Clinical trials: Study Protocol Feasibility
Mental Disorders
Reducing Stigma Among Healthcare Providers to Improve Mental Health Services
A growing number of trials have demonstrated treatment effectiveness for people with mental illness (PWMI) by non-specialist providers, such as primary care and community health workers, in low-resource settings.
- Trial name
- RESHAPE-mh (NCT02793271)
- Testing
- RESHAPE, PRIME/mhGAP
- Where
- Nepal
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brandon A Kohrt, MD, PhD
Physical Activity, Life Style
Cardiovascular Disease Prevention Strategies for High-risk Urban Sedentary Employees in Karachi, Pakistan
Heart diseases and other non-communicable diseases are serious health issues in countries like Pakistan. Many people who work in offices, like bank employees, sit for more than 8 hours a day.
- Conditions
- Physical Activity, Life Style, Dietary Habits, Cardiovascular Diseases
- Trial name
- m-LIfE (NCT06981247)
- Testing
- m-LIfE: mobile based lifestyle intervention for employees to increase their physical activity and promote healthy diet., Routine care arm
- Where
- Pakistan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Healthy Women
TMS-Induced LH Response in Healthy Women in Luteal Phase
The purpose of this research is to establish whether non-invasive Transcranial Magnetic Stimulation (TMS), can affect modulation of hormones such: Luteinizing Hormone (LH) and Follicle-stimulating hormone (FSH).
- Trial name
- NCT07363421
- Testing
- Transcranial Magnetic Stimulation Active
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Pregnancy, Prolonged, Induced; Birth
Membrane Sweeping to Prevent Post-term Pregnancy: The MILO Study
Multicentre, pragmatic, parallel group, pilot randomised controlled trial with an embedded factorial design.
- Conditions
- Pregnancy, Prolonged, Induced; Birth, Pregnancy Related
- Trial name
- MILO (NCT04307199)
- Testing
- Amniotic membrane sweep
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Reproducibility of Results
Reproducibility of Brain MRI
The aim of this study is to assess the reproducibility over time of functional and structural magnetic resonance imaging, as well as specific biomarkers in plasma in healthy volunteers before and after a two-hour rest.
- Trial name
- DANA0 (NCT03876236)
- Where
- 2 sites in Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Neurocognitive Decline, Feasibility
Comparison Between Analog Neurocognitive Tests Conducted by a Trained Test Leader Versus Self-administered Digital Tests
The study has a randomized crossover design including qualitative interviews of the participant's test experiences. Healthy participants, ≥60 years are eligible to participate in the study.
- Conditions
- Neurocognitive Decline, Feasibility, Costs, Interviews
- Trial name
- PICASU-Eq (NCT05253612)
- Testing
- Analog testing conducted by a trained test leader using, ISPOCD test battery, self-administered Mindmore digital cognitive screening battery
- Where
- Sweden
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Testing Protocol With Healthy Individuals for Feasibility
Parent-Adolescent Training on Neurofeedback and Synchrony
The study will test a real-time functional magnetic resonance imaging (fMRI) hyperscanning neurofeedback protocol for feasibility with ten mothers and their psychiatrically healthy adolescent daughters, with the eventual goal to…
- Trial name
- NCT03929263
- Testing
- Real-time fMRI neurofeedback
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Gastric Residual Volume
Feasibility of 1 Hour Clear Fluid Fasting Prior to Paediatric GA
The study is aim to investigate the appropriate fasting time for clear fluid in paediatric patients who plan for elective minor surgery.
- Trial name
- NCT03952260
- Testing
- Fasting time for clear fluid prior to anaesthesia
- Where
- Malaysia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ma Tai Jiun
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Resilience, Psychological, Older Adults (60 - 85 Years Old)
Resilience-Building Intervention for Older Informal Caregivers
The goal of this pilot study is to test whether a newly developed resilience-building program is feasible and acceptable for older adults who provide unpaid care to people with functional impairment in the community.
- Conditions
- Resilience, Psychological, Older Adults (60 - 85 Years Old), Community Dwelling, Informal Caregiver
- Trial name
- NCT07712744
- Testing
- Multicomponent Resilience-building Program, AI Chatbot and Telephone Follow-up Group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Intervention
Protocol: Feasibility of an Online Intervention to Increase Awareness of Gynaecological Cancer in UK Students
In the UK more than 2500 young people are diagnosed with cancer each year, including gynaecological cancers) and almost a third will be diagnosed within accident and emergency departments.
- Trial name
- GoCheck (NCT07147283)
- Testing
- Educational film and volitional help sheet
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Healthy Participants, Young Adults
VR for Hope: A Brief VR Self-help Protocol to Enhance Hope and Well-being in Young Adults
The objective of this study is to evaluate the feasibility of a brief self-help protocol based on immersive Virtual Reality (VR) to promote hope and psychological well-being in young adults while enhancing their mentalization…
- Trial name
- NCT07483762
- Testing
- VR for Hope intervention
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Sequence Optimization, Protocol Optimization
Optimization of Cardiac-MR Protocols
The aim of the present study is the optimization of various magnetic resonance (MR) investigation protocols of the heart and the lung without contrast agent application as well as the generation of normal values from cardiac MR…
- Conditions
- Sequence Optimization, Protocol Optimization, Normal Values, Feasibility
- Trial name
- NCT00557869
- Where
- Austria
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Pancreatic Cancer, Pancreatic Neoplasms
Pancreatic Cancer Screening Using the Enzeavour Assay in Japan
This nationwide, multicenter, prospective, single-arm interventional feasibility study evaluates the Enzeavour Pancreatic Cancer assay in routine health checkups and cancer screening in Japan.
- Trial name
- ENZEAVOUR FS (NCT07605819)
- Testing
- Enzeavour Pancreatic Cancer Assay
- Where
- 69 sites in Japan
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Cosomil, Inc.
Memory Dysfunction, Neurorehabilitation
A Virtually Delivered Memory Rehabilitation Protocol in Older Adults
The investigators conducted a feasibility study of a virtually-delivered adaptation of an ecologically oriented neurorehabilitation of memory (EON-Mem) in improving memory for healthy older adults.
- Trial name
- EONMem_OA (NCT06187857)
- Testing
- Ecologically Oriented Neurorehabilitation of Memory (EON-Mem)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Obesity, Childhood Obesity
Protocol Feasibility Study of HENRY
Tackling obesity is a public health priority. Childhood obesity is of particular concern due to its impact on physiological and psychological health and likelihood of tracking into adulthood, with associated diseases and…
- Trial name
- NCT03333733
- Testing
- HENRY
- Where
- United Kingdom
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Colon Cancer, Bowel Cancer
Clinical Study to Establish the Feasibility and Usability of the EndoRings™
The purpose of this prospective clinical study is to establish the feasibility and usability of the ENDORINGS™ when used during standard colonoscopy procedure.
- Conditions
- Colon Cancer, Bowel Cancer, Colorectal Cancer
- Trial name
- NCT01868971
- Testing
- EndoRings
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- EndoAid
Cancer
The ThinkCancer! Feasibility Study
Background Wales, like other UK countries, has relatively poor cancer outcomes. Late diagnosis and a slow referral process are major contributors.
- Trial name
- NCT04823559
- Testing
- ThinkCancer workshop
- Where
- 7 sites in United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bangor University
Colorectal Cancer, Surgery-Complications
Early Discharge After Robotic Colorectal Surgery (eRCS): a Prospective Observational Study
The enhanced recovery after surgery (ERAS) scheme has improved recovery of patients by addressing the surgical stress and enabling a proactive perioperative care which has proven to decrease postoperative complications and reduce…
- Trial name
- eRCS (NCT05408182)
- Testing
- Robotic colorectal resection with ERAS (or eRCS) perioperative care
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ospedale di Camposampiero