Clinical trials: Stroke, Chronic
Spinal Cord Injuries, Nerve Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional…
- Conditions
- Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia
- Trial name
- NCT04144972
- Testing
- Medtronic Summit RC+S or Percept RC
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Francisco
Stroke, Chronic Stroke
Neural Operant Conditioning
The goal of this clinical trial is to learn if operant conditioning can reduce spasticity in order to improve walking in stroke patient.
- Conditions
- Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic
- Trial name
- NCT06113965
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Stroke
Effect of the Dose of Training in Upper Limb Motor Recovery After Stroke.
The aim of the study is to analyse the effect of intensive training on upper limb function in stroke patients. 20 stroke patients were randomly divided into two groups: the intensive group and the control group.
- Trial name
- NCT06571292
- Testing
- Intensive training with robotic exoskeleton for upper limbs, Task specific training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Hemiparesis of the Upper Limb Following Stroke
MyndMove Therapy for Severe Hemiparesis of the Upper Limb Following Stroke
The purpose of this study is to examine the efficacy of MyndMove therapy in the early sub-acute, late sub-acute and chronic post-stroke patients.
- Trial name
- NCT02266836
- Testing
- MyndMove
- Where
- 6 sites in Canada
- Volunteers
- 50 people
- Sponsor
- MyndTec Inc.
Stroke Sequelae, Gait Disorders, Neurologic
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation.
- Conditions
- Stroke Sequelae, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT06593184
- Testing
- Trans-spinal magnetic stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Stroke
Primed vs. Unprimed rTMS in Chronic Stroke
The goal of stroke rehabilitation is to restore function to the weak side of the body. However, this is often a difficult task to accomplish due to not only to damage from the stroke, but from increased excitability in the…
- Trial name
- NCT01757821
- Testing
- real 6-Hz primed low-frequency rTMS, real 1-Hz rTMS only
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Chronic Stroke
ANIMATOR - RehUP BCI Controlled Robotic Therapy vs. an Attention-based Control
ANIMATOR aims to examine how BCI therapy vs. attention based control therapy can be used to treat people in the chronic phase of stroke with moderate to severe upper extremity impairment.
- Trial name
- ANIMATOR (NCT06538506)
- Testing
- RehUp BCI Intervention, Control Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Chronic Troublesome Sialorrhea, Cerebral Palsy
Clinical Study to Investigate the Efficacy and Safety of NT 201 Compared to Placebo in the Treatment of Chronic Troublesome Drooling Associated With Neurological Disorders and/or Intellectual Disability
The objective of this study is to investigate the efficacy and safety of NT 201 compared with placebo for the treatment of chronic troublesome sialorrhea associated with neurological disorders (e.g.
- Conditions
- Chronic Troublesome Sialorrhea, Cerebral Palsy, Stroke, Traumatic Brain Injury
- Trial name
- SIPEXI (NCT02270736)
- Testing
- NT 201
- Where
- 31 sites in Georgia, Hungary and 4 more
- Volunteers
- 256 people
- Sponsor
- Merz Pharmaceuticals GmbH
Stroke, Proprioceptive Disorders
Effects of Proprioceptive Activities on Hand Function in Chronic Stroke Patients
To determine effects of proprioceptive activities on hand function in chronic stroke patients
- Trial name
- NCT05087719
- Testing
- experimental group, conventional treatment
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Atrial Fibrillation and Flutter, Stroke
The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on Dialysis
The study aims to evaluate the appropriateness of initiating oral anticoagulation for stroke risk reduction in dialysis populations with atrial fibrillation.
- Conditions
- Atrial Fibrillation and Flutter, Stroke, Major Bleed, End-stage Renal Disease
- Trial name
- DANWARD (NCT03862859)
- Testing
- Warfarin
- Where
- 13 sites in Denmark
- Volunteers
- 718 people
- Sponsor
- Nicholas Carlson
Cognition Disorders
Robotics Plus VR in Improving Cognition
Stroke can be classified as ischemic, i.e. due to the lack of blood flow, and haemorrhagic, caused by bleeding. Stroke results in focal signs and symptoms, with a devastating impact on a patient and his family.
- Trial name
- NCT03914313
- Testing
- Robotic Treatment plus VR
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Myocardial Infarction, Cerebral Infarction
Acute Myocardial Infarction and Acute Cerebral Infarction (AMIAC) Registry and Follow-up
A registry of consecutive patients who were admitted and diagnosed with acute myocardial infarction or acute cerebral infarction were conducted at the Guangdong General Hospital or the First Affiliated Hospital of Guangzhou…
- Conditions
- Myocardial Infarction, Cerebral Infarction, Chronic Kidney Diseases, Mortality
- Trial name
- AMIAC (NCT03166696)
- Where
- 3 sites in China
- Volunteers
- 30,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Stroke
Transcranial Direct Current Stimulation for Post-Stroke Aphasia
This is a randomized, crossover design trial that will compare how anodal transcranial direct current stimulation (tDCS) versus sham tDCS administered during multiple sessions of scripting therapy affects the acquisition and…
- Trial name
- NCT02461355
- Testing
- Aphasia therapy, Anodal tDCS
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Columbia University
Stroke, Cerebrovascular Accident
Enhancing Plasticity in Stroke Patients With Severe Motor Deficit
This study will evaluate the effectiveness of sustained peripheral nerve stimulation coupled with functional motor training, to improve hand motor function in poorly recovered stroke patients.
- Trial name
- NCT02633215
- Testing
- S88 Dual Output Stimulator by Grass Technologies
- Volunteers
- 36 people
- Sponsor
- Lumy Sawaki
Congenital Hemiparesis
Comparing the Location of the Motor Cortex in Children Using Two Methods
Hypothesis: In typically developing children (TDC), use of conventional EEG landmarks to determine the brain area that controls hand function will not differ from TMS-guided determination of individual motor hotspots.
- Trial name
- NCT02015338
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke
Acute Effects of Whole Body Vibration in Chronic Stroke
Whole body vibration has been found to be useful in promoting bone health, balance, and muscle performance in older adults. The overall aim of the proposed study is to determine whether whole body vibration (WBV) has immediate…
- Trial name
- NCT01211093
- Testing
- High frequency whole body vibration, Low frequency whole body vibration, control
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Ischemic
Effect of Transcutaneous Vagus Nerve Stimulation on Upper Limb Function in Stroke Patients
The goal of this interventional study is to investigate the therapeutic efficacy of non-invasive vagus nerve stimulation on upper limb function in chronic stroke patients .
- Trial name
- NCT06048055
- Testing
- Transcutaneous auricular vagus nerve stimulation, selected physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Aphasia, Cerebrovascular Accident
Role of the Right Brain in Recovery of Language Function in Chronic Stroke
This study will examine in healthy individuals and in patients with aphasia (a language disturbance that is usually caused by stroke, brain disease, or injury) which parts of the brain are involved in naming everyday objects.
- Trial name
- NCT00076479
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cerebrovascular Disorders, Cerebral Stroke
Using Repetitive Transcranial Magnetic Stimulation (rTMS) in the Rehabilitation of Chronic Spatial Neglect After Stroke
Visuospatial neglect is a common neurological symptom which appears following strokes on regions of the right hemisphere of the brain.
- Conditions
- Cerebrovascular Disorders, Cerebral Stroke, VISIO-spatial Neglect, VISUO-spatial Extinction
- Trial name
- NEGLECT (NCT01000103)
- Testing
- Real rTMS
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Clinical Efficacy of Luna EMG Robot Therapy for Patients After Stroke
A lot of studies prove that rehabilitation with the use of modern devices accelerates the recovery of function in patients after stroke.
- Trial name
- NCT03888118
- Testing
- Luna EMG
- Volunteers
- 60 people
- Sponsor
- Rehamed Center
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