Clinical trials: Smoking, Non-Tobacco Products
Periodontitis, Dual- Light Photodynamic Therapy
Use of Dual-light Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
The goal of this controlled clinical trial is to investigate the impact of regular home use of Lumoral device as an adjunct treatment compared to non-surgical periodontitis treatment (NSPT) alone on biofilm removal and host…
- Conditions
- Periodontitis, Dual- Light Photodynamic Therapy, Smoking, Cigarette, Non-surgical Periodontal Therapy
- Trial name
- NCT05962801
- Testing
- Lumoral device, Lumorinse
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Smoking, Smoking, Cigarette
Tabata Exercise on Nitric Oxide Synthases and Maresin
Smoking causes chronic inflammation and endothelial dysfunction through alterations in nitric oxide synthase (NOS) pathways. Maresin is an anti-inflammatory pro-resolving lipid mediator that plays important roles in the…
- Trial name
- NCT07412639
- Testing
- Tabata Exercise Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Saliva, Cortisol
Comparison of Saliva Biomarkers in Two Different Geographical Regions of Turkey
Periodontitis is a multifactorial, chronic inflammatory disease caused by many factors such as pathogenic microorganisms, host response, environmental and systemic factors.
- Conditions
- Saliva, Cortisol, Smoking, Tobacco, Periodontal Bone Loss
- Trial name
- NCT06809439
- Testing
- Non-Surgical Intervention, Saliva Collection (Baseline), Probing
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Smoking Cessation
Informing Tobacco Treatment Guidelines for African American Non-Daily Smokers
The researchers are testing if counseling alone or counseling plus over-the-counter nicotine replacement therapies (NRT), like the patch,gum, or lozenge, helps African American non-daily smokers quit smoking.
- Trial name
- NCT02244918
- Testing
- Nicotine Replacement Therapy, Smoking Cessation Counseling
- Where
- 2 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Smoking, Stress
Physiological Responses in Tobacco Chippers
This study will analyze a series of biological and behavioral markers in different populations of smokers. The study groups will differ in their cigarette consumption and level of nicotine dependence.
- Trial name
- NCT01237834
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Smoking, Cigarette
Perceptions of Cigarette Smoking in Young Adults
This study focuses on menthol (n = 125) and non-menthol (n = 125) smoking young adults (YAs; defined here as ages 18 to 26).
- Trial name
- PRISM (NCT03953508)
- Testing
- Cigarette flavor type
- Where
- United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Tobacco Cessation
Intervention Study to Increase Smoking Cessation Rates Among Public Housing Residents
The purpose of this study is to determine whether public housing residents trained in Tobacco Cessation and Motivational Interviewing Techniques to become Tobacco Treatment Advocates(TTA) will be effective in increasing the quit…
- Trial name
- NCT01651611
- Testing
- Motivational interviewing, Smoking cessation counseling, Navigation to smoking cessation resources
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Boston University
THC, Cannabis
THC Crossover Study
This is a randomized, crossover study enrolling experienced dual cannabis-tobacco smokers (N=18) to describe the differences in THC and toxicant exposure, examining pharmacokinetic, subjective, and cardiovascular effects from…
- Conditions
- THC, Cannabis, Cannabis Smoking, Cannabis Use, Unspecified
- Trial name
- TRDRP (NCT04429568)
- Testing
- Smoked Cannabis, Vaped Cannabis, Tobacco Cigarette
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Sexual Behavior, Alcohol Drinking
Adolescent Safer Sex Social Network Intervention
Social networks are thought to hold the potential for shaping behavior on the grounds that social and situational factors more strongly influence behavior than do personality variables.
- Conditions
- Sexual Behavior, Alcohol Drinking, Marijuana Smoking
- Trial name
- NCT00107562
- Testing
- Adolescent Safer Sex Social Network Intervention
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Tobacco Use Cessation
VergeRx for Smokers Not Ready to Quit
This study uses a factorial optimization experiment to identify which treatment components help adults who smoke and are not ready to quit in the next 30 days (smokers not ready to quit, or SNRTQ) achieve smoking cessation.
- Trial name
- NCT07693660
- Testing
- VergeRx, SmokefreeTXT, NRT Lozenge (Combination)
- Where
- United States
- Volunteers
- 592 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Tobacco Use, Smoking
CSD200902: Assessment of Indoor Air Quality for a Heated Tobacco Product With Four Non-Combusted Cigarette Variants in an Environmental Testing Chamber
This is a single-center, open-label, parallel-cohort study to measure and compare the levels of selected secondhand smoke (SHS) constituents of a heated tobacco product (HTP) against combustible cigarettes (CC) after ad libitum…
- Conditions
- Tobacco Use, Smoking, Tobacco Smoking
- Trial name
- NCT05363254
- Testing
- Marlboro Gold Box, Newport Box, Non-combusted cigarette variant 42001401
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RAI Services Company
HRT, Non-HRT
Tobacco Cessation in Postmenopausal Women
This study investigated whether being on transdermal hormone replacement therapy (HRT) influenced smoking cessation variables in postmenopausal women undergoing short-term abstinence from cigarettes.
- Conditions
- HRT, Non-HRT, Continued Smoking, Smoking Abstinence
- Trial name
- NCT01210586
- Testing
- Part 2
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence, Cigarettes
Negotiating a Quit Date or Not in Online Interventions
The primary purpose of the current study is to test the effect of providing users of automated web-based smoking cessation interventions with the option of negotiating and re-negotiating the quit date.
- Trial name
- NCT03194919
- Testing
- Endre: a digital smoking cessation counsellor
- Where
- 2 sites in Czechia, Norway
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Alcohol Drinking, Smoking
An Effectiveness Trial of Project ALERT
The purpose of this study is to replicate a longitudinal evaluation of Project ALERT, a substance abuse prevention program that targets middle school students.
- Conditions
- Alcohol Drinking, Smoking, Marijuana Smoking
- Trial name
- NCT00650585
- Testing
- Project ALERT
- Where
- United States
- Volunteers
- 8,338 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Marijuana Smoking
Effect of Quetiapine on Marijuana Withdrawal and Relapse
The objective of this study is to investigate the interaction between marijuana and quetiapine, with the goal of using this information to improve marijuana treatment outcome.
- Trial name
- NCT00743366
- Testing
- Marijuana, Quetiapine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Immunity, Smoking, Cigarette
Impact of Solarplast® on Immunity in Active Smokers and Non-smokers
The purpose of this study is to determine the impact of Solarplast treatment on measures of oxidative stress, immune function, skin appearance, and associated measures in 60 men and women, consisting of both cigarette smokers and…
- Trial name
- NCT05162820
- Testing
- 100 mg Solarplast
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Smoking, Tobacco Use
Salt-Based E-cigarette
Electronic nicotine delivery systems (ENDS) vary on a wide range of characteristics, which may impact the reinforcement value of the products compared to more harmful combustible products.
- Trial name
- NCT04238832
- Testing
- Salt Base Nicotine, Free Base Nicotine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Underage Alcohol Use, Smoking, Non-Tobacco Products
Culturally Enhancing a Motivational Interviewing Intervention For Latinx Adolescents
The purpose of this study is to compare two versions of an intervention focused on teaching 10-14-year-old Latina/o adolescent's skills that will decrease the likelihood that they will use tobacco, alcohol, and other drugs.
- Trial name
- NCT03947177
- Testing
- GMIT, GMIT+
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Cigarette Smoking, Smoking Behaviors
Switch or Quit R01
This study evaluates whether non-cigarette tobacco products (e-cigarettes) can help smokers quit smoking as compared to traditional quit methods (nicotine replacement therapy or varenicline/Chantix).
- Trial name
- NCT06373679
- Testing
- Switching to E-Cigarette, Switching using Medication
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
THC, Cannabis
Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration
This is a crossover, randomized, double-blinded clinical pharmacology study enrolling dual cannabis-tobacco smokers to better understand the combined effects of co-administering cannabis and tobacco.
- Conditions
- THC, Cannabis, Cannabis Use, Cannabis Smoking
- Trial name
- CANNIC (NCT05999383)
- Testing
- Cannabis, Nicotine, Pax Loose Leaf Vaporizer
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco