Clinical trials: Soft Tissue Injuries
Soft Tissue Injuries
Study to Determine if Shock Wave Therapy Applied to Traumatic Wounds of the Extremity Improves Healing Time
The purpose of this study is to determine if adding shock wave therapy to standard-of-care wound treatment for traumatic extremity wounds helps them heal faster.
- Trial name
- CWI (NCT00486733)
- Testing
- DermaGold
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Digital Technology, Prosthesis User
3D Evaluation of the Lip Support in a Full-arch Implant-supported Rehabilitations
The goal of this observational study is to evaluate the impact of a full arch implant-supported prostheses in the lip support. In a complex rehabilitation cases, the process between the diagnosis and the delivery of a prostheses…
- Conditions
- Digital Technology, Prosthesis User, Lip, Oral Soft Tissue Conditions
- Trial name
- NCT06052501
- Testing
- Removable of the full arch implant-supported prostheses
- Where
- Portugal
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Soft Tissue Defect of Digit, Nerve Injury
A Comparison of the Littler Flap With the Bipedicled Nerve Flap
A retrospective study is conducted with 59 patients who has a combination of soft tissue and digital nerve defects following trauma treated using the Littler flap or bipedicle nerve flap.Patients are divided into two groups.
- Trial name
- NCT03701685
- Testing
- nerve flap
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Impacted Mandibular Third Molar, Postoperative Wound Healing
Soft Tissue Healing and Bacterial Load With Triclosan-Coated Sutures After Impacted Mandibular Third Molar Surgery
The goal of this clinical trial is to learn if triclosan-coated absorbable stitches (polyglactin 910 sutures coated with triclosan, an antibacterial agent) help soft tissue heal better and have fewer bacteria stuck to the…
- Trial name
- NCT07386366
- Testing
- Triclosan-coated Polyglactin 910 suture, Non-coated polyglactin 910 suture
- Where
- Vietnam
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Trauma, Orthopedic Surgery Complications
The Infected Bone Nonunion and Soft Tissue Defect of Long Bone Treated Simultaneously With Ilizarov Technique
In this retrospective study, the investigators evaluated the clinical and functional results of infected nonunion of the long bone with soft-tissue defects treated simultaneously with Ilizarov technique combining open dressing…
- Trial name
- NCT00846261
- Testing
- Use it to treatment bone nonunion (Ilzarov)
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Breast Cancer, Surgery
Evaluation of ADM Soft Tissue Reinforcement
The use of acellular dermal matrix (ADM) has facilitated implant-based breast reconstruction, both in single-stage direct-to-implant (DTI) and staged tissue expander placement.
- Conditions
- Breast Cancer, Surgery, Surgical Item, Retained
- Trial name
- NCT03494244
- Testing
- Direct-to-implant breast reconstruction, Acellular dermal matrix
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Impacted Third Molar Tooth, Surgical Wound Healing
Antibacterial Effect and Soft Tissue Healing of Chlorhexidine-Coated Polyglactin 910 Sutures After Impacted Lower Third Molar Surgery
This study evaluates whether coating Polyglactin 910 sutures with chlorhexidine diacetate (CHX-DA) improves outcomes after the surgical removal of impacted mandibular (lower) third molars (wisdom teeth).
- Trial name
- NCT07794280
- Testing
- Chlorhexidine Diacetate-Coated Polyglactin 910 Suture, Uncoated Polyglactin 910 Suture
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Tooth Extraction Status Nos, Tooth Fracture
The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh
The study will be conducted on 30 patients with split mouth design patients will be divided into curcumin and PRF groups patients will have bilateral tooth extraction one side will receive curcumin/PRF and the other side will be…
- Trial name
- NCT05816707
- Testing
- PRF, Curcuma Longa gel, extraction socket
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rania Farouk Mohamed Abdulmaguid
Wound Healing
Effects of CGF and Collagen Fleece on Palatal Donor Site Healing: A Randomized Clinical Trial
This study investigated whether applying Concentrated Growth Factor (CGF) or Collagen Fleece (CF) to the palatal donor site after autogenous soft tissue graft harvesting could improve wound healing and reduce postoperative…
- Trial name
- PAL-HEAL (NCT07367165)
- Testing
- Concentrated Growth Factor (CGF), Collagen Fleece (CF), Collagen Sponge (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Inonu University
Gingival Recession, Periodontal Attachment Loss
Flap Thickness Upon Root Coverage With the Use of Acellular Dermal Matrix
OrACell has been tested as a barrier in bone regenerative procedures showing promising results in new bone formation after socket preservation, but no data is available on root coverage procedures.
- Conditions
- Gingival Recession, Periodontal Attachment Loss, Periodontal Diseases, Soft Tissue Injuries
- Trial name
- NCT04802473
- Testing
- Mucogingival surgery
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Diabetes, Wound Infection
Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis
This study will determine the tissue penetration of the novel tetracycline antibiotic, omadacycline (Nuzyra, Paratek Pharmaceuticals, Inc.), into the extracellular, interstitial fluid of soft tissue in diabetic patients with…
- Conditions
- Diabetes, Wound Infection, Healthy Volunteers
- Trial name
- NCT04144374
- Testing
- Omadacycline, Microdialysis Catheter Insertion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Wound Healing, Palatal Wound
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel.
- Conditions
- Wound Healing, Palatal Wound, Donor Site Complication, Inflammatory Cytokines
- Trial name
- NCT07330154
- Testing
- Application of NBF gel after soft tissue graft surgery
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Hamstring Injury, Strain Counter Strain
"THE EFFECTS OF LOW LEVEL LASER THERAPY VERSUS STRAIN/COUNTER STRAIN TECHNIQUE IN ACUTE SOFT TISSUE INJURIES"
Muscle strain injuries are common in sports but are often misdiagnosed and maltreated. Their significance is often underestimated because most athletes can continue their daily activities soon after the injury.
- Trial name
- NCT03816826
- Testing
- physical therapy
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isra University
Chronic Pain, Soft Tissue Injuries
Radiofrequency Hyperthermia Safety Study
This study will include 20 healthy subjects with intact skin on their lower legs that meet inclusion criteria. Participants will serve as their own control, by heating one leg and not the other.
- Conditions
- Chronic Pain, Soft Tissue Injuries, Wound Heal, Blood Flow
- Trial name
- NCT05399771
- Testing
- Laser Doppler, Radiofrequency Heating System, Thermal Imaging
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Pressure Ulcer, Soft Tissue Necrosis Lower Limb
Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers
Researchers at LSUHSC-S hope to learn the effects of the combination of a medication and a device which by themselves are effective for the treatment of wounds.
- Trial name
- NCT01208220
- Testing
- Negative Pressure Wound Therapy, Collagenase Ointment
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Soft Tissue Wound Healing
Effect of Hyaluronic Acid on Oral Mucosal Wound Healing - Focus on Pain and Re-epithelisation
Establishment of a sufficiently wide and thick keratinized gingival/mucosal tissue cuff around teeth/implants is considered of importance for long-term stability.
- Trial name
- NCT05099718
- Testing
- palatal soft tissue harvesting, Hyaluronic acid
- Where
- Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Malmö University
Finger Injuries
Reconstructive of Multiple-digit Soft-tissue Defects Using Regional Dorsal Digital Flaps
Reconstruction of soft-tissue defects in multiple digits poses a significant challenge. This article reports simultaneous reconstruction of multiple small-to-moderate soft-tissue defects using regional dorsal digital island flaps…
- Trial name
- NCT03717220
- Testing
- flap transferring
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Tangshan
Microcirculation, Wound Healing
Hyperbaric Oxygen Therapy in Calcaneal Intraarticular Fractures: Can it Decrease the Soft-tissue Complication Rate?
This study aims to test the hypothesis that postoperative daily hyperbaric oxygen therapy (HBOT) decreases soft-tissue complication rate during the operative handling of intra-articular calcaneal fractures. Minor motivations: 1.
- Trial name
- HOCIF (NCT01264146)
- Testing
- HBOT
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Peri-Implantitis, Occlusal Trauma
All on Six Versus Parallel Implant Distribution for Maxillary Denture Opposing Mandibular All on Four
Thirty maxillary edentulous patients with previous mandibular All-on-4 screw retained prosthesis and their age ranged from 55 to 65 years were selected from the outpatient clinic, of prosthodontics Department, Faculty of…
- Conditions
- Peri-Implantitis, Occlusal Trauma, Implant Complication
- Trial name
- ASPISRMSDOMF (NCT05960500)
- Testing
- implant
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University