Clinical trials: Strokes
Stroke
Exercise Intensity Matters in Stroke Rehabilitation
The main objective of this multi-site project is to compare the effects of 12 weeks of HIIT vs. MICT on brain plasticity. The effects of HIIT vs.
- Trial name
- NCT03614585
- Testing
- 12 weeks of High-intensity Interval Training, 12 weeks of Moderate-Intensity Continuous Training
- Where
- 2 sites in Canada
- Volunteers
- 80 people
- Sponsor
- McGill University
Stroke, Cerebrovascular Disorders
Stroke Treatment Associate to Rehabilitation Therapy and Transcranial DC Stimulation
The purpose of this study is to determine whether active stimulation of the affected hemisphere will be more effective than simulated current in treatment of stroke
- Conditions
- Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- START-tDCS (NCT02156635)
- Testing
- Transcranial direct current stimulation, Constraint-Induced Movement Therapy
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Paraíba
Foramen Ovale, Patent
Risk of Ischaemic Stroke After Pulmonary Embolism in Patients With and Without Patent Foramen Ovale
stroke's risk is increased in patients with pulmonary embolism and PFO compared to patients without PFO. Does this increased risk persist years after pulmonary embolism ?
- Trial name
- EPIC-FOPCohort (NCT04987008)
- Where
- 3 sites in France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Brest
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Ischemic Stroke
Amnis Therapeutics Thrombectomy Device-First in Man (FIM) Safety and Performance Study
Prospective, single-arm, open label, Safety and Performance clinical investigation.
- Trial name
- NCT02994563
- Testing
- Thrombectomy Device
- Where
- 4 sites in Spain, Sweden
- Volunteers
- 5 people
- Sponsor
- Amnis Therapeutics
Nervous System Disorders
Dysport® Adult Upper Limb Spasticity
The purpose of this research study is to assess the efficacy of Dysport compared to placebo in improving muscle tone in hemiparetic subjects with upper limb spasticity due to stroke or traumatic brain injury.
- Trial name
- NCT01313299
- Testing
- Botulinum toxin type A
- Where
- 40 sites in United States, Belgium and 7 more
- Volunteers
- 243 people
- Sponsor
- Ipsen
Ischemic Stroke
Hemodynamic Effects on Cerebral Autoregulation in Acute Stroke
This study investigates if there are hemodynamic alterations in acute stroke that predispose patients to impaired perfusion and regulation of cerebral blood flow.
- Trial name
- NCT02056821
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Henry Ford Health System
Stroke, Quality of Life
Association Between Fatigue Severity and Health-Related Quality of Life in Individuals With Stroke
This observational cross-sectional study aims to examine the association between fatigue severity and health-related quality of life in individuals with stroke.
- Conditions
- Stroke, Quality of Life, Post Stroke Fatigue
- Trial name
- NCT07498114
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Uskudar University
Chronic Stroke
An Open-labeled Phase II Study to Evaluate the Efficacy and Safety of GXNPC-1 in Patients with Chronic Stroke
The primary objective of this study is to evaluate the efficacy for subjects with chronic stroke after GXNPC-1 injection.
- Trial name
- NCT04088149
- Testing
- GXNPC1
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- Gwo Xi Stem Cell Applied Technology Co., Ltd.
Stroke
Effect of Allium Cepa in the Management of Shoulder Pain Post Stroke
One of the disabling consequences of stroke is hemipleic shoulder pain. Hemiplegic shoulder pain could be most important hinderance to upper extremity function after stroke .
- Trial name
- NCT03468049
- Testing
- Topical App. of Allium Cepa Extract, Phonophoresis of Allium Cepa Extract, Raw Mashed Allium Cepa Application
- Where
- Nigeria
- Volunteers
- 60 people
- Sponsor
- Bayero University Kano, Nigeria
Stroke, Aphasia
Enhancing Reading Recovery in Aphasia With tDCS and Phonomotor Therapy
This study is designed for individuals with aphasia, a language disorder that affects many stroke survivors, making it difficult to read, speak, and understand language.
- Trial name
- NCT06891638
- Testing
- Schedule of tDCS administration
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Kessler Foundation
Deglutition Disorders
Prevalence, Risk Factors and Complications of Oropharyngeal Dysphagia in Stroke Patients
Oropharyngeal dysphagia (OD) is a common morbidity after stroke that disrupts swallowing physiology. The investigators aimed at evaluating the prevalence of oropharyngeal dysphagia (OD) after stroke and analysing the risk factors…
- Trial name
- Marato-11 (NCT03147755)
- Testing
- No intervention
- Volunteers
- 395 people
- Sponsor
- Pere Clave
Atrial Fibrillation, Stroke
Canadian Community Utilization of Stroke Prevention Study - Emergency Department
Atrial fibrillation (AF) is a common heart condition, and increases the risk of stroke by six times. There are several medications (blood thinners) that can prevent strokes in AF patients.
- Trial name
- C-CUSP ED (NCT02358655)
- Testing
- Retrospective review of OAC prescription, Prescription of OAC in ED, Community AF clinic
- Where
- 5 sites in Canada
- Volunteers
- 360 people
- Sponsor
- Population Health Research Institute
Stroke
F@ce 2.0 - Information and Communication Technology-based Rehabilitation Intervention After Stroke in Sweden
The purpose of the present proposal is to implement and evaluate a new model for mobile phone supported and family-centred rehabilitation intervention (F@ce 2.0) with regard to functioning in activities in daily living and…
- Trial name
- NCT04351178
- Testing
- Mobile phone supported and team based rehabilitation, Rehabilitation as usual
- Where
- 12 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Karolinska Institutet
Stroke
Clinical Applicability of Robot-assisted Gait Training System in Acute Stroke Patients
Investigation of the clinical feasibility and efficacy of a newly developed robot-assisted gait training system for acute stroke survivors.
- Trial name
- NCT02755415
- Testing
- HIWIN Robotic Gait Training System, Static Standing Table
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Basilar Artery Occlusion, Posterior Circulation Brain Infarction
Cerebrolysin as an Add-On Therapy to Standard Treatment of Basilar Artery Occlusion
The standard therapy for acute ischemic posterior circulation stroke (PCS) often leads to poor functional outcomes and high mortality rates, despite all advances in reperfusion therapy.
- Trial name
- NCT06489925
- Testing
- Cerebrolysin
- Volunteers
- 20 people
- Sponsor
- University Hospital Sestre Milosrdnice
Carotid Artery Occlusion
Effectiveness of Surgical and Diagnostic Methods in Cerebral Vascular Occlusive Disease
This study attempts to improve surgical treatment outcomes among people with chronic carotid artery occlusive disease by conducting a comprehensive review of neuroradiological, clinical, and cognitive data.
- Trial name
- NCT07396025
- Testing
- Revascularization/Conservative management
- Where
- Kazakhstan
- Volunteers
- 60 people
- Sponsor
- National Centre for Neurosurgery, Republic of Kazakhstan
Stroke
Task-Oriented Upper Limb Training With Focal Vibration in Stroke
This study aims to investigate the effects of task-oriented upper limb training combined with focal vibration on hand function, proprioception, and muscle tone in patients with stroke.
- Trial name
- NCT07558876
- Testing
- Task-oriented upper limb training combined with focal vibration, Active Comparator: Task-Oriented Upper Limb Training Alone
- Where
- 2 sites in South Korea
- Volunteers
- 38 people
- Sponsor
- Jisu Kim
Stroke, Chronic Stroke
Effects of Different Doses of Virtual Reality Therapy in Chronic Stroke Patients
This study aimed to compare the effects of different doses of Wii Fit-based virtual reality (VR) therapy added to conventional rehabilitation in patients with chronic stroke.
- Trial name
- NCT07656987
- Testing
- Wii Fit-Based Virtual Reality Balance Training, Conventional Physiotherapy and Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Chronic Stroke
Dyadic Interventions to Boost Quality of Life Among Stroke Survivors and Care Partners in Pakistan.
This study (RCTs) will be conducted on stroke survivors and their care partners after discharge from the hospital. The study will aim to evaluate the impact of augmented dyadic intervention on the quality of life of stroke…
- Trial name
- NCT06827093
- Testing
- Skill Building Dyadic Intervention
- Where
- China
- Volunteers
- 392 people
- Sponsor
- Zhengzhou University
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