Clinical trials: Spinal
Anesthesia; Reaction, Anesthesia
Efficacy and Safety of Prilocaine 2% and Lidocaine 5% Hyperbaric Against Spinal Anesthesia in Post Cystoscopy Procedure
Regional anesthesia is defined as the temporary removal of nerve conduction and pain in certain areas of the body with local anesthetic drugs without causing loss of consciousness.
- Trial name
- NCT05834647
- Testing
- Prilocaine 2%, Hyperbaric Lidocaine 5%
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Amyotrophic Lateral Sclerosis, Alzheimer's Disease
Advances in Telephone-based Cognitive Screening Procedures
1. Background Cognitive screening procedures via performance-based tests represent an essential, albeit preliminary, element within the diagnostic and interventional process as addressed to patients with chronic neurological…
- Conditions
- Amyotrophic Lateral Sclerosis, Alzheimer's Disease, Lewy Body Dementia, Frontotemporal Degeneration
- Trial name
- TBCS (NCT06337578)
- Testing
- Telephone-based neuropsychological assessment - ALS, Telephone-based neuropsychological assessment - AD, LBD, FTD and CVD, Telephone-based and in-person cognitive screening - NIs
- Where
- Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Stroke, Healthy
Operant Conditioning for Neuromodulation
Emerging evidence demonstrates that animals and people can exert control over the level of excitability in spinal and corticospinal neural circuits that contribute to movement.
- Trial name
- NCT03461159
- Testing
- Operant conditioning of H-reflexes, Operant conditioning of motor evoked potentials
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stacey Dejong
Atelectasis, Cesarean Section
Atelectasis by Lung Ultrasonography in Cesarean Sections
In this study aimed to demonstrate that atelectasis developing in the perioperative period of patients undergoing elective cesarean surgery with spinal or general anesthesia methods using lung ultrasound.
- Trial name
- NCT04591327
- Testing
- The Effect of General Anesthesia and Spinal Anesthesia on Postoperative Atelectasis by Lung Ultrasonography in Cesarean Sections
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Derince Training and Research Hospital
Amyotrophic Lateral Sclerosis
Optic Coherence Tomography in Patients With Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis (ALS) is an adult-onset, devastating, neurodegenerative disease characterized by the loss of cortical, brain stem, and spinal motor neurons.
- Trial name
- NCT03377868
- Testing
- Optic coherence tomography, Pulmonary function test
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Symptomatic Lumbar Spinal Stenosis, Lumbar Spinal Stenosis
Muscle Function and Pelvic Stability While Walking in Patients With Symptomatic Lumbar Spinal Stenosis
This study is to quantify changes in muscle activity and pelvic stability during prolonged walking in patients with symptomatic lumbar spinal stenosis (sLSS) and healthy control subjects and to determine their association with…
- Trial name
- WALK-LSS (NCT03951935)
- Testing
- Oswestry Disability Index (ODI) questionnaire, self-paced walking test (SPWT)
- Where
- Switzerland
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Hypotension
Up-Down Determination of the ED90 of Metaraminol to Treat Hypotension During Cesarean Section
The purpose of this study is to find the best dose of metaraminol to be used in patients during elective cesarean sections.
- Trial name
- NCT01108874
- Testing
- Metaraminol
- Where
- Brazil
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Degenerative Disc Disease, Spondylolisthesis, Lumbar Region
Clinical Effectiveness of Pre-operative Methadone in Single Level Lateral Transpsoas Interbody Fusions
Spinal operations including lumbar fusions for degenerative disorders are becoming more prevalent as the population ages. Inadequate or excessive postoperative analgesia can result in medical comorbidities and prolonged hospital…
- Trial name
- NCT04112550
- Testing
- Methadone Hydrochloride, Oxycodone-Acetaminophen
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Poliomyelitis
Assessment of Poliovirus Type 2 Immunogenicity of One and Two Dose Schedule With IPV and fIPV When Administered at 9-13 Months of Age in Bangladesh
Following a recommendation on October 2017 meeting of the Strategic Advisory Group of Experts (SAGE) on Immunization; low- risk bOPV-using countries may adopt 2 dose fIPV schedule prior to global OPV cessation as it provides…
- Trial name
- NCT03890497
- Testing
- IPV
- Where
- 2 sites in Bangladesh
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Intrathecal Dexmedetomidine
This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).
This study aims to determine whether lower doses (4 µg) of intrathecal dexmedetomidine can provide comparable analgesic benefits while minimizing adverse hemodynamic effects in patients encountered in our setup( Shifa…
- Trial name
- NCT07807020
- Testing
- Intrathecal Dexmedetomidine
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shifa International Hospital
Spinal Cord Injury
Neuroplasticity After Spinal Cord Injury
The long-term goal is to acquire scientific knowledge that can be used to develop mechanistic-driven intervention strategies aiming at restoring upper and lower-limb motor function in individuals with cervical or thoracic spinal…
- Trial name
- NCT02446210
- Testing
- Magstim 200, Digitimer electrical stimulator
- Where
- United States
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Patient Self-managed BCI-FES
This study aims to assess the feasibility of therapist-caregiver-patient training to use BCI and FES technology with a view to the inexpensive equipment eventually being used for home use by tetraplegic patients as a continuing…
- Trial name
- NCT03257982
- Testing
- BCI-FES hand therapy
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
ALS, ALS (Amyotrophic Lateral Sclerosis)
Systems Biology of Amyotrophic Lateral Sclerosis (ALS)
The goal of this observational study is to identify molecular features in multiple clinical samples and/or the patient environment that are associated with ALS.
- Trial name
- NCT07007390
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Viome
SMA II, Cerebral Palsy
Paracetamol Study in Patients With Low Muscle Mass
To investigate the safety and toxicity related to paracetamol treatment in children and adults with respectively SMA and CP.
- Trial name
- NCT03648658
- Testing
- Paracetamol 120Mg/5mL Oral Suspension
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mette Cathrine Oerngreen
Back Pain, Intervertebral Disc Degeneration
The Role of Disc Nutrition in the Etiology and Clinical Treatment of Disc Degeneration
The purpose of this research study is to examine the effects of physical therapy on the spinal discs. Back pain is the number one cause of disability in the US, and the spine is the most common location of chronic pain in…
- Trial name
- NCT04134910
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Spinal Cord Injury
Sympathetic-Somatomotor Coupling in Human Spinal Cord Injury
Significance: The long term objective of this study is to improve physical therapy and fitness programs in people with spinal cord injury.
- Trial name
- NCT02115685
- Testing
- Treadmill Training
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Lumbar Spine Disease
3D Model - Classification of Thoracic and Lumbar Spinal Fractures.
The goal of this clinical trial is to evaluate and compare the effectiveness of a 3D interactive model versus traditional teaching methods in enhancing the teaching of thoracic and lumbar spine fractures classification (AO Spine)…
- Trial name
- NCT06379776
- Testing
- Education through a 3D model, Education through a traditional pedagogical support
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Université Paris-Sud
Spinal Anesthesia Induced Hypotension, Geriatric
Internal Jugular Vein Ultrasound for Predicting Hypotension in Geriatric Patients Undergoing Spinal Anesthesia
Spinal anesthesia-induced hypotension is a common and clinically significant complication in geriatric patients. Accurate preoperative assessment of intravascular volume status may help identify patients at risk.
- Conditions
- Spinal Anesthesia Induced Hypotension, Geriatric, Internal Jugular Vein, Ultrasonography
- Trial name
- IJV-SPINAL (NCT07411313)
- Testing
- Not applicable- observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Spinal Cord Injury
Spinal Cord Stimulation for Functional Recovery in Humans With Tetraplegia
In support of the long-term goal of developing new strategies to increase limb function after SCI, the objectives of this proposal are to: 1) Examine the behavioral and physiological effects of TESS on upper-limb muscles after…
- Trial name
- NCT05157282
- Testing
- TESS, Training, Motor Task
- Where
- 2 sites in United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
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