Clinical trials: Spine Surgeries
Spine Disease, Spinal Fractures
Evaluation of the Safety and Efficacy of Smart Orthopedic Minimally Invasive Surgical Systems for Spinal Surgery
To evaluate the safety and effectiveness of the intelligent orthopedic minimally invasive surgery system developed by Shenzhen Xinjunte Intelligent Medical Equipment Co., Ltd. in spinal surgery.
- Trial name
- NCT04956588
- Testing
- surgical robot, controlled approach
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Peking University Third Hospital
Robotic Surgical Procedures, Spinal Surgery
Clinical Trial for the Application of Robotic System in Spinal Surgery
This randomized controlled study was designed to evaluate the accuracy, safety and clinical outcomes of the robot assisted spinal surgery.
- Conditions
- Robotic Surgical Procedures, Spinal Surgery, Safety
- Trial name
- NCT03512379
- Testing
- TIANJI Robot, Fluoroscopy, Navigation
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Jishuitan Hospital
Cervical Spine Disease, Psychological Impairment
The Confounding Burden of Psychological Impairments in Cervical Spine Surgery
This is a single-center prospective randomized investigation of patients undergoing surgical arthrodesis for single or multi-level cervical disease, resulting in cervical radiculopathy.
- Trial name
- NCT03183713
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Low Back Pain
Assessing the Quality of Telephone Follow-Up After Spine Surgery
The aim of this study is to investigate whether the quality of physiotherapy follow-up after spinal surgery can be maintained when conducted by telephone rather than in-person.
- Trial name
- NCT07173413
- Testing
- Telephone post-surgery physiotherapy follow-up, In person post-operative physiotherapy follow-up
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Opioid Use, Spine Fusion
Does Preoperative Pain Medication Management Influence Surgical Outcomes in Spinal Fusion
In light of the current opioid epidemic, there is an urgent need to address chronic opioid use prior to surgery before it is exacerbated by postoperative surgical pain.
- Trial name
- NCT04095624
- Testing
- Spinal Fusion Preoperative Opioid Taper, Non-taper Control
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Stanford University
Spinal Fusion
Artoss Prospective Spine Registry Outcomes
This prospective registry was designed as an observational study to ascertain how commercially available NanoBone Bone Graft is being used by surgeons performing spinal fusion as well as determining relevant patient outcomes.
- Trial name
- ASTRO (NCT04439032)
- Testing
- NanoBone Bone Graft Substitute
- Where
- 6 sites in United States
- Volunteers
- 330 people
- Sponsor
- Artoss Inc.
Spine Disease
GDFT Based on PPV Compared With Standard Fluid Therapy in Patients Undergoing Complex Spine Surgery: RCT
The investigators will do the Goal directed fluid therapy by protocolized fluid management in the experimental group, using PPV to guide the fluid administration, compare with standard fluid management in patients undergoing…
- Trial name
- NCT03164811
- Testing
- goal directed fluid therapy, Controlled
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Mahidol University
Spinal Curvature
Prospective Cohort Study of Outcome After Minimally Invasive Posterior Cervical Spine Surgery
In case of cervical foraminal stenosis without central stenosis, there are several options; anterior discectomy and fusion (ACDF), tubular retractor assisted micro-foraminotomy (MTPF) and posterior percutaneous cervical…
- Trial name
- PECD (NCT02486107)
- Testing
- surgical procedure
- Where
- 3 sites in South Korea
- Volunteers
- 156 people
- Sponsor
- Seoul National University Hospital
Spine Surgery
Effect of TIVA With Magnesium Sulfate on IONM in Patients Undergoing Spine Surgery
Anesthesia for neurosurgery requires balancing deep and effective anesthesia as well as postoperative analgesia versus the risks of delayed recovery and postoperative respiratory depression.
- Trial name
- NCT04716439
- Testing
- Spine Surgery
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- King Khalid University Hospital
Cervical Spine Fusion
Navigation Image Accuracy Test in Cervical Spine Surgery Using Anatase Spine Surgery Navigation System
The "Anatase" Spine Surgery Navigation System used in this study has obtained market approval in Taiwan(MOHW-MD-No.006663) and the United States (510(k) Numbers: K180523 and K220348).
- Trial name
- NCT06117267
- Testing
- Anatase Spine Surgery Navigation System
- Volunteers
- 8 people
- Sponsor
- China Medical University Hospital
Bleeding, Anemia
Relationship Between Temperature and Intraoperative Bleeding in Patients Undergoing Multilevel Spinal Surgery
The primary objective of this multicentric observational study is to define the role of intraoperative temperature decrease (defined as reduction of at least 1 ° C during surgery) as haemorrhagic risk factor, evaluated as…
- Trial name
- NCT03909711
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Nausea, Vomiting
Efficacy of Dexamethasone Added to Ramosetron for Preventing Postoperative Nausea and Vomiting in Highly Susceptible Patients Following Spine Surgery
The purpose of this study is to study the efficacy of dexamethasone added to ramosetron for preventing postoperative nausea and vomiting in highly susceptible patients following spine surgery.
- Trial name
- NCT01013012
- Testing
- ramosetron with saline, ramosetron with dexamethasone
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative, Pain
Effect of Erector Spinae (ESP) Block on Opioid Reduction and Enhanced Recovery After Posterior Cervical Spine Surgery
Patients undergoing spine surgery frequently experience significant pain after surgery. This can limit patient activity and hinder rehabilitation.
- Trial name
- NCT04646707
- Testing
- Erector Spinae (ESP) Block with Lidocaine/Bupivacaine
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- University Health Network, Toronto
Lumbar Spinal Stenosis, Thoracic Spinal Stenosis
Effectiveness Study of the Drug Tranexamic Acid to Reduce Post-surgery Blood Loss in Spinal Surgery
Hypothesis: Topical application of Tranexamic acid into the surgical wound during spine surgery will decrease the overall blood loss post-operatively. This reduction in blood loss will reduce the need for transfusion.
- Trial name
- NCT02063035
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Massachusetts General Hospital
Spondylolisthesis, Degenerative Lumbar Disc Disease
Spine Research With Roentgen Stereophotogrammetric Analysis
The purpose of this study is to gather information on the effectiveness of a new spine implant for patients who require spinal fusion surgery.
- Conditions
- Spondylolisthesis, Degenerative Lumbar Disc Disease, Spinal Stenosis
- Trial name
- SpineRSA (NCT00493558)
- Testing
- Trabecular Metal Intervertebral Cage with RSA beads
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Nova Scotia Health Authority
Anxiety, Pain
Text Message Study
The objectives of this double-blind, randomized, controlled study are to evaluate the efficacy of maintaining contact with low-back pain patients through text messaging and emailing, to decrease anxiety levels, pain, number of…
- Conditions
- Anxiety, Pain, Surgical Site Infection
- Trial name
- NCT01789697
- Testing
- cellular device/computers
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Lumbar Spine Surgery, Quality of Life
Assessment of the Effects of Maela Connected Follow-up on Well-being and Pain After Lumbar Spine Surgery
Digital technologies could reduce the length of hospital stay and improve post-operative recuperation after discharge by offering a remote follow-up.
- Conditions
- Lumbar Spine Surgery, Quality of Life, Pain
- Trial name
- HOSPITEL (NCT05680259)
- Testing
- Maela connected follow-up, traditional follow-up
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Airway Edema
Visual Examination of Airway Via Flexible Fiberoptic Scope After Cervical Spine Surgery
Airway swelling and edema after cervical spine surgery(CSS) especially in prone position is the direct cause that prohibits patient from extubation.
- Trial name
- NCT06230315
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- State University of New York - Upstate Medical University
Degenerative Disc Disease
Study of an Expandable Interbody Device for the Lumbar Spine
The primary objective of this study is to evaluate the safety and efficacy of CALIBER expandable spacer for the treatment of degenerative disc disease.
- Trial name
- CALIBER (NCT02075554)
- Testing
- CALIBER
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Globus Medical Inc
Radiculopathy, Myelopathy
RHINE™ Cervical Disc Clinical Study: A Prospective Observational Study for Patients Requiring 1-2 Level C-spine Surgery
A Prospective, open label, multi-center observational study of patients requiring surgical treatment at one or two (contiguous) cervical spine levels.
- Conditions
- Radiculopathy, Myelopathy, Spondylosis, Herniated Nucleus Pulposus
- Trial name
- NCT02403453
- Testing
- Rhine Cervical Disc
- Volunteers
- 68 people
- Sponsor
- K2M, Inc.