Clinical trials: Spinal
Arthritis, Psoriatic, Psoriasis
Study Evaluating the Safety and Efficacy of Etanercept in Patients With Psoriatic Arthritis Treated by Dermatologists
The purpose of this study is to evaluate the safety profile and the effectiveness of etanercept under usual care settings in patients with PsA treated by dermatologists.
- Conditions
- Arthritis, Psoriatic, Psoriasis, Skin Diseases, Papulosquamous
- Trial name
- NCT00293709
- Testing
- etanercept
- Where
- Germany
- Volunteers
- 129 people
- Sponsor
- Pfizer
Cervical Spinal Stenosis, Cervical Myelopathy
CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes
The study will consist of two parts: In Study A, objectively assessed physical activity, gait, balance, range of movement of specific joints during walking and neurophysiological findings between patients with cervical spine…
- Trial name
- NCT04381663
- Testing
- conservative treatment, surgical treatment
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University Hospital, Basel, Switzerland
Poliomyelitis, Polio
Immunogenicity and Safety of Imovax Polio in Chinese Infants Compared to Local OPV
This study is intended to support the registration of IMOVAX Polio in China. The primary objective of this Pase III trial is to compare IMOVAX Polio to the current Chinese standard of care (OPV) that is administered following a…
- Trial name
- NCT00348387
- Testing
- Poliomyelitis Vaccine inactivated, Poliomyelitis Vaccine in Dragee Candy (Human Diploid Cell)
- Where
- 2 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Cesarean Section Complications
Vasopressor Prophylaxis After Spinal Anesthesia
Norepinephrine has been recently introduced as a prophylactic vasopressor during Cesarean delivery with promising results ; However, the optimum dose for efficient prophylaxis with the least side effects is not known.
- Trial name
- NCT03234816
- Testing
- Norepinephrine 0.05 mcg /Kg/min, Norepinephrine 0.1 mcg /Kg/min, Norepinephrine 0.15 mcg /Kg/min
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Cairo University
Acute Spinal Cord Injury
Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury
Patients with traumatic spinal cord injury (tSCI) often suffer from spinal cord swelling inside the thecal sac, which contains the spinal cord and surrounding fluid, leading to increased pressure on the spinal cord tissue and…
- Trial name
- NCT06654804
- Testing
- Perflutren lipid
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Washington
Spinal Cord Injuries, Physical Inactivity
An Online Rehabilitation Programme for People with SCI
The goal of this feasibility study is to explore the feasibility and effectiveness of a 12-week online rehabilitation programme in people with Spinal Cord Injury during the transition from hospital to home.
- Conditions
- Spinal Cord Injuries, Physical Inactivity, Spinal Cord Injury, Acute
- Trial name
- NCT06583538
- Testing
- Giraffe Healthcare
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Glasgow Caledonian University
Amyotrophic Lateral Sclerosis
Inspiratory Muscle Training With Powerbreath Device in Patients With ALS
Abstract: Context/background: people affected by Amyotrophic Lateral Sclerosis (ALS) see their own life totally disturbed after the diagnosis.
- Trial name
- NCT04889248
- Testing
- Inspiratory Muscle Training with Powerbreath IMT device.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Francisco de Vitoria
Multiple Sclerosis, Transcranial Direct Current Stimulation
The Effects of Two Types of t-DCS Stimulation on Robot-assisted Gait Training in Patients With Multiple Sclerosis
The primary aim of this study is to determine the transcranial direct current stimulation and transcutaneous spinal direct current stimulation in addition to robot-assisted walking training in individuals with Multiple sclerosis…
- Trial name
- NCT06121635
- Testing
- Transcutaneous Spinal Direct Current Stimulation and Transcranial Direct Current Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Istanbul Medeniyet University
Sleep Apnea, SCI/D
Effect of Hypercapnia Treatment on Respiratory Recovery After Spinal Cord Injury
It is estimated that 1,275,000 people in the United States alone live with spinal cord injury, including around 100,000 Veterans with spinal cord injury, making the V.A.
- Conditions
- Sleep Apnea, SCI/D, Hypercapnia
- Trial name
- RECOV2SCI (NCT05536076)
- Testing
- Hypercapnia treatment
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries, Urinary Diversion
Efficacy and Safety of a Continent Cutaneous Urinary Diversion in Spinal Cord Injury Patients
Continent Cutaneous Urinary Deviation (CUD), using the Mitrofanoff, Yang-Monti or Casale principle, is offered to patients with neurological diseases who are unable to perform intermittent catheterisation through the native…
- Conditions
- Spinal Cord Injuries, Urinary Diversion, Neurogenic Bladder
- Trial name
- ELESDUCCBM (NCT04936217)
- Testing
- Data collection, Interview using a validated questionnaire
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Spinal Cord Stimulation, Deep Brain Stimulation
Implantable Systems Performance Registry
The Implantable Systems Performance Registry (ISPR) was developed to evaluate the long-term reliability and performance of market-released Medtronic Neuromodulation infusion and stimulation products.
- Conditions
- Spinal Cord Stimulation, Deep Brain Stimulation, Drug Infusion (Implantable Pumps), Sacral Neuromodulation
- Trial name
- ISPR (NCT00959296)
- Testing
- Various
- Where
- 50 sites in United States, Austria and 5 more
- Volunteers
- 10,981 people
- Sponsor
- MedtronicNeuro
Spondyloarthritis (SpA)
Vunakizumab in Adults with Spondyloarthritis
This prospective, single-arm, multicenter study is aimed to explore the efficacy and safety of Vunakizumab in adults with spondyloarthritis.
- Trial name
- V SPA (NCT06770088)
- Testing
- vnacicizumab
- Volunteers
- 880 people
- Sponsor
- Sun Yat-sen University
Spinal Cord Injuries, Tetraplegia
Influence of Upper Extremity Vibration on Spasticity and Function in Persons With Tetraplegia
Vibration therapy is a possible alternative to drug-based treatments for spasticity following SCI. Research indicates that it may provide temporary relief from spasticity, but many interventions under investigation are not…
- Trial name
- NCT04020770
- Testing
- Vibrating ball
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shepherd Center, Atlanta GA
Spinal Cord Injury
STIMO: Epidural Electrical Simulation (EES) With Robot-assisted Rehabilitation in Patients With Spinal Cord Injury.
STIMO is a First-in-Man (FIM) study to confirm the safety and feasibility of a closed-loop Epidural Electrical Stimulation (EES) in combination with overground robot assisted rehabilitation training for patients with chronic…
- Trial name
- STIMO (NCT02936453)
- Testing
- Device implantation
- Where
- Switzerland
- Volunteers
- 12 people
- Sponsor
- Jocelyne Bloch
Spinal Metastasis
RELIEVE: Research on Effectiveness of Surgery and Radiotherapy on Relieving Spine Tumor Pain in Patients with Vertebral Metastases
This is a prospective, multicenter, observational study focusing on assessing and managing pain in patients with metastatic spinal tumors.
- Trial name
- RELIEVE (NCT06746103)
- Testing
- Surgery
- Volunteers
- 250 people
- Sponsor
- AO Foundation, AO Spine
Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy
Randomized Controlled Clinical Study of Biplanar Ultrasound-guided Puncture of Lumbar Interforamen
The goal of this clinical trial is to compare Xplane ultrasound with radiography for guidance of lumbar interforamen puncture in patients with lumbar disc herniation.
- Conditions
- Lumbar Disc Herniation, Percutaneous Endoscopic Lumbar Discectomy, Three-dimension Ultrasound, Learning Curves
- Trial name
- NCT06315803
- Testing
- Real-time 3D Xplane ultrasound
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Yi Mao
Lumbar Spondylitis
Thoracic Mobility Versus Hip Mobility Exercises to Core Stabilization in Lumbar Spondylitis
This study is conducted to determine the effect of thoracic mobility versus hip mobility exercises to core stabilization on pain severity (NPRS-Ar), functional disability (MODI-Ar), lumbar range of motion (BROM), spinal mobility…
- Trial name
- TME-HME (NCT07482527)
- Testing
- Group A : Core stabilization exercises (control group), Group B: Thoracic Mobility Exercises (1st experimental group only), Group C: Hip Mobility Exercises (2nd experimental group only)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Grade-II Cervical Spondylosis
Effects of Clinical Based Versus Synchronized Telerehabilitation on Pain, Exercise Adherence, and Functional Disability Among Patients With Grade-II Cervical Spondylosis.
This randomized controlled trial aims to compare the effects of clinical-based rehabilitation and synchronized telerehabilitation on pain, exercise adherence, and functional disability in patients with Grade-II cervical…
- Trial name
- NCT07679373
- Testing
- Group A: Clinical Based Rehabilitation, Group B: Synchronized Telerehabilitation
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Hypermobility Syndrome
Spinal Stabilization Exercise Effects in Hypermobility
The aim of this study is to investigate the effects of an 8-week lumbar spinal stabilization exercise program on pain, trunk muscle endurance and postural stability in women with benign joint hypermobility syndrome
- Trial name
- NCT02869373
- Testing
- spinal stabilizaton exercise
- Volunteers
- 38 people
- Sponsor
- Ataturk Training and Research Hospital
Amyotrophic Lateral Sclerosis, Stroke
Telehealth Implementation of Brain-Computer Interface
Determine if Telehealth intervention can allow/empower a caregiver (who is untrained) to effectively implement and utilize a Brain-Computer Interface for communication with a participant who is "Locked in" following progression…
- Trial name
- NCT05951556
- Testing
- Use of BCI
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
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