustable modality
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Sleep Deprivation, Hypoxia
Effect of Acute Sleep Restriction on Responses to Hypoxia
At altitude, humans are exposed to environmental hypoxia induced by the decrease in barometric pressure. On duty or in training, mountain troops, paratroopers or aircrew are regularly exposed to altitude.
- Trial name
- HypSom (NCT05563688)
- Testing
- Hypoxia exposure, Sleep deprivation, Cognitive tasks
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Sleep, Cardiovascular Disease
Impact of Sleep Restriction in Women
The overall goal of this project is to test the hypothesis that long-term, sustained sleep restriction (SR), in women, will lead to increased cardio-metabolic risk.
- Conditions
- Sleep, Cardiovascular Disease, Obesity
- Trial name
- NCT02835261
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy Volunteer
Challenging the Endocannabinoid System in Sleep Restricted Healthy Volunteers to Modulate Physiological Arousal (CANISLEEP) Study
The goal of this study is to learn about the body's response to cannabis based products in sleep deprived people who are currently experiencing anxiety but are otherwise healthy.
- Trial name
- CANISLEEP (NCT07656350)
- Testing
- THC, CBD, THC + CBD
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Diet, Healthy, Body Weight
Diet, Body Composition, Lifestyle and Cardiovascular Health of Healthy and Active Adults From Slovenia
There is objective need to evaluate the differences in dietary intake (DI), body composition (BC), lifestyle (LS) and cardiovascular diseases (CVD) risk factors between healthy and active vegetarinas (VEG) and non vegetarians…
- Conditions
- Diet, Healthy, Body Weight, Time Restricted Feeding, Sleep
- Trial name
- SloLifestyle (NCT04379622)
- Testing
- Dietary intake, body composition, lifestyle, and CVD risk factors
- Where
- Slovenia
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Barbara Jakše s.p.
Energy Restriction, Sleep Deprivation
Brain Energy and Cognition
This proposed laboratory study will extend previous findings on relationships between cognitive function and nutritional status to conditions that more closely resemble military operations where aerobic exercise, inadequate…
- Trial name
- NCT01603550
- Testing
- Sleep Deprivation, Energy Restriction
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Sleep, Blood Pressure
Impact of Sleep Restriction on Blood Pressure Reactivity
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
- Trial name
- NCT07489417
- Testing
- Sleep Restriction
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sleep, Pregnancy
Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth
Every day in Ghana, 47 babies are stillborn (SB) and 232 babies are born with low birth-weight (LBW) - many of whom will die in infancy or suffer lifelong consequences.
- Conditions
- Sleep, Pregnancy, Stillbirth, Infant, Low Birth Weight
- Trial name
- NCT02379728
- Testing
- PrenaBelt, Body Position Sensor
- Where
- Ghana
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Allan Kember
Sleep Restriction
The Effects of Individualised Short-term Sleep Restriction on Tactical Performance
The goal was to evaluate the influence that chronic sleep restriction may have on football players tactical performance during small-sided games.
- Trial name
- NCT06912256
- Testing
- Sleep restriction
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- José Afonso Coelho Neves
Obesity
The Impact of Sleep Restriction on Gastric Emptying, Appetite and Energy Intake
This study aims to examine if partial sleep deprivation results in alterations blood markers and subjective markers of homeostatic, and hedonic appetite, as well as provide initial data as to the impact of sleep restriction on…
- Trial name
- NCT05953285
- Testing
- Sleep restriction
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Hypertension
Sleep Restriction and Parental History of Hypertension
The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal…
- Trial name
- NCT06482814
- Testing
- Partial sleep deprivation (sleep restriction), Normal sleep
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sleep Apnea, Pregnancy
Pregnancy, Sleep Disordered Breathing and Peripartum Complications
Sleep disordered breathing (SDB) during pregnancy is a modifiable risk factor for poor maternal and fetal outcomes. The investigators propose a prospective observational study to assess the utility of continuous positive airway…
- Trial name
- NCT02651649
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Sleep Deprivation, Nutritional Intervention
Ketone Conferred Resiliency Against Sleep Restriction With Nutritional Intervention.
Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks.
- Trial name
- NCT06075914
- Testing
- Ketogenic Intervention, Mediterranean Intervention, Ketone Ester
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Sleep Deprivation, Sleep Restriction
Comparison Across Multiple Types of Sleep Deprivation
This study is designed to assess neurobehavioral performance, as well as genetic and other physiological changes associated with variations in timing and quantity of sleep.
- Trial name
- NCT04211506
- Testing
- Controlled sleep
- Where
- 2 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Civil Aerospace Medical Institute
Sleep Restriction, Impaired Glucose Metabolism
The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction
The purpose of the study is to examine the effects of sleep and modafinil on how the body processes glucose.
- Trial name
- NCT00895570
- Testing
- modafinil
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital