Clinical trials: Spinal
Poliomyelitis
Study to Evaluate the Safety of Co-administration of GSK Biologicals' Poliorix and Infanrix in Healthy Children in Russia
The purpose of this study is to assess reactogenicity and safety of simultaneous administration of GSK Biologicals' inactivated poliomyelitis vaccine Poliorix and GSK Biologicals' DTPa-vaccine Infanrix vaccines in healthy…
- Trial name
- NCT01094171
- Testing
- Poliorix TM, Infanrix TM
- Where
- 2 sites in Russia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Rheumatoid Arthritis, Spondyloarthritis
Safety and Efficacy of Anti-Pandemic H1N1 Vaccination in Rheumatic Diseases
The prognosis of rheumatic diseases has improved considerably with development of therapy. However, infections are considered the most important cause of morbidity and mortality in this group of patients.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Systemic Lupus Erythematosus (SLE), Dermatomyositis (DM)
- Trial name
- NCT01151644
- Testing
- Anti-pandemic H1N1 influenza vaccine
- Where
- Brazil
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anesthesia; Sexual, Analgesia
The Effect of Peripheral Nerve Blocks on Postoperative Analgesia in Elective Cesarean Section
The goal of this prospective randomized study was to compare the efficacy of transversus abdominis plane block and transversalis fascia plane block for postoperative analgesia in patients undergoing elective cesarean section…
- Trial name
- NCT05758233
- Testing
- Patients undergoing transversalis fascia plane block, Patients undergoing transversus abdominis plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Breathing Exercise, Pranayama
Effect of Kinesio Tape and Breathing Exercises in Hyperkyphosis
The aim of this study was to evaluate the effects of breathing exercises alone and in combination with kinesiotape application on pain experience, postural alignment, sleep quality, anxiety level, and respiratory capacity in…
- Conditions
- Breathing Exercise, Pranayama, Kinesio Taping, Hyperkyphosis
- Trial name
- NCT07028307
- Testing
- Breathing Exercises, Breathing Exercises + Kinesio Taping Group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Healthy Young Adults
Remote Ischemic Conditioning and Spinal Reflex Modulation
Remote ischemic conditioning (RIC) is a clinically feasible method that protects distant organs from severe injury through brief, sub lethal periods of ischemia followed by re-perfusion.
- Trial name
- NCT06860464
- Testing
- Remote Ischemic Condtioning (RIC), Balance training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- East Carolina University
Intraoperative Hypotension
The Use of Integrated Pulmonary Index During Cesarean Section Under Spinal Anesthesia
Postspinal hypotension (PSH) is a common side effect with an incidence of 15.3 to 33% that can result in organ hypoperfusion and ischemic events.
- Trial name
- NCT05237856
- Testing
- Capnometry Monitorization
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Spinal Muscular Atrophy (SMA)
Spinal Muscular Atrophy (SMA) Biomarkers Study in the Immediate Postnatal Period of Development
Spinal muscular atrophy (SMA) is the leading genetic cause of death of infants. Strong preclinical evidence suggests that effective therapy must be delivered as early as possible to prevent progression of the disease.
- Trial name
- NCT01736553
- Where
- 15 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Diphtheria, Tetanus
Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series
The purpose of this study is to evaluate immunogenicity and safety of different doses of candidate hexavalent vaccine in comparison to co-administration of Pentavalent vaccine and Poliomyelitis Vaccine (Inactivated) in separate…
- Conditions
- Diphtheria, Tetanus, Pertussis, Hepatitis B
- Trial name
- NCT05457946
- Testing
- LBVD (Hexavalent vaccine), Pentavalent vaccine and Inactivated Polio vaccine (Sabin strains)
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- LG Chem
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Morphine Adverse Reaction
Intrathecal Dexamethasone and Atropine on Morphine Induced Post-operative Nausea and Vomiting on Caesarean Section
Pain is a major problem during the postoperative period and can be considered as a challenge for the anesthesiologist. Low dose intrathecal morphine is proven efficient as a mode to reduce postoperative pain.
- Trial name
- NCT05560542
- Testing
- Atropine and Dexamethasone
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Scoliosis
Possibilities and Limitations of a New Method for the Measurement of Spine Dynamics During Gait
The full body marker sets that are typically used in opto-electronic 3D gait analyses either disregard the spine entirely or regard it as a rigid structure.
- Trial name
- NCT01803256
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital Basel
Extremity Injury
Management of Chronic Pain in Military Patients With Injuries Sustained During Active Duty
The purpose of this study is to determine the degree to which spinal cord stimulation added to comprehensive medical management can provide increased relief of chronic pain in patients with injuries sustained while on active…
- Trial name
- War Wounded (NCT01616342)
- Testing
- Spinal cord stimulator
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sceptor Pain Foundation
Underdevelopment; Congenital Malformation, Lower Limb, Scoliosis
Measurements Of Lower Limbs And Spine Based On Biplanar Radiographs: Microdose Compared To Standard Dose Protocol
Evaluation of accuracy and reliability of 2D and 3D measurements of the spine and lower limbs in adults based on biplanar radiographs with MicroDose protocol compared to a standard dose protocol
- Trial name
- NCT02332018
- Testing
- Biplanar x-ray images
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome
Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis
Motor neuron disease (MND) or ALS is a nervous system disease. ALS leads to a loss of movement ability that eventually leads to death. At the moment, there is no known treatment for ALS.
- Conditions
- ALS (Amyotrophic Lateral Sclerosis), Postpoliomyelitis Syndrome, Spinal Muscular Atrophy
- Trial name
- MotorMarker (NCT05663008)
- Testing
- 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-EMG)
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Poliomyelitis
Fractional Inactivated Poliovirus Vaccine Booster and Rotavirus Study
This is an open-label phase IV, randomized controlled trial of inactivated poliovirus vaccine (IPV) and rotavirus vaccines. This trial will assess immunogenicity of a booster dose of fractional IPV (fIPV) in comparison with a…
- Trial name
- fIPV (NCT02847026)
- Testing
- IPV at 14 and 22 weeks of age, Rotarix, IPV at 14 and 22 weeks of age, RotaTeq, IPV at 14 and fIPV at 22 weeks, Rotarix
- Where
- Bangladesh
- Volunteers
- 1,144 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Spinal Cord Injuries, Neuropathic Pain
Identifying Body Awareness-related Brain Network Changes During Cognitive Multisensory Rehabilitation for Reduced Neuropathic Pain in People With Spinal Cord Injury
Many adults with spinal cord injury (SCI) suffer from long-term debilitating neuropathic pain. Available treatments, including opioids, are ineffective at eliminating this pain.
- Trial name
- NCT04706208
- Testing
- Cognitive Multisensory Therapy, Usual Care, Clinical Assessment
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Depression, Postpartum, Labor Pain
CSE v. Epidural for Postpartum Depression
The purpose of this pilot prospective randomized control trial is to compare the initiation of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on risk for postpartum depression symptoms.
- Trial name
- COPE (NCT03022526)
- Testing
- CSE, Epidural, Bupivacaine / fentaNYL
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Disc Degenerative Disease, Spondylolisthesis
A Clinical Study of a Spine Fusion System in Vertebral Body Fusion Surgery
The primary objective of this study is to demonstrate that the efficacy and safety of Spine fusion system manufactured in China is no inferior than imported product.
- Conditions
- Disc Degenerative Disease, Spondylolisthesis, Spinal Fracture, Spinal Deformity
- Trial name
- NCT02252185
- Testing
- Johnson&Johnson Medical Suzhou made Spine Fusion System, Imported EXPEDIUM screws and OPAL cage
- Where
- 8 sites in China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Medical (Suzhou) Ltd.
Breast Feeding, Analgesia
Breastfeeding Evaluation of Puerperal Women Who Had Cesarean Delivery in Our Hospital
İntroduction The World Health Organisation (WHO) and United Nations Children's Fund (UNICEF) recommends that infants are exclusively breastfed for a minimum of 6 months, with continued breastfeeding recommended until child age of…
- Trial name
- NCT06682871
- Testing
- Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Nausea and Vomiting
Gabapentin to Reduce Postoperative Nausea and Vomiting
The intrathecal administration of morphine is gaining popularity. It is easy to do and can reduce the pain after surgery up to 24 hours.
- Trial name
- NCT02944981
- Testing
- Gabapentin
- Where
- Thailand
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
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