Clinical trials: Soft Tissue Healing
Alveolar Bone Loss, Tooth Loss / Rehabilitation
Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem Membranes
After tooth extraction, the surrounding bone and soft tissue may undergo dimensional reduction. Socket preservation involves placement of a bone graft into the extraction socket and coverage with a membrane to support healing…
- Conditions
- Alveolar Bone Loss, Tooth Loss / Rehabilitation, Alveolar Bone Grafting, Socket Preservation
- Trial name
- NCT07856693
- Testing
- NOVAMag Membrane, permamem Membrane, Alveolar Socket Preservation With an Allogeneic Bone Graft
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Nevus, Seborrheic Keratosis (SK)
Impact of Skin Type on Wonud Healing and Scarring Following Facial Skin Surgery
The goal of this observational study is to learn how an individual's skin type influences the wound healing process and scar formation in Chinese patients undergoing facial dermatologic surgery.
- Conditions
- Nevus, Seborrheic Keratosis (SK), Cyst, Lipoma
- Trial name
- NCT07384299
- Where
- China
- Volunteers
- 173 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Missing Tooth
The Effect of Platform-Matching Versus Platform-Switching Dental Implants on Peri-implant Hard and Soft Tissue Healing
To compare platform-switched implants to platform-matched implants for replacement of a single missing tooth and their effect on: 1) Interproximal alveolar crest level in relation to implant platform. 2) Buccal implant recession.
- Trial name
- NCT02536716
- Testing
- Platform-matched dental implant, Platform-switched dental implant
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Dental Implant, Surgical Dental Prostheses
Low Intensity Pulsed Ultrasound Versus Low Level Laser Therapy Post Dental Implant
The purpose of the study is to investigate the significance difference between low intensity pulsed ultrasound (LIPUS) versus low-level laser therapy (LLLT) on osseointegration, soft tissue healing, pain pressure threshold and…
- Conditions
- Dental Implant, Surgical Dental Prostheses, Dental Implantation
- Trial name
- NCT05938868
- Testing
- Low intensity pulsed ultrasound (LIPUS), low level diode laser therapy, Standard Care
- Where
- Egypt
- Volunteers
- 63 people
- Sponsor
- Ahram Canadian University
Third Molars Extraction, Low Level Laser Therapy
Effects of Low-level Laser Therapy on Soft and Hard Tissue Healing After Impacted Mandibular Third Molar Extraction
Impacted lower third molar extraction is one of the most commonly performed dental procedures in daily practice. However, this is considered a relatively invasive procedure.
- Conditions
- Third Molars Extraction, Low Level Laser Therapy, Bone Healing
- Trial name
- NCT07190950
- Testing
- Low Level Laser Therapy
- Where
- Vietnam
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Abnormally Healing Wounds, Scars
Safety of Adipose-Derived Stem Cell Stromal Vascular Fraction
A single-arm, open-labeled, single-center, descriptive and exploratory safety trial using ADSC-SVF-002. ADSC-SVF-002 is an autologous adipose derived stem cell (ADSC)-containing stromal vascular fraction (SVF) obtained from…
- Conditions
- Abnormally Healing Wounds, Scars, Soft Tissue Defects
- Trial name
- NCT02590042
- Testing
- ADSC-SVF-002
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- AdiSave Inc.
Punch Biopsy Wounds, Healing Times
Healing of Punch Graft Wounds. Comparative Study Between MariGen and Oasis: a Non-inferiority Study
The objective is to determine, if healing of punch biopsy wounds treated with the fish skin derived MariGen Wound dressing is non-inferior to healing with wounds treated with pig intestines derived Oasis Sheet wound dressing.
- Trial name
- NCT01917591
- Testing
- Punch biopsies treated with MariGen Wound ECM dressing, Punch biopsies treated with Oasis ECM dressing
- Where
- Iceland
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Kerecis Ltd.
Dental Implant, Platelet Rich Fibrin
The Effect of Platelet Rich Fibrin Layers on Peri-implant Tissue Phenotype
The present investigation seeks to determine how varying quantities of Platelet-Rich Fibrin (PRF) membranes influence the repair of both gingival and osseous tissues adjacent to dental implants.
- Conditions
- Dental Implant, Platelet Rich Fibrin, Keratinized Mucosa, Crestal Bone Loss
- Trial name
- NCT07033351
- Testing
- Dental implant placement without PRF, Single-layer PRF membrane application, Triple-layer PRF membrane application
- Where
- Iraq
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
Zygomatic Implants, Atrophic Maxilla
Buccal Fat Pad vs. Palatal Rotation Scarf Grafts for Soft Tissue Management Around Zygomatic Implants
Over the past 20 years, the demand for oral rehabilitation among edentulous patients has steadily increased. Traditionally, individuals with edentulous maxillae were treated using removable complete dentures.
- Conditions
- Zygomatic Implants, Atrophic Maxilla, Soft Tissue Defect, Soft Tissue Healing
- Trial name
- RCT BFP ZAGA (NCT06968780)
- Testing
- Buccal Fat Pad, Palatal Rotation Scarf Graft
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Cairo University
Soft Tissue Defects, Soft Tissue Wounds
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Demonstrate faster tissue coverage of exposed structures using OFM in combination with negative pressure wound therapy (NPWT), versus NPWT alone
- Conditions
- Soft Tissue Defects, Soft Tissue Wounds, Traumatic Soft Tissue Defect
- Trial name
- COVER (NCT07385313)
- Testing
- Myriad™ applied in conjunction with NPWT, NPWT Alone
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Aroa Biosurgery Limited
Bone Loss, Inflammation
Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss
In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?
- Trial name
- NCT01961635
- Testing
- dental implants, Zirconia abutments, Titanium Abutments
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Wound Healing After Tooth Extraction
Comparing Cross-Linked and Non-Cross-Linked Hyaluronic Acid for Early Healing After Tooth Extraction
This study compares early healing after a non-surgical tooth extraction in adults. Participants are assigned by chance to one of three groups: cross-linked hyaluronic acid placed in the extraction site using a gelatin sponge…
- Trial name
- NCT07898163
- Testing
- Cross-linked sodium hyaluronate 1%, Non-cross-linked low-molecular-weight hyaluronic acid, Gelatin sponge
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Soft Tissue Healing
The Effect of Laser Photocoagulation on the Soft Tissue Healing During Socket Preservation
The main aim of this study was to evaluate clinically the effect of laser photocoagulation in comparison to the non-resorbable dense polytetrafluroethylene (dPTFE) membrane on the soft tissue healing during socket preservation…
- Trial name
- NCT04353999
- Testing
- Socket sealing by diode laser photocoagulation, socket sealing with dense polytetrafluroethylene membrane
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Hams Hamed Abdelrahman
Dental Implant Placement
Buccal Soft Tissue Contour Changes After Immediate Implant Placement with or Without Connective Tissue Graft
Statement of the problem: Using customized contoured healing abutments at the time of immediate implant placement is a treatment modality to improve esthetics by maintain the soft tissue contour.
- Trial name
- NCT04309006
- Testing
- CTG and customized healing abutment, CTG and conventional healing abutment
- Where
- 2 sites in Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Misr International University
Immediate Implant, Esthetic Zone
Effect of Tooth Angulation, Alveolar and Basal Bone Anatomical Characteristics on Soft and Hard Tissue Alterations Around Immediate Implants With Customized Healing Abutment
The goal of this clinical trial is to investigate the effect of different anatomical variations in terms of root angulation, alveolar bone and basal bone morphology on soft and hard tissue alterations in patients with…
- Conditions
- Immediate Implant, Esthetic Zone, Customized Healing Abutment, Tissue Collapse
- Trial name
- NCT06040788
- Testing
- immediate implant placement with customized healing abutment
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Recession
Expression of Angiogenic Biomarkers During Healing of Intra-Oral Soft Tissue Engineered Grafts
The purpose of this observational research study is to understand more about wound healing of gum tissue. This study was the biomarker study of a small cohort of study participants derived from NCT01547962 (completed).
- Trial name
- NCT01134081
- Testing
- CelTx™, Free Gingival Graft
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Periodontal Pocket, Peri-implantitis
Treatment of Periodontal and Peri-Implant Pockets With a Novel Collagen Hydrogel, H42 Medical Device
A retrospective, observational, non-profit study designed to evaluate the use of the H42 medical device in patients with periodontitis or peri-implantitis.
- Trial name
- H42 (NCT07700628)
- Where
- 3 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Studio Odontoiatrico Dott. G. Tarquini
Wound Surgical, Wound Heal
Early Healing of Oral Soft Tissues: a Clinical and Biomolecular Analysis. Part I
The purpose of the present study is to observe and compare -through a biomolecular analysis- the differences in the gene expression and cellular behavior in the early wound healing process -24 hours after injury- between the…
- Conditions
- Wound Surgical, Wound Heal, Oral Soft Tissue Conditions
- Trial name
- NCT04202822
- Testing
- Oral soft tissues biopsies
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of Roma La Sapienza
Soft Tissue Healing
Treatment of ATFL Tears With PRP
PRP will enhance ATFL tears healing by time and quality.
- Trial name
- NCT00725907
- Testing
- PGRF
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Peri-implant Soft Tissue Deficiency, Partial Edentulism
Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant Placement
Peri-implant soft tissue thickness is an important determinant of the long-term stability and success of dental implants. Patients with a thin peri-implant soft tissue phenotype are at increased risk of soft tissue recession…
- Conditions
- Peri-implant Soft Tissue Deficiency, Partial Edentulism, Tooth Loss
- Trial name
- NCT07714265
- Testing
- subepithelial connective tissue graft, Submerged Tenting Abutment, Sub-crestal Implant Placement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Misr International University