Clinical trials: Subarachnoid Block
Postoperative Pain
Adding Different Additives to Bupivacaine-fentanyl Mixture in Spinal Anesthesia for Cesarean Section
Spinal anesthesia is widely used in cesarean section, but it is associated with high incidence of side effects. To reduce the occurrence of side effects, intrathecal adjuvant was recommended to use in spinal anesthesia, with the…
- Trial name
- NCT04464616
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Caesarean Section
Optimization of Hemodynamic Conditions During Caesarean Section Under Spinal Anaesthesia
The purpose of this study is to determine wether intravenous Phenylephrine, administered as start bolus and following continuous infusion (specific dosage per weight), or optimal lower limb bandaging is more effective in…
- Trial name
- NCT01278238
- Testing
- Phenylephrine, Lower limb compression
- Where
- Norway
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Anestesiavdelingen Baerum Sykehus
Hypotension, Anesthesia
Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System
Maternal hypotension during spinal anaesthesia for Caesarean delivery may bring various adverse effects. It is therefore important to closely monitor hypotension during spinal anaesthesia, however current technology does not…
- Trial name
- ADIVA (NCT03620942)
- Testing
- Phenylephrine, Ephedrine, ADIVA System
- Where
- Singapore
- Volunteers
- 173 people
- Sponsor
- KK Women's and Children's Hospital
Hypotension, Controlled, Anaesthesia, Spinal
Non Invasive Haemodynamics in Neuraxial Anaesthesia Hypotension
Spinal (or neuraxial) anaesthesia is still considered the first choice technique for elective Caesarean section as simple, quick, reliable and cheap.
- Conditions
- Hypotension, Controlled, Anaesthesia, Spinal, Caesarean Section
- Trial name
- NIHNAH (NCT03653442)
- Where
- Italy
- Volunteers
- 55 people
- Sponsor
- Papa Giovanni XXIII Hospital
Complications; Cesarean Section
Spinal Aesthesia in Women With Placenta Previa Percreta
Placenta previa percreta is a dangerous complication during surgery. Due to the high risk of hemorrhage, most parturients with placenta previa have to accept cesarean section.
- Trial name
- SAW (NCT02686242)
- Testing
- spinal anesthesia, general anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Air Force Military Medical University, China
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Adequate Anesthesia With Unimpaired Motor Strength
Comparison of Intrathecal Fentanyl or Sufentanil in 1 mg Bupivacaine Spinal Anesthesia for TURP in Elderly Patients
Adequate sensory block for surgical procedure without side effects and immediate mobilization after surgery are desirable anesthetic technique in various surgeries.
- Trial name
- NCT01608334
- Testing
- Fentanyl, Sufentanil
- Where
- South Korea
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Varicocele
Effect of TAP Block for Postoperative Pain Control After Varicocele Operations.
TAP block is the administration of local anesthetic agents into the anatomic neurofascial cavity between the internal oblique and transversus abdominis muscle in the antero-lateral region of the abdomen to block the anterior…
- Trial name
- NCT02983383
- Testing
- TAP block group (Group T), spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Bladder Cancer
Comparison of Nerve Stimulating Approach and Interfascial Injection Approach During Sono-guided Obturator Nerve Block
Transurethral resection of bladder tumor (TURB) has been essential treatment for bladder tumours. Direct electrical stimulation of an obturator nerve during the TURB procedures can trigger an inadvertent adductor muscle spasm…
- Trial name
- NCT02452944
- Testing
- nerve stimulator (stimuplex HNS12), ultrasound
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Gachon University Gil Medical Center
Spinal Anaesthesia
Effect of Diabetes Mellitus on Spinal Block Criteria During Cesarean Section
The current study aimed at studying the effect of DM during pregnancy on the spinal block criteria during C.S. The primary end point of the trial is the incidence of complete failure of spinal block.
- Trial name
- NCT03440502
- Testing
- spinal anaesthesia
- Volunteers
- 300 people
- Sponsor
- Assiut University
Fracture Pelvis
Comparison Between Dexamethasone and Dexmedetomidine in Spinal Anesthesia for Cases With Fracture Pelvis Fixation
The aim of this study is to compare dexamethasone and dexmedetomidine as adjuvant to bupivacaine in fracture pelvis fixation as regard duration of sensory block and postoperative pain management.
- Trial name
- NCT07485127
- Testing
- 60 patients will be involved, half patients will receive 13mg bupivacaine + 4 mg dexamethasone. The other half will receive 13mg bupivacaine + 4 mg dexmedetomidine. All will be monitored closely.
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Combined Spinal Epidurai Anesthesia, Lower Extremity Surgery
the Relationship Between Vertebral Body Length, Subarachnoid Space Width and Block Level
Spinal anesthesia technology has been widely used in various surgeries and multi-mode analgesia. Spinal ultrasound imaging has been proved to be a reliable tool for evaluating spinal parameters.
- Trial name
- NCT05201261
- Testing
- ltrasonic measure
- Volunteers
- 50 people
- Sponsor
- Shengjing Hospital
Transurethral Prostatectomy
The Effects of Intravenous Dexmedetomidine on Spinal Anesthesia Using Low Dose Diluted Bupivacaine for Transurethral Resection of Prostate
Dexmedetomidine is a new selective and potent alpha-2 agonist. It has centrally acting anesthetic properties. It has been known that intrathecal addition of alpha-2 adrenergic agents result in prolongation of the duration of the…
- Trial name
- NCT01224470
- Testing
- Dexmedetomidine
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- Yonsei University
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Diuresis, Bladder Retention Volume
Effect of Preload on Bladder Retention Volume During Spinal Anesthesia
The purpose of this study is to assess the influence of different fluid infusions on the quantity of bladder retention after spinal anesthesia.
- Conditions
- Diuresis, Bladder Retention Volume, Hypotension
- Trial name
- NCT00550186
- Testing
- Ringers Lactate, HaemoHES 6%
- Where
- Netherlands
- Volunteers
- 144 people
- Sponsor
- Rijnstate Hospital
Postoperative Pain
Comparison of Pain Relief Duration With Dexmedetomidine Versus Fentanyl Added to Spinal Anesthesia in Patients Undergoing Lower Limb Orthopedic Surgery
The goal of this randomized clinical trial is to compare how long effective pain relief lasts when dexmedetomidine or fentanyl is added to hyperbaric bupivacaine during spinal anesthesia for lower limb orthopedic surgery.
- Trial name
- NCT07770542
- Testing
- Dexmedetomidine & Bupivacaine., fentanyl and bupivacaine
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Allama Iqbal Teaching Hospital
Orthopedic Disorder
The Duration of Spinal Anaesthesia - a Prospective, Observational Cohort Study
Today, surgery in an ambulatory setting is preferred for many reasons. Total hip and knee arthroplasty (THA and TKA) are now procedures where patients can be sent home on the same day of the surgical procedure.
- Trial name
- Spinalrocks (NCT06459986)
- Where
- 2 sites in Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Cesarean Section Complications, Hypotension
Can Right Toe Perfusion Index or Pleth Variability Index Predict Spinal Anesthesia Induced Hypotension?
Spinal anesthesia for caesarean section is associated with a decrease in systemic vascular resistance and cardiac output and may cause hypotension in a significant portion of the parturients.
- Conditions
- Cesarean Section Complications, Hypotension, Spinal Anesthesia, Perfusion Index
- Trial name
- NCT03956186
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Cesarean Delivery Affecting Newborn, Acidosis
Ephedrine Versus Norepinephrine and Fetal Acid-Base Status During Cesarean Delivery Under Spinal Anesthesia
This study compares ephedrine and norepinephrine for the treatment of low blood pressure (hypotension) that may occur during cesarean delivery under spinal anesthesia.
- Conditions
- Cesarean Delivery Affecting Newborn, Acidosis, Maternal Hypotension, Spinal Aneshtesia
- Trial name
- NEO-FET (NCT06921473)
- Testing
- Norepinephrine, Ephedrine
- Where
- Turkey (Türkiye)
- Volunteers
- 155 people
- Sponsor
- mehmet özkılıç
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