Clinical trials: Sterility
Male Infertility
Proposed Research Protocol For Male Infertility
The purpose of this experiment is to test the feasibility of a minimally interventionist protocol for young couples with male factor infertility, which addresses the cause of infertility for these couples which is the inability…
- Trial name
- NCT01255397
- Testing
- Male Infertility Protocol
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infertility
Follicular Flushing Outcomes in Singles Versus Double Lumen Oocyte Retrieval Needles in Poor Responding Patients
In this study, the investigators aimed to evaluate to the efficacy of the needle type used in follicular flushing in oocyte retrieval in the poorest responders undergoing IVF.
- Trial name
- needles(opu) (NCT02391155)
- Testing
- single lumen needle in oocyte retrieval, double lumen needle in oocyte retrieval
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infertility
Results Following the Vitrification of Human Oocytes Using 2 Methodologies
The investigators are going to compare embryo developmental rates of human eggs following freezing in two different freezing methods.
- Trial name
- NCT01033474
- Where
- Peru
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwest Center for Reproductive Sciences
Infertility
Intrauterine G-CSF Administration in RIF
Aim of this study is to investigate the effects of intrauterine G-CSF on endometrial thickness, clinical pregnancy rate and live birth rate in a recurrent implantation failure (RIF) group
- Trial name
- G-CSF (NCT03783208)
- Testing
- G-CSF, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Gurgan Clinic
Infertility, Female
Transcriptomic Evaluation of Endometrial Receptivity
The purpose of this study is to comprehensively evaluate the transcriptomic signal of the endometrium before, during, and after the window of receptivity.
- Trial name
- NCT04141085
- Testing
- Endometrial biopsy
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Male Infertility
Relationship Between Nitric Oxide (NO) in Follicular Fluid and Sperm Fertilization Ability
Several studies indicate that Nitric Oxide (NO) plays an important role in the physiology of the reproductive system in mammals.
- Trial name
- NCT03307655
- Testing
- Control (fertile semen donors), Patients (subfertile men)
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- IVI Murcia
Infertility, Male Factor
FemaSeed LOCAL Artificial Insemination Trial
Brief Summary: The objectives of the trial are to evaluate the safety and effectiveness of the FemaSeed Localized Directional Insemination for artificial insemination, now known as the FemaSeed Intratubal Insemination since FDA…
- Trial name
- LOCAL (NCT04968847)
- Testing
- FemaSeed Localized Directional Insemination
- Where
- 18 sites in United States
- Volunteers
- 314 people, healthy volunteers welcome
- Sponsor
- Femasys Inc.
Infertility
Study of Free DNA Content of Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment
Study of Cell Free DNA Content of Human Embryo Culture Medium as a Non-Invasive Tool for Embryo Assessment in intra cytoplasmic sperm injection Treatment Cycles.
- Trial name
- NCT02480491
- Testing
- measuring cell freeDNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sadat City University
Primary Infertility, Secondary Infertility
Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF
The purpose of this study to evaluate a low cost minimal stimulation protocol combined with Intravaginal Culturing, to make IVF affordable and available across the large infertile/subfertile population
- Conditions
- Primary Infertility, Secondary Infertility, Low Responders, Mild to Moderate Male Factor Infertility
- Trial name
- MSP-INVO IVF (NCT01058252)
- Testing
- INVOCell, Letrozole 2.5 mg, recFSH 75 IU, STEP-3: LH Suppression & Monitoring, STEP-4: HCG Timing
- Where
- 2 sites in Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Galaxy Pharma (Pvt) Limited
Infertility Due to Azoospermia
Role of Transrectal-ultrasound in Evaluation of Azoospermia
Azoospermia is a word meaning to ejaculates with no spermatozoa without a definite underlying cause .1% of men has azoospermia, representing nearly 10 to 15% of all infertile men.
- Trial name
- NCT05026190
- Testing
- transrectal ultrasound
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Women Who Suffer From Hydrosalpinx That is Causing Infertility and Whom Want a Safer Way of Treamtent
Use of Essure® Micro-inserts in Women With Hydrosalpinx Prior to In Vitro Fertilization: A Prospective, Multicenter, International Feasibility Study
The purpose of this study is to gather safety data related to the use of Essure® micro-inserts in women with hydrosalpinx prior to in vitro fertilization and during pregnancy and to collect data with regard to implantation rates…
- Trial name
- NCT01221974
- Testing
- Essure Micro Insert
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Reproductive Science Center
Infertility
Study of Gene Associations and Infertility
The purpose of this this study is to use DNA screening strategies to identify genes and localize genomic regions that are differentially expressed in patients with infertility to further understand the genetic basis for…
- Trial name
- NCT01223092
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Sterility, Reproductive
Age-dependent Changes in the Responsiveness of Hypothalamic Pituitary Gonadal Axis in Men
The present study was designed to assess the responsiveness of the hypothalamic pituitary gonadal axis to kisspeptin administration with increasing age in men.
- Trial name
- NCT03315325
- Testing
- Human kisspeptin-10 (metastin 45-54)
- Where
- Pakistan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Quaid-e-Azam University
Infertility
The Pharmacokinetic and Bioavailability of GenSci094 Before and After a Change in Manufacturing Site
The bioavailability study is intended to evaluate the pharmacokinetic (PK) characteristics and the bioavailability of the two formulations in humans before and after the change of production site, in order to assess the possible…
- Trial name
- NCT06095206
- Testing
- GenSci094
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Spermatogenesis and Semen Disorders, Infertility, Male
Evaluation of FPT-20 for the Treatment of Spermatogenesis and Semen Disorders
This clinical study aims to evaluate the efficacy and safety of a novel, natural-derived formulation (FPT-20) in supporting spermatogenesis.
- Trial name
- NCT05399212
- Testing
- FPT-20
- Where
- Vietnam
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.
Pregnancy Related, Pre-Eclampsia
Natural Versus Programmed Frozen Embryo Transfer (NatPro)
NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed…
- Trial name
- NatPro (NCT04551807)
- Testing
- Modified natural cycle, Programmed cycle
- Where
- 15 sites in United States
- Volunteers
- 788 people, healthy volunteers welcome
- Sponsor
- JHSPH Center for Clinical Trials
Myopia
Phase 1 Study of SHJ002 Sterile Ophthalmic Solution in Pediatric Subjects
This is a single-center, open-label, first-in-human dose-escalation study of SHJ002 Ophthalmic Solution in children. (Part 1) Three (3) subjects will receive each concentration of SHJ002 for 3 days in an escalation design in one…
- Trial name
- NCT04928144
- Testing
- SHJ - Low concentration, SHJ - Mid concentration, SHJ - High concentration
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Sunhawk Vision Biotech, Inc.
Female Infertility
Extended Culture of Day 3 to Day 5 Frozen Thawed Day 3 Embryos Versus Day 5 Frozen-Thawed Embryos
Cryopreservation of embryos and oocytes has become routine in assisted reproduction technology (ART). Live birth rates following frozen embryo transfers have increased significantly.
- Trial name
- NCT05858333
- Testing
- Extended culture for Group 2: (day 3-5 group)
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Infertility
Can Pregnancy be Predicted According to ATR-FTIR Spectrophotometry of Incubation Medium of Embryos in IVF
The aim of this study is to examine the variability of culture media composition based on the ATR-FTIR (Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy) technique on the day of embryo transfer/vitrification.
- Trial name
- NCT03317418
- Testing
- ATR-FTIR Spectrophotometry
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility Female
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Poor ovarian response (POR) is one of the major therapeutic challenges in in vitro fertilization. Several therapeutic approaches for POR have been explored; yet, a single effective strategy has not yet been established.
- Trial name
- NCT02498210
- Testing
- In Vitro Maturation Procedure
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.