Clinical trials: Substance Related Problem
Adolescent Drinking, Adolescent Problem Behavior
Mindfulness Mobile App to Reduce Adolescent Substance Use
Substance-abusing youth - especially those who are involved in the juvenile justice system - are at higher risk than nonusers for mental health problems, including depression, conduct problems, personality disorders, suicidal…
- Trial name
- Qlarity (NCT04027075)
- Testing
- Qlarity app users
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Alcohol-Related Disorders, Alcohol Use Disorders
Adaptive Interventions for Problem Drinkers
The purpose of this study is to understand how certain interventions help people reduce or quit their drinking and how certain interventions may help best at certain points in time in the change process.
- Conditions
- Alcohol-Related Disorders, Alcohol Use Disorders, Alcohol Drinking, Alcoholism
- Trial name
- NCT02511808
- Testing
- Brief Advice, Motivational Interviewing, Behavioral Self-Control Training
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Northwell Health
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Psycho-social Support on Mental Health and Hope of Adolescents Affected by Earthquake in Nepal
Adolescents are prone to mental health problems such as post-traumatic stress disorder (PTSD) and depression which could become worse in the aftermath of disasters.
- Trial name
- NCT03387007
- Testing
- Psychosocial support training for school teachers
- Volunteers
- 1,912 people, healthy volunteers welcome
- Sponsor
- Tokyo University
Substance Use Disorders
Interventions for HIV+ Mothers With Problem Drinking
The purpose of this study is to evaluate the efficacy of a 14-session behavioral intervention for HIV-infected and uninfected mothers with problem drinking.
- Trial name
- NCT00183209
- Testing
- Family First
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- New York University
Problem Drinking
An Evaluation of the Brief Interventional for Problem Drinkers Among Medical Inpatients
Compared with control participants at post-intervention follow-ups, unhealthy drinkers who receive the screening and brief intervention will (1) report reduced alcohol consumption among all patients, and (2) report reduced…
- Trial name
- BI (NCT00675519)
- Testing
- Motivational enhancement therapy
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Mackay Memorial Hospital
Pregnancy Related, Substance Use
NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health
This exploratory study brings together an interprofessional team, novel tools, and innovative, community-driven care delivery approaches to improve health equity among mother-infant dyads impacted by substance use disorder and…
- Conditions
- Pregnancy Related, Substance Use, Mental Health Issue
- Trial name
- NEXUS (NCT05814575)
- Testing
- NEXUS intervention, Standardized Non-Medical fetal ultrasound
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
HIV/AIDS, Young Adult
Intervention for Virologic Suppression in Youth
The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old).
- Conditions
- HIV/AIDS, Young Adult, Mobile Health, Mental Health Issue
- Trial name
- iVY (NCT05877729)
- Testing
- Standard of Care, Video-counseling+app
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Suicide, Attempted, Drug Use
Brief New Treatment for Suicide Attempts
Individuals with alcohol or drug use problems who are hospitalized for suicide attempt are at high risk for reattempt. This treatment development study adapts a promising outpatient intervention to prevent suicide reattempt in…
- Conditions
- Suicide, Attempted, Drug Use, Alcohol; Use, Problem
- Trial name
- NCT03300596
- Testing
- Brief intervention to prevent suicide attempt, Enhanced treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Alcohol-Related Disorders, Alcohol Drinking
Stepped Interventions for Problem Drinkers
In a randomized controlled trial, patients recruited in general practices and fulfilling criteria for alcohol dependence, alcohol abuse, at-risk drinking or binge drinking will be allocated to three conditions: (1) Stepped Care…
- Trial name
- NCT00391742
- Testing
- Brief intervention
- Volunteers
- 450 people
- Sponsor
- University of Luebeck
Alcohol Abuse, Post-Traumatic Stress Disorder
Pilot Evaluation of the VetChange Mobile App for Veterans With PTSD Who Engage in Problem Drinking
Concept: Alcohol misuse is common among Veterans with PTSD. It has been proposed that this high comorbidity is the result of "self-medication," with alcohol being used to alleviate common PTSD symptoms (e.g., hyperarousal, sleep…
- Trial name
- NCT03208738
- Testing
- VetChange, web-based drinking assessment and feedback tool (AFT)
- Volunteers
- 280 people
- Sponsor
- Eric Kuhn
Substance Abuse, Sleep Disturbances
Exploring Substance Use, Sleep Disturbances and Reward Sensitivity
According to foreign medical studies, substance use is closely related to reward sensitivity and sleep patterns. The purpose of this research is to understand the relationship between these three factors, which will help improve…
- Trial name
- NCT07028346
- Testing
- Cognitive Behavioral Therapy for Insomnia, Sleep Education
- Volunteers
- 154 people
- Sponsor
- Kwai Chung Hospital
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Adolescent Problem Behavior, Truancy; Unsocialized
Substance Use Interventions for Truant Adolescents
This study evaluates a brief motivation-building intervention for parents and teens to reduce truancy and substance use. It is hypothesized that the motivational intervention will result in better outcomes compared to an…
- Conditions
- Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized
- Trial name
- GOALS (NCT03655574)
- Testing
- Motivational + Family Check-up (MET+FCU), Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Brown University
Prostate Cancer, Urologic Cancer
The Man Van Project
National Health Service (NHS) England has commissioned The Royal Marsden Hospital NHS Foundation Trust to run a novel mobile clinical outreach service called 'Man Van' with the aim of enabling male patients' easy access to care…
- Conditions
- Prostate Cancer, Urologic Cancer, Urologic Diseases, Bladder Cancer
- Trial name
- MV (NCT06357416)
- Testing
- MV-POCT Sub-study, Main Man Van Group Sub-study (MV-Eco), MV-QualQ Sub-study
- Where
- United Kingdom
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Substance Use, Stress
Automating Peer Learning to Reduce Alcohol Use and Related Deviant Behavior in Secondary School
Deviant peer affiliation is one of the most important predictors of alcohol use in adolescence. These affiliations arise when socially marginalized youth self-aggregate and reinforce alcohol use and other deviant activity (i.e.…
- Conditions
- Substance Use, Stress, Relation, Interpersonal, Bullying
- Trial name
- PeerLearning (NCT04478240)
- Testing
- PeerLearning.net
- Where
- United States
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia
INCLUDE: Using Lived Experience to Improve Mental Health Diagnosis v1
The focus of this study is not about what it is like to have a mental disorder, but instead the diagnostic experience. Some people find diagnoses helpful, but some find them upsetting and harmful.
- Conditions
- Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Schizophrenia, Generalised Anxiety Disorder, Bipolar Disorder
- Trial name
- INCLUDE (NCT03131505)
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- Norfolk and Suffolk NHS Foundation Trust
Alcohol Use Disorder
Exploring Regulation and Function of Dopamine D3 Receptors in Alcohol Use Disorders: A [11C]-(+)-PHNO Study
There is a need to better understand the mechanisms underlying alcohol use and dependence in order to advance the clinical treatment of alcohol dependence.
- Trial name
- NCT03037060
- Testing
- [11C]-(+)-PHNO PET scan, Alcohol Self-Administration, Craving Task
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Centre for Addiction and Mental Health
Substance Use, Mental Health Issue
Adolescent Screening and Personalized Intervention Resource for Enhancement of Behavioral Health and Substance Use
Only a small fraction of youth who are beginning to experience behavioral health problems and use alcohol or illicit drugs receive needed treatment services due to the lack of accessible, effective early intervention resources.
- Trial name
- ASPIRE (NCT06306287)
- Testing
- ePACE Personalized Intervention, eFACE Fixed Intervention
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Oregon Research Institute
Umbilical Cord Issue, Nicotine Addiction
Nicotine's Effect on Cancer Stem Cell Markers in Human Umbilical Cord Tissue
The umbilical cord is generally an organ that clinicians and pathologists do not pay sufficient attention to. The absence of significant pathology in the umbilical cords, along with the lack of association between certain…
- Conditions
- Umbilical Cord Issue, Nicotine Addiction, Pregnancy Related, Cancer
- Trial name
- NCT06678152
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Alcohol Dependence, Alcohol Abuse
Project Motion, A Study of Motivational Interviewing to Reduce Heavy or Problematic Drinking
The purpose of this pilot study is to investigate the critical components of motivational interviewing (MI), a psychotherapeutic intervention, in reducing heavy or problematic drinking.
- Trial name
- NCT00665249
- Testing
- Motivational Interviewing, Spirit-Only Motivational Interviewing, Self-Change
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Northwell Health