Clinical trials: Sprain of Ankle
Ankle Sprain
Cast Immobilization Versus Functional Therapy for Acute, Severe Lateral Ankle Sprains
Acute, severe lateral ankle sprains are estimated to comprise between 3-5% of emergency department visits and are the most common musculoskeletal injury in the physically active population.
- Trial name
- NCT01446341
- Testing
- Below knee plaster casting, Functional rehabilitation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ankle Inversion Sprain, Instability, Joint
The Effect of Balance Training on Neuromuscular Control in Subjects With CAI
The goal of this study is evaluate the effect of uni-axial versus multidirectional balance training on muscle reaction time in subjects with chronic ankle instability.
- Conditions
- Ankle Inversion Sprain, Instability, Joint, Treatment, Neuromuscular Control
- Trial name
- NCT03439930
- Testing
- Balance training
- Volunteers
- 60 people
- Sponsor
- University Ghent
Chronic Ankle Instability, Ankle Sprain
Impact of Chronic Ankle Instability on Jumping and Agility in Athletes
This study investigated how chronic ankle instability (CAI) affects functional performance in athletes compared with healthy controls.
- Conditions
- Chronic Ankle Instability, Ankle Sprain, Functional Performance Deficit, Athletic Performance
- Trial name
- NCT07171398
- Testing
- Functional Performance Testing Battery
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Ankle Sprain
FS-67 in the Treatment of Pediatric Patients With Ankle Sprain
The objective of this study is assess the efficacy and safety of single and multiple applications of the FS-67 patch in the treatment of ankle sprain in pediatric population (ages 13-17).
- Trial name
- NCT01037816
- Testing
- FS-67 Patch
- Where
- 23 sites in United States
- Volunteers
- 252 people
- Sponsor
- Hisamitsu Pharmaceutical Co., Inc.
Chronic Ankle Instability
On the ICC's Path: a Prevalence Study
The number of trailers is growing all the time, and TRu seems to be a risky activity for the ankle joint. Ankle sprains can lead to significant health consequences, as in the case of chronic ankle instability.
- Trial name
- SSICC (NCT06269471)
- Where
- France
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Ankle Injuries
Investigation of Corticosteroid Versus Placebo Injection in Patients With Syndesmotic Ligament Injury or High Ankle Sprain
This study evaluates the use of corticosteroids acutely as an adjuvant treatment of the high ankle sprain. Subjects will receive either a corticosteroid or a local anesthetic injection.
- Trial name
- NCT02892500
- Testing
- bupivacaine hydrochloride and betamethasone sodium phosphate, bupivacaine hydrochloride
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Sanford Health
Ankle Sprains, Chronic Pain
Effects of Closed Chain Exercise Versus Neuromuscular Training on Chronic Ankle Sprain in Football Players
A current study will be conducted to determine the effects of closed-chain exercise versus neuromuscular training on pain, range of motion, and functional performance in football players with a chronic ankle sprain.
- Trial name
- NCT05981560
- Testing
- Group A - Closed Chain Exercise, Group B - Neuromuscular Training Exercise
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Lateral Ankle Sprain, Ankle Injuries
PRICE vs PEACE and LOVE in Adolescent Lateral Ankle Sprain Rehabilitation
This study compared two early management strategies for adolescents with first-time lateral ankle sprain: the traditional PRICE protocol (Protection, Rest, Ice, Compression, Elevation) combined with non-steroidal…
- Conditions
- Lateral Ankle Sprain, Ankle Injuries, Sprain of Lateral Ligament, Rupture of Ligaments at Ankle and Foot Level
- Trial name
- NCT07287020
- Testing
- PRICE + NSAIDs protocol, PEACE and LOVE protocol
- Where
- Lithuania
- Volunteers
- 76 people
- Sponsor
- Lithuanian University of Health Sciences
Ankle Sprain
Changes in Brain-Muscle Coupling After Microneedle-Knife Therapy for Ankle Sprain
This study evaluated changes in brain-muscle coordination in patients with ankle sprain after one session of microneedle-knife therapy.
- Trial name
- NCT07839260
- Testing
- Microneedle-Knife Therapy
- Where
- China
- Volunteers
- 11 people
- Sponsor
- Affiliated Dongyang Hospital of Wenzhou Medical University
Chronic Ankle Instability, Lateral Ankle Sprain
Fu's Subcutaneous Needling for Postacute Lateral Ankle Sprain and Prevention of Chronic Ankle Instability
Introduction: Fu's Subcutaneous Needling (FSN) is a new type of acupuncture treatment method based on the subcutaneous tissue sweeping technique, and it has been proven to have a good therapeutic effect on ankle sprain.
- Trial name
- NCT07161427
- Testing
- Fu's Subcutaneous Needling therapy, Ankle joint aids combined with exercise therapy
- Volunteers
- 62 people
- Sponsor
- Guangzhou University of Chinese Medicine
Ankle Sprains
Combined Effects of Talocrural MWM and Therapeutic US on Pain, Balance and Disability in Athletes With Ankle Sprain
Combined Effects of Talocrural MWM and Therapeutic US on Pain, Balance and Disability in Athletes With Ankle Sprain. Study consist of two groups.
- Trial name
- NCT06866808
- Testing
- talocrural MWM and Therapeutic US, Conventional physiotherapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Ankle Sprains, Musculoskeletal Injury
Effectiveness of Transcranial Direct Current Stimulation (tDCS).
Reducing pain and recovery of strength and function are major challenges in physical therapy. Transcranial direct current stimulation (tDCS) is a novel intervention that has gained popularity in the rehabilitation of athletic…
- Trial name
- NCT04902274
- Testing
- Transcranial Direct Current Stimulation, Physical Therapy
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Keller Army Community Hospital
Sprain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Transdel Pharmaceuticals is investigating a topical cream formulation consisting of 10% ketoprofen for the local treatment of pain associated with mild to moderate acute soft tissue injury in this confirmatory Phase 3 trial.
- Trial name
- NCT01223053
- Testing
- Ketoprofen 10% cream
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Ankle Injuries
5% Topical Ibuprofen (IBU) for Ankle Sprain
This study is being conducted to evaluate the effects of IBU 5% Topical Gel versus topical placebo for the relief of pain associated with a first or second degree ankle sprain.
- Trial name
- NCT01945034
- Testing
- Topical IBU twice daily, Topical IBU three times daily
- Where
- 19 sites in United States
- Volunteers
- 304 people
- Sponsor
- Pfizer
Ankle Sprains, Ankle Injuries and Disorders
Agreement Between Clinician and Instrumented Laxity Assessment
Ankle injuries are the most common acute injury to the active population. It is important to ensure best practices and techniques used in clinics for evaluation are validated and consistent.
- Trial name
- NCT03309098
- Testing
- Ligmaster Arthrometer Assessment
- Sponsor
- University of Nebraska
Ankle Sprains, Motor Coordination or Function; Developmental Disorder
Project Hypnos: The Impact of a Brief Hypnosis Intervention on Single-limb Dynamic Balance in People With Chronic Ankle Instability
This study will determine the relationship of one's self-reported awareness of their body and their ankle motor control for people with chronic ankle instability.
- Trial name
- NCT06390072
- Testing
- Self-Hypnosis, Ankle Education
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ohio University
Ankle Sprain
Effects of Talocrural Joint Mobilizations in the Treatment of Subacute Lateral Ankle Sprains
The goal is to determine if standard therapy including joint mobilizations of the ankle performed 3 times per week for 2 weeks will increase self-reported function and decrease pain in patients with mild lateral ankle sprains.
- Trial name
- NCT01117909
- Testing
- Mobilization therapy in addition to standard therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Virginia
Ankle Sprains
Efficacy of Kinesio Taping and Splinting in Ankle Sprain
Question:Does kinesiotaping(KT) reduce oedema, pain, disability and increase range of joint motion on patients with acute ankle ligament injuries? Design:Two-group, randomised, controlled trial with blinded assessors.
- Trial name
- NCT03634280
- Testing
- Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Istanbul Bilgi University
Ankle Sprains
Effect of Mobilization in Conjunction With Exercise in Participants With a History of Chronic Ankle Instability
Our purpose is to examine the combined effects of thrust mobilization of the ankle joints in conjunction with a six-week rehabilitation program on functional performance in subjects reporting chronic ankle instability (CAI).
- Trial name
- NCT03428620
- Testing
- High Velocity Low Amplitude mobilization, Exercise protocol
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Patients With Grade II Ankle Sprain
Effect of Allopurinol Administration on the Prevention of Muscle Mass Loss in Subject Immobilized.
Generating critical levels of power is a prerequisite for performing simple daily activities, such as rising from a chair or climbing stairs.
- Trial name
- NCT01987570
- Testing
- Allopurinol
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Instituto de Investigacion Sanitaria La Fe