Clinical trials: Spinal Manipulation
Back Pain
Spinal Manipulation and Spinal Mobilization Effects in Participants With and Without Back Pain
The objective of the present study is to compare the neuromechanical responses to spinal manipulation and spinal mobilization in participants with chronic nonspecific middle back pain.
- Trial name
- NCT02660801
- Testing
- Spinal manipulation, Spinal mobilization
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Spinal Stenosis Lumbar
Chiropractic Distraction Spinal Manipulation- Lumbar Stenosis Study
To assess the effect of chiropractic distraction manipulation on postural sway and simple measures of performance in patients with the clinical diagnosis of lumbar spinal stenosis.
- Trial name
- Stenosis (NCT03863769)
- Testing
- Lumbar Spinal Stenosis
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Parker University
Pain
Pressure Pain Thresholds and Basal Electromyographic Activities Following Spinal Mechanical Manipulation
The purpose of this study is to investigate if the application of spinal mechanical manipulation on low back region resulted in changes in pressure pain thresholds (PPT) in asymptomatic subjects and the extent of the hypoalgesia…
- Trial name
- NCT01469533
- Testing
- Spinal mechanical manipulation intervention
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Musculoskeletal Manipulations
The Effect of Thoracic Spine Manipulation on Peripheral Neurodynamic Mobility
No studies have investigated the effects of a supine thoracic spine manipulation (TSM) on neurodynamic mobility, as compared to a sham intervention.
- Trial name
- NCT02842918
- Testing
- Spinal Manual Therapy, Spinal Range of Motion
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Lumbar Spine Injury, Pain
Looking Beyond the Immediate Effects of Lumbar Spinal Manipulation Using Pain Pressure Threshold in Asymptomatic Individuals
The goal of this clinical trial is to test in the effects of pain pressure threshold (PPT) looking out to 30 minutes in the lumbar spine.
- Trial name
- LumbarPPTUMary (NCT06156605)
- Testing
- Sidelying lumbar manipulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Mary
Lumbar Disc Herniation
Brain Effect Mechanism of Spinal Manipulative Therapy on LDH Analgesia Based on Multimodal MRI
The clinical symptoms of Lumbar Disc Herniation (LDH) can be effectively ameliorated through Spinal Manipulative Therapy (SMT), which is closely linked to the brain's pain-regulating mechanisms.
- Trial name
- NCT06277739
- Testing
- Spinal Manipulative Therapy
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Heart Rate
Effects of Instrument-Applied Spinal Manipulative Therapy on Postureal Control and Autonomic Balance
The purpose of this study is to determine the effects of spinal manipulative therapy on autonomic balance and to determine if there exists a relationship between autonomic state and postural control.
- Trial name
- NCT00380341
- Testing
- Instrument-applied spinal manipulative therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Subluxation of Joint of Lumbar Spine
The Effects of Spinal Manipulation on Thigh Muscle Strength
The purpose of this study was to investigate the effects of chiropractic low back adjustments on thigh muscle strength. Force production was measured during different types of muscle contractions with a device called an…
- Trial name
- NCT02407418
- Testing
- Spinal Manipulation
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Grant Sanders
Low Back Pain, Neuromuscular Subluxation of Joint
Effects of Dynamic Stabilizatıon Exercises and HVLA Manipulatıon in Low Back Paın
Our aim is to contribute to the literature by comparatively examining the effects of DNS exercises and chiropractic HVLA manipulation on pain, pain-related functional impairment (disability), physical competence level, dynamic…
- Trial name
- DNSHVLA (NCT06277700)
- Testing
- Chiropractic Manipulation (HVLA - high velocity low amplitude), Dynamic Neuromuscular Stabilization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Safety Issues
MIST3: Active Patient Safety Reporting
This study will seek to describe and understand adverse events (AE) severity ratings.
- Trial name
- MIST3 (NCT04161677)
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Parker University
Physiology of Manipulation / Mobilization in Healthy Adults
A Study of the Effects of Mid-Thoracic Spinal Manipulation and Spinal Mobilization on Heart Rate Variability
Spinal mobilization and spinal manipulation are common techniques utilized in the field of physical therapy. Despite their common utility, little is known about the physiological mechanisms underlying the changes experienced…
- Trial name
- NCT02380599
- Testing
- Spinal Manipulation, Spinal Mobilization
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount St. Mary's College, Los Angeles, CA
Chronic Pain, Manipulation
Comparison of the Effect of Spine Grade I and II Manipulation and a PNE Video on Brainwaves: Pilot Study
The purpose of this study is to determine the effect of the use of a pain neuroscience educational video instruction on brainwave activity and compare this to the effects of a grade I \& II PA spinal oscillations of the spine…
- Conditions
- Chronic Pain, Manipulation, Psychologic
- Trial name
- NCT04908670
- Testing
- Understanding Pain in less than 5 minutes, and what to do about it! https://www.youtube.com/watch?v=C_3phB93rvI, PA manipulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Florida Gulf Coast University
Low Back Pain, Spinal Manipulation
Comparison of The Effectiveness of Spinal Manipulation and Yoga in Chronic Low Back Pain
The aim of our study was to compare the effectiveness of chiropractic manipulation and yoga-based exercise techniques on pain, functionality, depression and anxiety in patients with long-term low back pain.
- Conditions
- Low Back Pain, Spinal Manipulation, Yoga
- Trial name
- CTESMYCLBP (NCT06291168)
- Testing
- Chiropractic Manipulation (HVLA - High Velocity Low Amplitude), Yoga-Based Exercise Program, Conventional Exercises
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Vertebral Artery Dissection, Cerebrovascular Accident
Changes in Cerebral Blood Flow With Spinal Manipulative Therapy vs. Voluntary Motion
The investigators are performing a study to determine whether changes in blood flow occur in the neck and back of the brain following a series of head positions and a manipulation of the upper neck.
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Cerebrovascular Stroke
- Trial name
- NCT01205490
- Testing
- head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Spinal Manipulation, Neck Pain
Chiropractic Care for Neck Pain: Comparing Diversified Technique and Drop Table Method
This study aims to compare the effects of two different chiropractic techniques, Diversified and Drop Table, on pain levels, cervical joint range of motion, and neck muscle strength in individuals with non-specific neck pain.
- Conditions
- Spinal Manipulation, Neck Pain, Non Specific Neck Pain, Chiropractic
- Trial name
- CDTDTM (NCT07034144)
- Testing
- Drop Table Technique, Cervical Spine Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Chronic Low-back Pain
Mechanisms of Chiropractic Spinal Manipulation for Chronic Low Back Pain
This is a mechanistic randomized controlled trial on the effects of chiropractic spinal manipulative therapy on patients with chronic low back pain.
- Trial name
- NCT05162924
- Testing
- Spinal Manipulation
- Where
- Spain
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Real Centro Universitario Maria Cristina
Pain Threshold
Additive Effects of Combined Spinal Manipulations on Pain Pressure Threshold
Physical therapists frequently use spinal manipulation therapy (SMT) to treat spinal pain. However, the methods by which SMT exerts its effects are not well understood.
- Trial name
- NCT02828501
- Testing
- Spinal Manipulation
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Posture
The Effects of Cervical Spine Manipulation On Postural Control
The purpose of this study is to test the effect of high velocity low amplitude (HVLA) chiropractic cervical manipulation on the patient's postural control as measured by a force plate.
- Trial name
- NCT00524654
- Testing
- HVLA chiropractic manipulation
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Lumbar Disc Herniation, Multimodal Brain Function
Brain Effect Mechanism of Lever Positioning Manipulation on LDH Analgesia Based on Multimodal MRI
In order to further investigate the key brain targets and central response mechanism characteristics of analgesia, the dominant disease of LDH was taken as the object of this study, which was divided into operation group, comfort…
- Conditions
- Lumbar Disc Herniation, Multimodal Brain Function, Analgesia Mechanism, Lever Positioning Manipulation
- Trial name
- NCT05613179
- Testing
- Group1 (lever positioning manipulation)
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Lumbar Disc Herniation, Gait Analysis
Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
Prospective Observation Study of the Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
- Conditions
- Lumbar Disc Herniation, Gait Analysis, Manual Therapy
- Trial name
- NCT03858556
- Testing
- Chuna manipulation, Herbal medicine, Bee venom pharmacopuncture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation