Clinical trials: Stricture Recurrence
Coronary Restenosis
Drug-eluting Stents vs. Drug-coated Balloon for Preventing Recurrent In-stent Restenosis
The purpose of this study is to establish the safety and effectiveness of paclitaxel eluting balloon (SeQuent Please) compared to coronary stenting with the Everolimus-eluting balloon expandable stent (Xience Prime or Xience…
- Trial name
- RESTORE (NCT01967199)
- Testing
- Everolimus-eluting balloon expandable stent, paclitaxel eluting balloon
- Where
- 11 sites in South Korea
- Volunteers
- 175 people
- Sponsor
- Seung-Jung Park
Stricture Urethra
Role of Paclitaxel in Stricture Urethra
Stricture urethra is a common disease and has various causing factors. The most common performed procedure is direct visual internal urethrotomy (DVIU), but unfortunately has a high recurrence rates.
- Trial name
- NCT05678413
- Testing
- DVIU with paclitaxel injection, DVIU
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al-Azhar University
Degenerative Disc Disease, Spondylolisthesis
The European Robotic Spinal Instrumentation (EUROSPIN) Study
In a multinational prospective study, preoperative, intraoperative, perioperative and follow-up data on patients receiving thoracolumbar pedicle screw placement for degenerative disease or infections or tumors will be collected.
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis, Recurrent Disc Herniation
- Trial name
- EUROSPIN (NCT03398915)
- Testing
- Transpedicular Instrumentation
- Where
- 12 sites in Austria, France and 5 more
- Volunteers
- 932 people
- Sponsor
- Marc Schröder
Stricture Urethra
The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence
The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence
- Trial name
- prp vs VIU (NCT07837167)
- Testing
- PRP injection, VIU
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Ischemic Stroke
Stenting vs. Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis
PRIMARY HYPOTHESIS: Compared with intensive medical therapy alone, intracranial angioplasty and stenting combined with intensive medical therapy will decrease the risk of the primary endpoint by 35% over a mean follow-up of two…
- Trial name
- SAMMPRIS (NCT00576693)
- Testing
- intracranial angioplasty and stenting, intensive medical management
- Where
- 50 sites in United States
- Volunteers
- 451 people
- Sponsor
- Medical University of South Carolina
Brachiocephalic Vein Stenosis
Biomimetic Stent and Drug Eluting Balloon to Treat Recurrent Cephalic Arch Stenosis
The study evaluates the use of a biomimetic stent (SUPERA®) and a drug eluting balloon (DEB - Passeo 18 Lux) for the treatment of recurrent and tight cephalic arch stenosis in patients with brachiocephalic fistulas.
- Trial name
- Arch-V (NCT03891693)
- Testing
- Passeo-18 Lux and SUPERA® stent
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Singapore General Hospital
Non-GCB/ABC Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma
Tislelizumab in Combination With Lenalidomide in Refractory and Relapsed Elderly Patients With Non-GCB DLBCL
Aim of this study will evaluate the efficacy and safety of tislelizumab in combination with lenalidomide in in patients with relapsed or refractory Elderly Patients with non-GCB Diffuse Large B Cell Lymphoma
- Conditions
- Non-GCB/ABC Diffuse Large B-Cell Lymphoma, High-grade B-cell Lymphoma, Follicular Lymphoma Grade IIIb, Transformed Lymphoma
- Trial name
- NCT04796857
- Testing
- PD-1 Antibody, Lenalidomide
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Huiqiang Huang
Surgery, Brain Tumor
Neurosurgical Transitional Care Programme
Readmissions increasingly serve as a metric of hospital performance, inviting quality improvement initiatives in both medicine and surgery.
- Conditions
- Surgery, Brain Tumor, Brain Tumor, Recurrent, Brain Pathology
- Trial name
- TCP (NCT03593330)
- Testing
- Transitional Care Programme
- Where
- United Kingdom
- Volunteers
- 242 people
- Sponsor
- Barts & The London NHS Trust
Intestinal Failure, Catheter-Related Bloodstream Infection (CRBSI) Nos
Catheter Salvage in Intestinal Failure Patients
This is an observational study evaluating a catheter salvage strategy in relation to catheter-related bloodstream infections in patients with chronic intestinal failure dependent on home parenteral support.
- Trial name
- NCT03222232
- Testing
- catheter salvage
- Where
- Denmark
- Volunteers
- 715 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
COX-2 Inhibitor, Meloxicam
Can COX-2 Inhibitor Decrease Stricture Recurrence After Direct Vision Internal Urethrotomy?
To evaluate the efficacy and safety of nonsteroidal anti-inflammatory drugs (NSAIDs) in preventing urethral stricture recurrence after direct visual internal urethrotomy.
- Conditions
- COX-2 Inhibitor, Meloxicam, Stricture Recurrence, Direct Vision Internal Urethrotomy
- Trial name
- NCT06697106
- Testing
- Nonsteroidal anti-inflammatory drugs
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- New Valley University
Cerebrovascular Disease
Cilostazol-Aspirin Therapy Against Recurrent Stroke With Intracranial Artery Stenosis
Multi-center, open-labelled randomized controlled trial, to study the effect of aspirin plus cilostazol and aspirin alone on the progression of intracranial arterial stenosis, in 200 chronic stroke patients with 50-99% stenosis…
- Trial name
- NCT00333164
- Testing
- Asprin, Cilostazol
- Where
- Japan
- Volunteers
- 200 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Bilateral Limb Ischemic Preconditioning, Intracranial Arterial Stenosis
Feasibility, Safety and Efficacy of Remote Ischemic Preconditioning for Symptomatic Intracranial Arterial Stenosis in Octogenarians
Making a limb transiently ischemic induces ischemic tolerance in distant organs such as the heart. This study aims to evaluate the feasibility, safety and initial efficacy of using briefly repetitive bilateral limb ischemic…
- Trial name
- NCT01570231
- Testing
- bilateral limb ischemic preconditioning (Doctormate, IPC-906X)
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Ji Xunming
Esophageal Neoplasm, Anastomotic Leak
Prediction of Anastomotic Complications and Recurrent Laryngeal Nerve Injury Based on Postoperative Early Endoscopic Evaluation
Analyze the correlation between the conformity of the anatomy (based on endoscopic examination) and postoperative anastomotic fistula and anastomotic stenosis; establish an anastomotic classification; and construct a predictive…
- Conditions
- Esophageal Neoplasm, Anastomotic Leak, Recurrent Laryngeal Nerve Injuries, Anastomotic Stenosis
- Trial name
- NCT06348381
- Testing
- No intervention
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Shanghai Chest Hospital
Vertebral Artery Stenosis
Drug Eluting Stenting and Short Dual Antiplatelet Therapy for Preventing Recurrent Stroke in Vertebral Stenosis Registry Study
This is a prospective, multi-center, registry study exploring the duration of dual antiplatelet therapy (DAPT) after drug-eluting stent(DES) treatment of symptomatic vertebral artery atherosclerotic stenosis.
- Trial name
- M Short DAPT (NCT06683300)
- Testing
- DAPT for 3 months after vertebral artery stenting
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Beijing Tiantan Hospital
Urethral Stricture
Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past…
- Trial name
- NCT04357080
- Testing
- Urethroplasty
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Al-Azhar University
Ischemic Cerebral Infarction
Ongericimab Injection Reducing Recurrence of Ischemic Stroke
The Oris trial aims to evaluate whether the use of Ongericimab injection in patients with atherosclerotic ischemic cerebrovascular disease within 3 months of onset can reduce the risk of recurrent major cardiovascular events by…
- Trial name
- ORIS (NCT07242599)
- Testing
- High target group, Low target group
- Where
- 199 sites in China
- Volunteers
- 4,810 people
- Sponsor
- Beijing Tiantan Hospital
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Esophageal Stricture
INGEST I Pilot Study
INGEST I Pilot study is a feasibility study for evaluating the safety and efficacy of DCBs.
- Trial name
- INGEST (NCT03885310)
- Testing
- GIE Drug Coated Balloon
- Where
- Paraguay
- Volunteers
- 9 people
- Sponsor
- GIE Medical
High Resolution Vessel Wall Imaging, Recurrent Stroke
Plaque Characteristics Predict Recurrent Stroke in MCA Stroke Patients
The epidemiology of TOAST classification in Asian patients seems to differ due to the higher rates of large-artery atherosclerosis.
- Conditions
- High Resolution Vessel Wall Imaging, Recurrent Stroke, Stroke, Mechanism, Atheroscleroses, Intracranial
- Trial name
- NCT06404242
- Where
- Vietnam
- Volunteers
- 75 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Coronary Artery Disease, Arteritis
National Multicenter Cohort Registry Study of Rapid rEcurrences of Coronary Unexplained In-stent Restenosis
This project aims to establish a clinical cohort and diagnostic assessment framework by conducting a national multicenter cohort registry study.
- Conditions
- Coronary Artery Disease, Arteritis, In-Stent Stenosis (Restenosis) of Coronary Artery Stent
- Trial name
- RECUR Registry (NCT05437965)
- Testing
- Treatment made by experienced clinicians
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases