Clinical trials: Standard of Care
Headache, Intranasal Ketamine
"THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department"
This is a randomized, single-blind, placebo controlled trial to evaluate the efficacy of sub-dissociative dose ketamine versus standard care therapy for acute headache management of in patients presenting to the emergency…
- Trial name
- THINK (NCT03081416)
- Testing
- Ketamine, Normal saline, Metoclopramide
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Migraine Headache
Peri-neural Electrical Dry Needling Migraine Treatment Study
This study seeks to determine the effectiveness of a specific treatment protocol using dry needling with perineural electrical stimulation in comparison to standard treatment in physical therapy for patients with migraine…
- Trial name
- NCT04252391
- Testing
- Perineural electrical dry needling, Standard Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wheaton Franciscan Healthcare
Depression, Anxiety
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
A randomized controlled trial comparing pharmacogenomic guided versus standard pharmacist care to optimize antidepressant drug therapy.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03591224
- Testing
- Pharmacogenomic Testing, Pharmacist Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- John Papastergiou Pharmacy Ltd
Rhytides
Comparison of AmnioFix Laser and Standard of Care Treatment
This is a comparison trial with novel application of AmnioFix and a control arm. Patients electively being treated with facial lasers will be assigned to receive AmnioFix in addition to the normal standard of care placed on half…
- Trial name
- NCT02659124
- Testing
- AmnioFix plus Standard of Care, Standard of Care
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Diabetic Foot Ulcers
Omeza Products in Combination With Standard of Care for the Treatment of Diabetic Foot Ulcers
This study is to evaluate the efficacy of OCM™ used in combination with off-loading devices for the treatment of diabetic foot ulcers.
- Trial name
- NCT05417425
- Testing
- Omeza collagen matrix, Omeza lidocaine lavage, Omeza skin protectant
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Omeza, LLC
Contraceptive Usage, Telemedicine
Telemedicine Contraceptive Counselling (TECC) Versus Standard Care
Overall purpose of the PILOT and RCT: This research project aims to increase access and uptake of contraception after abortion through the systematic development and testing of a new telemedicine service for contraceptive…
- Trial name
- TECC (NCT06682065)
- Testing
- Telemedicine for contraceptive counseling (TECC), Standard Care
- Where
- 2 sites in South Africa
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Intraoperative Bleeding, Post-operative Bleeding
Study to Compare the Addition of Floseal to Our Standard of Care to Control Post Operative Bleeding in TKR
The purpose of this study is to compare Floseal to our standard of care (SOC) to decrease intraoperative and immediate post-operative bleeding.
- Trial name
- NCT01891461
- Testing
- Floseal
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Polycystic Ovarian Syndrome, Obesity
Post-Prandial Liver Glucose Metabolism in PCOS
The Investigators will measure if hepatic metabolism is upregulated in obese girls with PCOS and hepatic steatosis (HS), compared to PCOS without HS and obese controls without HS.
- Conditions
- Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
- Trial name
- PLUM (NCT03041129)
- Testing
- oral glucose tolerance test, MRI of liver
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Skin Reaction to Mechanical, Thermal and Radiation Stimuli, Skin Sensitisation
Study Comparing iNPWT Dressing and Devices Affect on Bioburden Levels and Skin Condition After Seven Days
Incisional dressings aim to prevent contamination of an incisional wound and protect against skin irritation. Surgeons use incisional negative pressure wound therapy (iNPWT) to manage incisional wounds.
- Trial name
- HHiNPWT7DC (NCT05559697)
- Testing
- Sponsor incisional negative pressure wound therapy device and dressing, Standard of Care incisional negative pressure wound therapy system
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- DeRoyal Industries, Inc.
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Modified Atkins Diet, Autism Spectrum Disorder
Efficacy of MAD as add-on Therapy in Comparison With Standard of Care in Children With ASD
In general ketogenic diet is a recognized as an efficient non pharmacological treatment for children with refractory epilepsy. However, in the last decade, it has been tried for many neurological disorders in children including…
- Conditions
- Modified Atkins Diet, Autism Spectrum Disorder, Standard of Care
- Trial name
- NCT06315465
- Testing
- Modified Atkin's Diet with standard of care, Standard of Care
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Rotator Cuff Tears, Shoulder Surgery
Regeneten Patch vs Standard Care in Partial Thickness Rotator Cuff Repair
Shoulder pain is a common complaint with the most common reason being tendinopathy and/or tearing of the rotator cuff. While many rotator cuff tears are often considered normal, age-related degenerative disorders, with either…
- Trial name
- NCT04673344
- Testing
- Regeneten Collagen Patch
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Postpartum Period
Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care
Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are…
- Trial name
- NCT06963047
- Testing
- Ultrasound, Standard care
- Where
- Israel
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Medication Reconciliation Between Patients' Self Report and Electronic Medical Record List
Standard Medication Reconciliation Protocol in the Primary Care Office-based Setting
The purpose of this study is to determine if two basic medical office visit interventions improve the agreement of medication lists between electronic medical record and patient self, home-based report.
- Trial name
- NCT01577602
- Testing
- Printed medication list, Open ended question, Combined intervention
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Hepatitis C, Hepatitis C, Chronic
Enhancing Hepatitis C Testing and Treatment Among People Who Inject Drugs Attending Needle and Syringe Programs
This project aims to evaluate two strategies of Hepatitis C virus (HCV) testing compared to standard of care among people who inject drugs at needle and syringe program (NSP) services in Australia, to see if it can improve the…
- Trial name
- TEMPO (NCT04014179)
- Testing
- Xpert HCV Viral Load Fingerstick, Aptima HCV Quant DX Assay
- Where
- 17 sites in Australia
- Volunteers
- 1,801 people, healthy volunteers welcome
- Sponsor
- Kirby Institute
Hip Prosthetic Joint Infection
Efficacy and Safety Study of Antibiotic Treatment to Treat Hip Prosthetic Joint Infection
The purpose of this study is to evaluate the efficacy of oral linezolid-rifampin combination therapy (over 4 or 6 weeks) versus the standard of care in the treatment of Gram-positive prosthetic hip joint infection with a…
- Trial name
- LIZ-BONE (NCT01757236)
- Testing
- VANCOMYCIN, CEFTRIAXONE, CLINDAMYCIN
- Where
- 9 sites in France, Italy and 1 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Colorectal Cancer
A Multi Center Study Comparing the Efficacy of CAD EYE and the Standard of Care (White Light )
This study is to assess the sensitivity and added benefits of CADEYE compared to standard care (white-light) in detecting colon polyps in patients undergoing colonoscopy.
- Trial name
- NCT05523271
- Testing
- CAD EYE (Computer Aided Diagnosis ----?
- Where
- Egypt
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.