Clinical trials: Soreness, Muscle
Muscle Weakness, Myalgia
Coenzyme Q10 in Older Athletes Treated With Statin Medications
The purpose of this study is to evaluate the effect of coenzyme Q10 administration in improving mitochondrial function as measured by anaerobic threshold in older athletes on a stable dose of statin medication.
- Conditions
- Muscle Weakness, Myalgia, Side Effects of Statins
- Trial name
- NCT01026311
- Testing
- Coenzyme q 10
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Richard Deichmann, MD
Exercise-induced Muscle Soreness
Effects of Traumeel®S Tablets on Exercise Induced Muscle Damage and Muscle Soreness
To investigate and compare the effects of Traumeel®S tablets versus placebo on exercise induced muscle damage and muscle soreness for 72 hours after strenuous eccentric exercise test on downhill treadmill.
- Trial name
- NCT01912469
- Testing
- Traumeel
- Where
- Germany
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. med. Frank Christoph Mooren
Physical Performance Parameters, Exercise Recovery
Effects of Beef-Forward Ready-to-Eat Meals on Recovery Following Simulated Fire Suppression Activities
This clinical trial aims to determine whether consuming beef-based protein before and after physically demanding simulated firefighting activities improves recovery, physical performance, and cognitive performance in healthy…
- Conditions
- Physical Performance Parameters, Exercise Recovery, Cognition, Muscle Damage
- Trial name
- FIRE-BEEF (NCT07822048)
- Testing
- Beef-Based Protein Ready-to-Eat Meals, Plant-Based Protein Ready-to-Eat Meals
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sam Houston State University
Headache, Cervical Pain
Effectiveness of Yoga@Work to Reduce Head and Muscle Pain in Office Workers
The primary objective of this study is to evaluate the effectiveness of a workplace yoga intervention in reducing the frequency of pain involving the head and neck area.
- Conditions
- Headache, Cervical Pain, Musculoskeletal Pain
- Trial name
- NCT04313491
- Testing
- Yoga
- Where
- United Kingdom
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Aarogyam UK
Recovery Strategies After Simulated 400-meter Sprint in University Athletes
Effect of Combined Active Recovery and Foam Rolling Enhance Lactate Clearance and Reduce Muscle Soreness Following a Simulated Running Competition
This study investigates the effects of combining Active Recovery (AR) and Foam Rolling (FR) on blood lactate, heart rate, and muscle soreness in competitive 400-meter sprint athletes.
- Trial name
- ARFR (NCT07439523)
- Testing
- Active Recovery + Foam Rolling, Active Recovery Only
- Where
- Indonesia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Delayed Onset Muscle Soreness, DOMS
COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS)
The study is designed as a proof of concept, single-center, randomized, double-blind, placebo controlled study to assess the safety and efficacy of Comboprofen (Ibuprofen + Magnesium + Vitamin C) compared to placebo, Ibuprofen…
- Trial name
- NCT03223519
- Testing
- Comboprofen, Ibuprofen, Magnesium
- Where
- Spain
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Spherium Biomed
Muscle Pain, Injection Site Pain
Effects of TPR and Z Techniques on Pain and Drug Leakage in Intramuscular Injections
This randomized, triple-blind clinical trial compares the effectiveness of Z-track and TPR (traction-pressure-release) techniques in reducing pain and medication leakage during ventrogluteal intramuscular injections.
- Trial name
- TPR_Z_PainLeak (NCT07004166)
- Testing
- Z-track method, TPR method
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Fatigue, Physical Exercise
Associations Between Low Frequency Fatigue, Jump Height and Perceptual Measures of Muscle Soreness, Fatigue and Recovery
Over the recent years, the increased competitive demands in elite competitive athletes has sparked a heightened interest in monitoring fatigue. Given the nature of the soccer game, athletes may experience low-frequency fatigue.
- Trial name
- NCT06458166
- Testing
- Assessment of low frequency fatigue using low frequency eletrical stimulation
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Maia
Inflammation, Muscle Recovery
The Effect of Aspalathus Linearis on Muscle Soreness and Post-exercise Recovery in Young, Physically Inactive Women
Exercise has been found to exert beneficial effect on overall health. However, it also induces muscle damage at the same time. This then leads to muscle pain, temporary inflammation and reduced muscle function.
- Conditions
- Inflammation, Muscle Recovery, Muscle Soreness
- Trial name
- NCT06561750
- Testing
- Rooibos tea, Control
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Type 2 Diabetes, Healthy Individuals
The Effects of Orally Ingesting Branched Chained Amino Acids on Delayed Onset Muscle Soreness in Diabetic Patients
The purpose of this study is to determine the effectiveness of the 3 Branched Chained Amino Acids (isoleucine, leucine, and valine) on treating Delayed Onset Muscle Soreness, a type of muscle pain which usually develops after…
- Trial name
- NCT01211717
- Testing
- Branched Chained Amino Acids
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Muscle Injury, Muscle Soreness
Effects of Wobenzym® Plus in Healthy, Sportive People After Eccentric Exercise
The aim of the current study is to investigate the therapeutic effect and especially the mode of action of Wobenzym® plus, an anti-inflammatory drug containing proteolytic enzymes, on exercise induced muscle damage (eiMD) and…
- Conditions
- Muscle Injury, Muscle Soreness, Exercise Induced Muscle Damage
- Trial name
- 2012-005003-40 (NCT01845558)
- Testing
- Wobenzym® plus
- Where
- Germany
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Mucos Pharma GmbH & Co. KG
Muscle Soreness
Vegan Whey Protein for Muscle Anabolism and Post-exercise Recovery
This study will be a randomised, double-blind trial where participants will be randomly assigned to consume either a i) vegan whey protein; ii) a whey protein; or iii) a non-protein carbohydrate control supplement for 3 days…
- Trial name
- NCT07119749
- Testing
- Stable isotope tracer consumption, DXA scan, Controlled diet
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Cardiopulmonary Testing in ME/CFS to Improve Diagnostic Accuracy
Circumstantial evidence suggests that patients diagnosed with myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) perform worse on day 2 in a 2-day consecutive cardiopulmonary exercise test (CPET).
- Trial name
- NCT02970240
- Testing
- Cardiopulmonary testing
- Where
- Norway
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Muscle Soreness
Effects of Riboflavin in Mitigating Muscle Soreness in Ultra-marathon Athletes
The aim of this project is to investigate the effects of riboflavin, also known as vitamin B2, on preventing delayed onset muscle soreness (DOMS) in ultramarathon athletes through a randomized placebo-controlled study.
- Trial name
- NCT05907850
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Steven Moore
Pain, Acute
Controlled Study to Assess the Efficacy and Safety of S-Ibuprofen Topical Gel 5% (AP0302) in the Treatment of DOMS
Phase 2 study designed to evaluated analgesic efficacy and safety of S-Ibuprofen Topical Gel 5%
- Trial name
- NCT03852459
- Testing
- S-Ibuprofen, Vehicle
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Aponia Laboratories, Inc.
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Muscles
Rates of Recovery From Strenuous Exercise in Physically Active Older Adults
The purpose of this study to determine if older adults who are healthy and physically active (i.e., Masters athletes) demonstrate slower rates of recovery from unaccustomed strenuous exercise of downhill running than younger…
- Trial name
- NCT02899650
- Testing
- exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Muscle Fatigue, Trapezius Muscle Strain
Short Interventions to Prevent Trapezius Muscle Fatigue in Computer Work
This study is expected to demonstrate that during experimental days of seated computer work sustained and focalized low-level muscle activity contributes to the development of long-lasting fatigue effects (and thus possible…
- Trial name
- NCT03863340
- Testing
- interruptions of work tasks
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Menstrual Cycle Phase
Menstrual Cycle and Exercise-induced Muscle Damage
The aim of the study is to investigate the effect of the different menstrual cycle phases on the recovery from exercise-induced muscle injury in eumenorrheic women.
- Trial name
- MC-EIMD (NCT07322874)
- Testing
- Exercise during follicular phase, Exercise during luteal phase
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chariklia K. Deli
Delayed Onset Muscle Soreness, DOMS
Study of SST-0225 Topical Ibuprofen Cream in the Treatment of Delayed Onset Muscle Soreness (DOMS)
This is a Phase 3, prospective, randomized, dual-center, double-blind, placebo-controlled, parallel-group study designed to determine the efficacy and safety of SST-0225 (5.4 grams, applied up to 6 times in 24 hours, over a…
- Trial name
- DOMS (NCT02597634)
- Testing
- SST-0225
- Where
- 3 sites in United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Strategic Science & Technologies, LLC