Clinical trials: Stroke Risk
Cardiovascular Diseases, Heart Diseases
The North Kynouria Project
The North Kynouria Project was initiated to study cardiovascular/stroke risk factors by employing mass screening and long-term surveillance of an adult population in the municipality of North Kynouria, in the county of Arcadia…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Disease, Coronary Disease
- Trial name
- NCT06115213
- Testing
- Patient counselling
- Where
- Greece
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ioannina
Stroke
Genetic and Environmental Risk Factors for Hemorrhagic Stroke
The purpose of this study is to find risk factors for hemorrhagic stroke.
- Trial name
- GERFHS (NCT00682695)
- Where
- 7 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Cardiovascular Diseases, Fatty Liver
Ultrasound Assessment of Atherosclerotic Plaque Burden and Cardiovascular Risk: A 10-Year Prospective Study
The P-SONAR study is a large, observational, prospective cohort study. The overall aim of the study is to investigate whether plaque burden estimation by 2D ultrasound of the carotid and femoral arteries may enhance…
- Conditions
- Cardiovascular Diseases, Fatty Liver, Atherosclerosis of Femoral Artery, Carotid Artery Plaque
- Trial name
- P-SONAR (NCT06933745)
- Where
- Norway
- Volunteers
- 21,029 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Carotid Artery Plaque, Carotid Web
Atherosclerotic Plaque Characteristics Associated With a Progression Rate of the Plaque in Carotids and a Risk of Stroke
Atherosclerosis is the most common cause of stroke. The aims of the project are to compare the visual and digital analysis of sonographic images of atherosclerotic plaque in carotids in vivo, in vitro and with a histological…
- Trial name
- ANTIQUE (NCT02360137)
- Where
- Czechia
- Volunteers
- 1,863 people, healthy volunteers welcome
- Sponsor
- University Hospital Ostrava
Essential Hypertension, Cardiovascular Disease
Prognostic Value of the Circadian Pattern of Ambulatory Blood Pressure for Multiple Risk Assessment
The HYGIA study was designed to investigate prospectively 1. the prognostic value of ambulatory blood pressure (BP) monitoring among subjects primarily evaluated at primary care settings 2.
- Conditions
- Essential Hypertension, Cardiovascular Disease, Stroke, Chronic Kidney Disease
- Trial name
- HYGIA (NCT00741585)
- Testing
- Any antihypertensive medication alone or in combination, Ambulatory blood pressure monitoring
- Where
- 20 sites in Spain
- Volunteers
- 21,983 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Preeclampsia, Eclampsia
Cardiac Biomarkers in Preeclampsia: Prediction of Disease and the Risk of Future Cardiovascular Events in Survivors
SUMMARY Background: Improvements in the management and prevention of obstetric haemorrhage and sepsis, in addition to magnesium sulphate for preeclampsia have led to significant reduction in global maternal mortality rates; thus…
- Trial name
- PreeclampBIO (NCT04468763)
- Where
- Nigeria
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Babcock University
Acute Ischemic Stroke
Dynamic Changes in Human Microbiome Predict the Risk of Adverse Outcomes in Patients With Acute Ischemic Stroke: a Multicenter Prospective Cohort Study
(1) The main purpose To explore the predictive value of human microbiome and its metabolome for adverse prognosis in patients with acute ischemic stroke (AIS). (2) Secondary purposes 1.
- Trial name
- NCT06240468
- Testing
- not have
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Zhujiang Hospital
Stroke, Ischemic
Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have…
- Trial name
- CHAMPS-TR (NCT06479174)
- Testing
- CHAMPS-TR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Death, Stroke
Postoperative Atrial Fibrillation and Long-term Survival
The aim of the investigators trial was to evaluate association between new onset postoperative atrial fibrillation (POAF) and late cardiovascular morbidity and mortality.
- Conditions
- Death, Stroke, Myocardial Infarction
- Trial name
- POAF (NCT02349269)
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- Kuopio University Hospital
Type 2 Diabetes, Coronary Heart Disease
NMR Metabolomics-Based Risk Assessment and Stratified Digital Health Interventions in Middle-Aged Adults (PREMAP)
PREMAP invites residents of the Eloisa region (South Savo, Finland) turning 45, 50, or 55 years of age in 2026 to undergo a blood-based NMR metabolomics risk assessment for five interlinked cardio-renal-metabolic conditions (type…
- Conditions
- Type 2 Diabetes, Coronary Heart Disease, Myocardial Infarction, Cerebrovascular Disease
- Trial name
- PREMAP (NCT07820800)
- Testing
- Digital health interventions
- Where
- Finland
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
MACE, Atrial Fibrillation (AF)
throMboembolic Risk Associated To High atrIal Fibrillation riSk
Cardiovascular diseases are the leading cause of mortality from treatable conditions in the European Union and the second from preventable causes, with a standardized mortality rate of 257.8 deaths per 100,000 inhabitants.
- Conditions
- MACE, Atrial Fibrillation (AF), Quality-adjusted Life-years, Electronic Health Records
- Trial name
- MATHIAS (NCT07441759)
- Testing
- AI_MATHIAS
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Coronary Heart Disease, Stroke
Hamburg City Health Study - a German Cohort Study
The Hamburg City Health Study (HCHS) is a large, prospective, long-term, population-based cohort study and a unique research platform and network to obtain substantial knowledge about several risk and prognostic factors in major…
- Conditions
- Coronary Heart Disease, Stroke, Dementia, Cancer
- Trial name
- HCHS (NCT03934957)
- Where
- Germany
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stroke, Cardiovascular Diseases
Effectiveness of Stroke Riskometer Apps In Improving Awareness and Stroke Risk Probability
This intervention study using the Stroke Riskometer Apps as health promotion and disease prevention tools for the stroke prevention.
- Conditions
- Stroke, Cardiovascular Diseases, Risk Factor, Cardiovascular
- Trial name
- NCT04529681
- Testing
- Stroke Riskometer Application, Informational Leaflets
- Where
- Malaysia
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Stroke Not Otherwise Specified, Control Condition
Vessel Angles and Diameters in Stroke Disease
Retrospective analysis of internal carotid artery morphology on CT angiography images of patients with acute ischemic stroke.
- Trial name
- NCT06756724
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Non-valvular Atrial Fibrillation
Observe the Safety and Effectiveness of the WATCHMAN FLX™ for Subjects in Hong Kong
The primary objective of this study is to observe the safety and effectiveness of the WATCHMAN FLX™ Left Atrial Appendage Closure (LAAC) Device for subjects with non-valvular atrial fibrillation to reduce the risk of stroke in…
- Trial name
- NCT04096963
- Testing
- The WATCHMAN FLX Delivery System
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Boston Scientific Corporation
Cerebral Small Vessel Diseases
Retinal, Cerebral and Vascular Precursor Markers of Cerebral Small Vessel Disease.
Cognitive impairment and dementia are primarily due to a combination of vascular brain injury and neurodegenerative lesions. The vascular component is now recognized as a major contributor to the pathophysiology of dementia, with…
- Trial name
- SHIVA-SHARE (NCT05305144)
- Testing
- Vascular and ophthalmological examinations
- Where
- France
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Hypertension (HTN), Vascular Diseases
The BASIC-S Feasibility Study for Vascular Risk Reduction
Vascular risk factors drive stroke, heart disease, and dementia, but translating lifestyle guidelines into routine clinical care remains challenging.
- Conditions
- Hypertension (HTN), Vascular Diseases, Stroke, Dementia
- Trial name
- BASIC-S (NCT07755631)
- Testing
- BASIC-S Intervention, Standard / Usual Care
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Andrew Appleton
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III