Clinical trials: Strokes
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1)
Currently, early reperfusion is considered as the most effective therapy for the treatment of acute ischemic stroke (AIS). Over the past 20 years, intravenous tissue plasminogen activator (IV tPA) has been demonstrated to be the…
- Trial name
- NCT03210051
- Testing
- Remote ischemic conditioning, Endovascular treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Stroke, Brain Injuries
Neuroprotective Study of Electroacupuncture Pretreatment in Patients Undergoing Cardiac Surgery
The purpose of this study is to evaluate the neuroprotective effect of electroacupuncture pretreatment in patients undergoing cardiac surgery as an preventive sequela in a randomized and controlled clinical trial.
- Trial name
- NCT01020266
- Testing
- non electroacupuncture stimulation, Electroacupuncture pretreatment
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Stroke
Soft Robot for Rehabilitation of Hand Function After Stroke
The goal of this clinical trial is to investigate the feasibility of using the Soft Forearm Robot system for wrist and forearm recovery of hemiplegic subjects suffered from stroke.
- Trial name
- NCT07329075
- Testing
- new soft robotic glove
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke
Recanalization and Stenting for Non-acute Veterbrobasilar Artery Occlusion
To evaluate whether recanalization and stenting for symptomatic subacute and chronic veterbrobasilar artery occlusion is technically feasible, can prevent from recurrent ischemic events and promotes functional recovery of…
- Trial name
- NCT01632865
- Testing
- stenting
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Zhengzhou University
Stroke, Intracranial Stenosis
Characterizing Hemodynamic Compensation in Patients With Intracranial Stenosis
The overall aim of this work is to assess the relationship between stroke risk and hemodynamic compensation strategies, as measured using a novel 3.0 Tesla MRI protocol, in patients with symptomatic intracranial (IC)…
- Trial name
- VAMMPRIS (NCT02506907)
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Vanderbilt University
Stroke, Hemiplegia
Visual and Auditory Electromyography Biofeedback Among Stroke Patients
Stroke commonly results in impairments of balance, mobility, and lower extremity motor function that limit independence in daily activities.
- Conditions
- Stroke, Hemiplegia, Stroke Rehabilitation
- Trial name
- NCT07710937
- Testing
- Visual Electromyography Biofeedback, Auditory Electromyography Biofeedback, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- University of Lahore
Brain Injuries, Stroke
Telerehabilitation in Severe Acquired Brain Injury
We will investigate the use of TR, based on advanced Information and Communication Technology (ICT) solutions, taking into account that the supervision of rehabilitation at home will be enriched with the counselling and vital…
- Trial name
- NCT03709875
- Testing
- TR Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Stroke, Paralysis Arm
PNS Motor Stimulation Study
Paralysis is one of the most disabling features of Spinal cord injury and stroke. In select cases, where the nerve is intact, stimulation can achieve meaningful muscle contraction e.g. to restore grip and release function.
- Conditions
- Stroke, Paralysis Arm, Spinal Cord Injury
- Trial name
- NCT07810712
- Testing
- Stimulation of the motor unit
- Where
- United Kingdom
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Walton Centre NHS Foundation Trust
Stroke, Self Efficacy
Visual Arts-based Intervention for Community-dwelling Stroke Survivors
Stroke is the major cause of disability worldwide and leads to psychosocial issues for community-dwelling stroke survivors in their recovery journey.
- Conditions
- Stroke, Self Efficacy, Psychosocial Problem
- Trial name
- NCT06395857
- Testing
- Visual arts-based intervention
- Where
- Macau
- Volunteers
- 32 people
- Sponsor
- The Nethersole School of Nursing
Stroke
Robotic Rehabilitation and Cognitive Functions
A recent multicenter study of the Fondazione Don Gnocchi (FDG) Robotic Rehabilitation Group (NCT02879279) showed the efficacy of robotic rehabilitation in upper limb motor recovery after stroke using a set of robots and…
- Trial name
- NCT04164381
- Testing
- Robotic assisted intervention
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Acute Ischemic Stroke
ANAIS Study to Confirm the Safety and Performance of the ANA 5F Advanced Neurovascular Access®
Prospective, single-arm, multi-center study to assess the safety and performance of the ANA 5F Advanced Neurovascular Access®, in combination with a stent retriever in patients with acute ischemic stroke.
- Trial name
- ANAIS (NCT05409430)
- Testing
- Neurothrombectomy
- Where
- 3 sites in Spain
- Volunteers
- 43 people
- Sponsor
- Anaconda Biomed S.L.
Cardiovascular Disease, Peripheral Arterial Disease
Treatment of HDL to Reduce the Incidence of Vascular Events HPS2-THRIVE
The primary aim is to assess the effects of raising HDL cholesterol (the good type) with extended release niacin/laropiprant 2g (previously known as MK-0524A) versus matching placebo on the risk of heart attack or coronary death…
- Conditions
- Cardiovascular Disease, Peripheral Arterial Disease, Diabetes Mellitus, Coronary Heart Disease
- Trial name
- HPS2-THRIVE (NCT00461630)
- Testing
- ER niacin/laropiprant, simvastatin, ezetimibe/simvastatin
- Where
- United Kingdom
- Volunteers
- 25,673 people
- Sponsor
- University of Oxford
Cerebrovascular Accident
Robotics For Rehabilitation Therapy: Functional Versus Individual Joint Training
The purpose of this study is to develop an upper extremity robotic training system for use by people with stroke to practice arm and hand movement in the clinic.
- Trial name
- NCT01050231
- Testing
- Functional/ Multi-joints activities, Individual Joint Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Stroke
Resistive Training Combined With Nutritional Therapy After Stroke
Stroke survivors experience severe muscle wasting during the chronic phase of recovery, with implications for strength, function and general health.
- Trial name
- REPS (NCT02347995)
- Testing
- Protein
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- VA Office of Research and Development
Chronic Stroke Survivors, Post-stroke Balance Impairment
Sprinter vs Skater Coordination Synergy Training for Balance and Coordination in Chronic Stroke
This study compares two types of coordinative locomotor training - the sprinter coordination synergy and the skater coordination synergy - to improve balance and coordination in people with chronic stroke (more than six months…
- Trial name
- SPRINT-SKATE (NCT07658495)
- Testing
- CLT - Sprinter Coordination Synergy, CLT - Skater Coordination Synergy
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Stroke, Acute Ischemic, Medium Vessel Occlusion
INTRA-ARTERIAL MeVO TREATMENT (IMP-ACT) Within the ACT-GLOBAL Adaptive Platform Trial-NCT06352632
This domain will be conducted as part of ACT-GLOBAL platform trial and will have the nested domain name of IMP-ACT. Acute ischemic stroke (AIS) caused by intracranial arterial occlusion remains a major cause of disability and…
- Trial name
- IMP-ACT (NCT07906275)
- Testing
- Mechanical Endovascular Thrombectomy, Intravenous Thrombolysis, Tenecteplase/Alteplase- depending upon availability at each treating centre
- Where
- 4 sites in Canada
- Volunteers
- 800 people
- Sponsor
- University of Calgary
Paroxysmal Atrial Fibrillation, Cryptogenic Stroke
Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke
Stroke recurrence largely depends on the detection of the cause and the control of vascular risk factors, with occult atrial fibrillation (AF) being one of the most important.
- Trial name
- SMARTTHUNDER (NCT05565781)
- Testing
- ECG smartwatch, Insertable Cardiac Monitor (ICM), External ECG Monitoring
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Cardiology, Stroke/TIA
Zio Real-World Evaluation
In 2020 an independent evaluation of the Zio service as part of the Digital Health Technologies programme at NICE was conducted.
- Trial name
- NCT05560828
- Testing
- Zio XT service
- Volunteers
- 1,440 people
- Sponsor
- King's College London
Ischemic Stroke, Intracranial Hemorrhages
Registry of Patients With Remote Posterior cErebral Hemorrhage Following Reperfusion Treatment in Ischemic Stroke
Introduction Remote cerebral hemorrhage following reperfusion treatment in ischemic stroke is rare (1.3-3.7% of all treated strokes) and is associated with worse functional and vital prognosis.
- Conditions
- Ischemic Stroke, Intracranial Hemorrhages, Hemorrhagic Transformation Stroke
- Trial name
- HEROES-CAT (NCT05871528)
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Heart Arrest, Out-Of-Hospital, Computed Tomography
Head Computed Tomography for Predicting Neurological Outcome After Cardiac Arrest
The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) joint guidelines for post-resuscitation care recommend a multimodal approach to prognostication of neurological outcome.
- Conditions
- Heart Arrest, Out-Of-Hospital, Computed Tomography, Unconsciousness, Neurologic Deficits
- Trial name
- NCT03913065
- Testing
- CT
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Lund University
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