Clinical trials: Study Protocol Feasibility
Metastatic Cancer, Pain
Percutaneous Cryoablation in Treating Patients With Painful Bone Metastases
RATIONALE: Percutaneous cryoablation may help relieve pain caused by bone metastases. PURPOSE: This clinical trial is studying the side effects and how well percutaneous cryoablation works in treating patients with painful bone…
- Conditions
- Metastatic Cancer, Pain, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00608855
- Testing
- questionnaire administration, cryosurgery, pain therapy
- Where
- 10 sites in United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Polycystic Ovary Syndrome
Effect of Exercise on Cardiometabolic Profile in Women With Polycystic Ovary Syndrome
Polycystic Ovary Syndrome (PCOS) is a complex hormonal and metabolic disorder that has been shown to affect women's fertility. It can also share many symptoms with pre-diabetes, and women with PCOS often have an increased risk…
- Trial name
- NCT03678714
- Testing
- Exercise Intervention, Lifestyle Physical Activity
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Sheffield Hallam University
Gastric Residual Volume
Feasibility of 1 Hour Clear Fluid Fasting Prior to Paediatric GA
The study is aim to investigate the appropriate fasting time for clear fluid in paediatric patients who plan for elective minor surgery.
- Trial name
- NCT03952260
- Testing
- Fasting time for clear fluid prior to anaesthesia
- Where
- Malaysia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ma Tai Jiun
Heart Failure, Self-care
mHealth Intervention to Support Self-care During the Hospital to Home Transition in Individuals With Heart Failure
This study is a pilot randomized controlled trial designed to evaluate the feasibility, acceptability, usability, and preliminary efficacy of a mobile health (mHealth) educational self-management intervention for individuals with…
- Conditions
- Heart Failure, Self-care, Transitional Care
- Trial name
- HF-mHealth (NCT07478081)
- Testing
- mHealth Educational Self-Management Application, Usual transitional care
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Universidad de la Sabana
Autism Spectrum Disorder
Feasibility Testing and Pilot Study of V-MOTIVE Protocol Software Version 1
This is a project to be funded by a Fast-Track Small Business Innovative Research to build and test the feasibility of a new software prototype called V-Motive which will facilitate the combination of two proven autism behavioral…
- Trial name
- NCT02500771
- Testing
- ABA therapy enhanced with V-Motive software
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Experiad LLC
Diabetes Mellitus, Comorbidities and Coexisting Conditions
MDT Conferences for People With Diabetes and Multimorbidity
The goal of this observational study is to test if regular meetings (multidisciplinary team conferences) between several different medical doctors can work well in everyday hospital life.
- Trial name
- NOMAD (NCT05913726)
- Where
- Denmark
- Volunteers
- 55 people
- Sponsor
- Odense University Hospital
Frail Older Adults
Effect of Involving Community-dwelling Older Adults in Activities in Relation to Meals
Community-dwelling older adults receiving support at home such as meals-on-wheels may lose the ability to preserve social, cognitive, and functional abilities, when becoming accustomed to and dependent of community aged care.
- Trial name
- NCT03289598
- Testing
- A rehabilitation process involving collaborative goal setting with a case manager about managing own food and meals
- Where
- Denmark
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- The Danish Dietetic Association
Depressive Disorder, Major
Dexmedetomidine Adjuvant Treatment for Depressed Patients Undergoing ECT
Major depressive disorder (MDD) is a highly prevalent and disabling condition for which the currently available treatments are not fully effective.
- Trial name
- NCT04661475
- Testing
- Dexmedetomidine Injection [Precedex], Normal saline
- Volunteers
- 76 people
- Sponsor
- Sultan Qaboos University
Anterior Cruciate Ligament Rupture, Enhanced Recovery After Surgery (ERAS) Protocol
Effectiveness of Enhanced Recovery After Surgery (ERAS) Protocols for Arthroscopic Anterior Cruciate Ligament Reconstruction in an Ambulatory Surgery Setting
The anterior cruciate ligament (ACL) is a critical component for maintaining knee stability by resisting anterior tibial translation and internal rotation.
- Conditions
- Anterior Cruciate Ligament Rupture, Enhanced Recovery After Surgery (ERAS) Protocol, Ambulatory Surgery
- Trial name
- NCT07602231
- Testing
- Enhanced Recovery After Surgery
- Volunteers
- 115 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Parkinson Disease
Feasibility of a Behavioural Activation Protocol to Support People With Parkinson's Enhanced by VR
The proposed research project will involve developing and testing the feasibility of a 6 week Behavioural Activation (BA) programme for people with Parkinson's Disease, which will be enhanced by Virtual Reality exercise…
- Trial name
- BAPP-VR (NCT07038603)
- Testing
- BAPP-VR
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Waitlist Control, Intervention (Training) Condition
Feasibility and Outcomes of Therapist-led Online Cancer Bereavement Groups
Background: The loss of loved one to cancer brings unique difficulties that impact on the bereavement experience. Mixed support exists for the effectiveness of in-person group interventions for bereaved caregivers, with barriers…
- Trial name
- NCT07002424
- Testing
- Therapeutic - Psychological
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Newborn Complication, Premature
Between Urgency and Efficiency: Assessing the Feasibility of Implementing a Protocol for the Care of Extremely Premature and Very Low Birth Weight Infants During the First Hour of Life: GOLD Study
Premature newborns are a particularly vulnerable population, especially during the first hours of life as they adapt to life outside the womb.
- Trial name
- GOLD (NCT07461623)
- Testing
- Golden Hour protocol
- Sponsor
- Centre Hospitalier Universitaire de Nice
Physical Inactivity, Frailty
The 'Outdoor Rehab-Fit' App-based Physical Activity Education Intervention for Frail Older Adults in Hong Kong
In recent years, research teams around the world have developed interventions to educate older adults to use outdoor exercise facilities (OEFs) to improve health outcomes like strength, balance, mobility, PA level, and weight.
- Trial name
- NCT06326710
- Testing
- mHealth, Health Talk
- Where
- Hong Kong
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
End Stage Renal Failure
Volume,Sodium and Blood Pressure Management in HD
The purpose of this study to conduct a pilot, randomized trial in stable HD patients to evaluate the effect of gradual, step-wise reduction of post-hemodialysis target weight, combined with diligent dietary sodium restriction and…
- Trial name
- VSBP (NCT01766882)
- Testing
- Lower sodium intervention, Progressive Challenge to Post Dialysis Weight
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Study Protocol Feasibility, Non Clinical Anxiety
Effects of Darkness Retreat: a Pilot Study
The primary goal of this pilot study is to test the feasibility and safety of a research protocol for a voluntary darkness retreat.
- Conditions
- Study Protocol Feasibility, Non Clinical Anxiety, Non Clinical Worry, Non Clinical Rumination
- Trial name
- NCT07429617
- Testing
- Darkness Retreat - Several Days of Seclusion in Complete Darkness
- Where
- 2 sites in Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
PTSD (Childbirth-Related), Psychological Wellbeing
Feasibility and Efficacy of GTEP for Birth Trauma
This clinical study aims to evaluate the feasibility and initial efficacy of Group Traumatic Episode Protocol (GTEP) for reducing trauma symptoms (measured by the PCL-5 and City BiTS) for individuals following a traumatic…
- Conditions
- PTSD (Childbirth-Related), Psychological Wellbeing, Bonding
- Trial name
- NCT07246356
- Testing
- Group Traumatic Episode Protocol (GTEP)
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University of Birmingham
Intracranial Aneurysms
Canadian eCLIPs™ Safety and Feasibility Study Protocol
The purpose of this study is to evaluate the safety and feasibility of the eCLIPs™ Family of Products for the treatment of unruptured intracranial bifurcation aneurysms in conjunction with embolization coils.
- Trial name
- CESIS (NCT01957683)
- Testing
- eCLIPs™ Family of Products
- Where
- 5 sites in Canada
- Sponsor
- Evasc Medical Systems Corp.
Obesity
Progressive Resistance Training in Patients With Class III Obesity
To test the strength and physical performance outcomes of a 12-week progressive resistance training (PRT) exercise program in a small cohort of patients with Class III obesity who are preparing for bariatric weight loss surgery…
- Trial name
- NCT01100450
- Testing
- Progressive Resistance Training
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Beth Israel Deaconess Medical Center
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dementia
A Trial of a Multi-component Individualized Telephone-based Support Intervention for Adult-child Caregivers Caring for Parents With Dementia
This is the first randomized controlled trial exploring the implementation of a multi-component individualized telephone-based support intervention for adult-child caregivers caring for parents with dementia in China.
- Trial name
- NCT03378050
- Testing
- HEART, Usual Care
- Sponsor
- Yale University