Clinical trials: Substrate Oxidation
Obesity
Differences in Nutrient Use During Exercise Between Children of Varying Body Mass Indices and Fitness Levels
Children who have previously participated in the study "MI Energy" will be invited to participate in "SUPER kids". Investigators want to better understand differences in nutrient use (e.g., fatty acid and carbohydrate) during…
- Trial name
- SUPERkids (NCT04819308)
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Diabetes Prevention, Obesity Prevention
PERFECT Project - Part 2 - Study 2
The objectives are to test the acute effects of different cereals containing pulse ingredients on: 1) aerobic endurance and substrate oxidation during exercise 2) response of blood glucose, insulin and appetite to an aerobic…
- Trial name
- NCT02370927
- Testing
- Control, Pea protein, Pea Starch
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hydration Status, Substrate Metabolism During Exercise
The Effect of Hydration Status on Substrate Oxidation at Rest and During Light and Moderate Exercise
Metabolic flexibility is the ability to properly switch between fat and carbohydrate stores to use for energy under different conditions (rest, feeding, exercise).
- Trial name
- NCT07298863
- Testing
- Part 1 - Exercise Trial, Part 1 - Experimental Trial, Part 2 - Oral Glucose Tolerance Test
- Where
- 2 sites in United States, Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Obesity
Sleep Restriction and Energy Expenditure
Each 4-day period will follow the same protocol. Basically, for the entire study, we will prepare all of the subject's food and will require him or her to eat all of the food that we give at the times we tell them to eat.
- Trial name
- NCT01751581
- Testing
- Short Sleep, Habitual sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Menopause
Eating Chocolate at the Right Time Benefits the Circadiam Sytem and Metabolic Efficiency.
The purpose of this investigation is to test the hypothesis that in humans, eating a relatively big amount of chocolate at the wrong time (bedtime) may disrupt our circadian system (change the circadian phase), while taking this…
- Trial name
- ONTIME-CHOC (NCT03949803)
- Testing
- Chocolate 100gr
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Obesity
The Acute Effect of Grains of Paradise (Aframomum Melegueta) on REE
Grains of paradise (Aframomumu melegueta) (GP), also known as Guinea pepper or Alligator pepper, belongs to the Zingiberaceae family, which is native to West Africa.
- Trial name
- NCT03894137
- Testing
- Grains of Paradise (Aframomum Melegueta)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Plexus Worldwide
Insulin Sensitivity/Resistance
Protective Effect of Exercise on Acute High-fat Overfeeding
Metabolic flexibility is the ability to switch rapidly from one substrate (i.e. fuel source) to another (e.g. fats to carbohydrates) in response to ingested foods.
- Trial name
- HFDEXC (NCT07633704)
- Testing
- High Fat Overfeeding, High Fat Overfeeding + Exercise
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- George Washington University
Substrate Absorption, Substrate Oxidation
Effect of Lactose, Fructose, Sucrose, Whey Protein, and Soy Protein on Substrate Absorption and Oxidation: a Pilot Study
Does the consumption of various combinations of mono and disaccharides (lactose, sucrose and fructose) and protein isolates (whey or soy) result in altered substrate absorption, substrate oxidation, and glucose regulation? This…
- Conditions
- Substrate Absorption, Substrate Oxidation, Glucose Regulation
- Trial name
- NCT00942513
- Testing
- trt 1, trt 2, trt 3
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- United States Department of Agriculture (USDA)
Menstrual Cycle, Substrate Metabolism
Effects of Resistance Training on Substrate Metabolism During the Menstrual Cycle
This research project's objective is to investigate substrate metabolism behavior in response to the RT during different phases of the menstrual cycle.
- Trial name
- NCT04024826
- Testing
- EFP, LFP, ELP
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Southern Illinois University Edwardsville
Dietary Manipulation
Dietary Macronutrient Manipulation and Substrate Oxidation During Exercise
This study will investigate the effect of dietary macronutrient manipulation on glycogen (stored carbohydrate) levels in the muscle and substrate oxidation during exercise.
- Trial name
- NCT02605291
- Testing
- Diet with a different macronutrient content A, Diet with a different macronutrient content B, Diet with a different macronutrient content C
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Metabolism
Development of Novel Therapies for NIDDM
The overarching goal of this program project grant is the development of technologies that lead to new methods for studying, detecting, and treating type 2 diabetes, and their integration with hypothesis-driven diabetes research…
- Trial name
- NCT01905722
- Testing
- 3 Tesla, 7 Tesla
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Duke University
Food Intake Regulation, Substrate Oxidation
Substrate Oxidation Does Not Affect Short Term Food Intake in Healthy Boys and Men
The purpose of this study is to investigate the effect of substrate oxidation, expressed by RER, on food intake regulation and net energy balance.
- Trial name
- NCT01888991
- Testing
- Glucose Preload and Exercise Intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Substrate Oxidation, Energy Expenditure
Exercise-Induced Rates of Fat Oxidation with and Without Ingestion of a Caffeine-Based Energy Drink
The purpose of this study is to evaluate acute changes in rates of fat oxidation during exercise with and without the ingestion of a caffeine-based energy drink.
- Conditions
- Substrate Oxidation, Energy Expenditure, Reaction Time, Cognition
- Trial name
- EDX (NCT06308731)
- Testing
- Caffeine-Based Energy Drink
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Glucose Levels, Lipid Profile
Effects of Fasted- Versus Fed-exercise on Metabolic Health in Physically Active Adults
The purpose of this study is to investigate whether the sequence meal and exercise (exercise before meal or exercise after meal) affects the postprandial metabolism.
- Conditions
- Glucose Levels, Lipid Profile, Substrate Oxidation, Blood Pressure
- Trial name
- NCT06949709
- Testing
- Fasted-exercise, Fed-exercise
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Taiwan Normal University
Postprandial Effect of Carbohydrate Beverage Consumption
Fat Burning After a Meal
The purpose of the study is to determine how adding a carbohydrate beverage to a meal with different protein levels affects the rate at which one's body burns fats, sugars, and proteins.
- Trial name
- NCT02211599
- Testing
- 15% protein, 30% protein, Sweetened beverage
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Overweight
Impact of Eating Beans on Metabolism
The purpose of this research is to test how eating a meal containing beans impacts how participants' bodies use food for energy.
- Trial name
- NCT06123208
- Testing
- Whole cooked pinto bean, Pinto bean flour, Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Healthy Adults
FueL Use During eXercise in Males and Females
This study will investigate whether pre-exercise nutrition influences sex differences in fuel utilization during endurance exercise.
- Trial name
- FLUX (NCT07829237)
- Testing
- Pre-exercise carbohydrate beverage, Pre-exercise protein beverage, Fasted control beverage
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Overweight and Obesity
Biking vs. Running: Comparison of EPOC, Substrate Oxidation, Appetite and Energy Intakes in Men With Overweight/Obesity.
The management of obesity involves hygienic and dietary measures that include appropriate nutrition and an increase in physical activity (PA).
- Trial name
- BIKERUN (NCT06082310)
- Testing
- Exercise
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Postprandial Metabolism, Healthy Volunteers
Postprandial Metabolic Responses to Sustainable and Non-Sustainable Meals in Healthy Young Men
This randomized crossover study evaluated the acute postprandial metabolic and hydration responses to two standardized lunch meals differing in nutritional quality and environmental footprint in healthy young men.
- Trial name
- THERMOS-LUNCH (NCT07808736)
- Testing
- Healthy-Sustainable Test Meal, Non-Sustainable Test Meal
- Where
- Italy
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Parma
Maximal Rate of Fat Oxidation
Dietary Correlates of the Maximal Capacity for Fat Oxidation
There is a large variability in people's ability to burn fat during exercise. It is thought that differences in dietary intake can partly explain this variation, however this has not been comprehensively studied.
- Trial name
- NCT02070055
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Birmingham