Clinical trials: Suicidal Ideation and Behaviors
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Anxiety
Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled Trial.
Experiences of violence, from micro to physical aggressions, have a deleterious impact on mental health. According to the Minority Stress Theory, unfavorable social conditions (such as anticipated and experienced discrimination…
- Conditions
- Depression, Anxiety, Psychological Distress, Social Phobia
- Trial name
- ESCREVA-SE (NCT05349877)
- Testing
- Expressive writing, Self-affirmation
- Where
- Brazil
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Suicide
Tool for Sibling and Children of Someone With Suicidal Thoughts
This study aims to investigate to what extent a website developed for siblings and children (16-25 years old) of someone with suicidal thoughts and/or behaviors is effective in improving perceived pressure, knowledge, attitudes…
- Trial name
- NCT06100575
- Testing
- Website (www.mee-leven.be)
- Where
- Belgium
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicidal Ideation, Suicide, Attempted
A Conditioning Paradigm to Increase Affinity for Sacredness of Life
Suicide-related experiences affect millions of people every year in the United States. Through decades of research, interventions targeting these experiences have developed with varied empirical support.
- Conditions
- Suicidal Ideation, Suicide, Attempted, Suicide and Self-harm, Non-suicidal Self-injury
- Trial name
- NCT05541900
- Testing
- TEC-Sacredness, TEC-Control
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Florida State University
Suicide, Attempted, Suicidal Ideation
A Study to Evaluate the Safety and Effectiveness of a Digital Therapeutic
The primary objective of this study is to assess the effectiveness of a digital intervention in reducing suicide attempts.
- Trial name
- NCT05144685
- Testing
- OTX-202, OTX-000, Treatment as Usual
- Where
- 6 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- Oui Therapeutics, Inc.
Depression, Suicidality
Development and Preliminary Trial of a Brief, Portable Health Intervention for Rural Sexual Minority Emerging Adults
The purpose of this study is to test the feasibility of writing interventions specifically designed for lesbian, gay, and bisexual (LGB) emerging adults (ages 18-29) that are aimed at improving the outcomes: depression…
- Conditions
- Depression, Suicidality, Substance Abuse, HIV
- Trial name
- Project LEAP (NCT03751020)
- Testing
- Expressive Writing (EW) Intervention, Self-Affirmation (SA) Intervention, Control
- Where
- 3 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Yale University
Rehumanization Intervention, Control Intervention
Reducing Self-Dehumanization to Examine Oxytocin and Suicide Risk
The goal of this experiment is to further determine if self-dehumanization is a novel risk factor for suicide. This study will reduce self-dehumanization using a novel re-humanization condition and compare this group to a control…
- Trial name
- NCT06713473
- Testing
- Rehumanized Intervention, Control Intervention, Clinical Interview
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Florida State University
Suicide Attempt, Depression
Effects of a Multifaceted School-Based Intervention to Protect Mental Health and Prevent Suicidal Behaviour in Adolescents in Spain
What is this study about? This study aims to find out if a school-based program can help improve mental health and prevent suicidal thoughts and behaviors in teenagers in Spain.
- Conditions
- Suicide Attempt, Depression, Adolescent Mental Health, Self-Harm
- Trial name
- NCT06996054
- Testing
- Multifaceted School-Based Mental Health and Suicide Prevention Program
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Fundació d'investigació Sanitària de les Illes Balears
Suicidal Ideas, Suicidal Ideation
Couple-Based Crisis Safety Planning
Suicide is a leading cause of death in Veterans. Suicide rates among Veterans have increased approximately 36% from 2001 to 2020.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Crisis; Emotional, Suicide Attempts
- Trial name
- CRP-C (NCT07012824)
- Testing
- Crisis Response Planning, Couples-based Crisis Response Planning
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Domestic Violence, Post-Traumatic Stress Disorder
Mental Health Symptoms and Intimate Partner Violence
Using a touch screen computer, the researchers are screening emergency department patients for intimate partner violence and mental health issues.
- Conditions
- Domestic Violence, Post-Traumatic Stress Disorder, Depression
- Trial name
- NCT00166075
- Testing
- Computer screen with community resource printout
- Where
- United States
- Volunteers
- 569 people, healthy volunteers welcome
- Sponsor
- Emory University
Major Depressive Disorder
miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome
The purpose of this study is to examine whether neural-derived exosomal miRNAs are differentially expressed that are specific to suicidal ideation or behavior, and which by affecting specific miRNA targets and pathways, are…
- Trial name
- NCT02418195
- Testing
- ketamine
- Where
- United States
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicidal Ideation
Evaluation of Creative Materials Supporting Healthcare Professionals in Discussing Suicidality in Children and Adolescents
Preliminary research clearly indicates a significant shortage of evidence-based tools and interventions specifically targeting suicidality among children and adolescents.
- Trial name
- NCT07043231
- Testing
- Creative materials
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Depression, Major Depressive Disorder
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional…
- Conditions
- Depression, Major Depressive Disorder, Suicidal Ideation
- Trial name
- NCT05977439
- Testing
- Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Covid19, Mental Health Disorder
MIND/COVID-19: Mental Health Impact and NeeDs Associated With COVID-19: a Comprehensive National Evaluation in Spain
The aim of the proposed project is to provide a comprehensive assessment of the mental health impact of the ongoing COVID-19 outbreak in Spain.
- Conditions
- Covid19, Mental Health Disorder, Mental Health Conditions
- Trial name
- NCT04556565
- Where
- 18 sites in Spain
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Jordi Alonso
Suicide, Suicidal Ideation
Piloting a Culturally Adapted Suicide Prevention for Black Students in Chicago
Suicide has been the third leading cause of death for Black youth in the U.S since the 1980s and persists as a leading cause of death for Black youth today.
- Conditions
- Suicide, Suicidal Ideation, Suicide Attempt
- Trial name
- SP-BSC (NCT07125144)
- Testing
- Black Youth Suicide Prevention in Chicago, Signs of Suicide: Standard/Existing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Suicide Attempts, Suicidal Ideation
Advancing Suicide Intervention Strategies for Teens During High Risk Periods
To inform the effective management of adolescent suicide risk by evaluating promising treatments and developing the evidence-base for interventions that are well suited for widespread adoption, sustained quality, and impact.
- Conditions
- Suicide Attempts, Suicidal Ideation, Suicide and Self-harm, Suicide Threat
- Trial name
- ASSIST (NCT05078970)
- Testing
- Safety Planning Intervention+ (SPI+), Collaborative Assessment and Management of Suicidality (CAMS), Treatment As Usual
- Where
- 2 sites in United States
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Self Harm, Depression
Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth
This study is designed to refine and test the efficacy of a computer assisted culturally informed and flexible/adaptive intervention for Latino adolescents for whom self-harm behaviors are a health disparity-specifically, Latinas…
- Conditions
- Self Harm, Depression, Emotion Dysregulation, Suicidal Ideation
- Trial name
- NCT03709472
- Testing
- Computer Assisted CIFFTA, Behavioral: Traditional face-to-face treatment-no technology
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- University of Miami
Depression, Suicidal Ideation
Screening Wizard- Phase 2
Screening Wizard (SW). Primary Care Providers (PCPs) are often uncertain about how to best refer adolescents who screen positive for depression or suicidality.
- Trial name
- NCT04646369
- Testing
- "screening as usual", Screening Wizard 2.0, Screening Wizard 2.0 + SOVA
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS