Clinical trials: Suicidality
Depression, Major Depressive Disorder
RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS
In this research study, investigators examine how brain activity changes during tests of emotional processing, attention, and memory using multimodal neuroimaging methods including electroencephalography (EEG), functional…
- Conditions
- Depression, Major Depressive Disorder, Suicidal Ideation
- Trial name
- NCT05977439
- Testing
- Single-Pulse Transcranial Magnetic Stimulation, EEG-Synchronized Repetitive Transcranial Magnetic Stimulation (rTMS), Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Suicidal Ideation, Depression Disorders
Acceptability and Feasibility of Reframe-IT+U for Suicidality in University Students.
Mental health in university students is a growing concern worldwide. In Chile, previous studies have shown high rates of depressive symptoms, anxiety, and suicidal risk in this population.
- Conditions
- Suicidal Ideation, Depression Disorders, Anxiety
- Trial name
- Reframe-IT+U (NCT07001202)
- Testing
- Indicated Prevention for suicidality
- Where
- Chile
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Suicide Prevention
Brief Suicide Intervention for Youth in Juvenile Detention Settings
This is an intervention development study and therefore is not designed or powered to test hypotheses. Following initial development and refinement of intervention and protocol, an open trial will be conducted at one juvenile…
- Trial name
- NCT05225103
- Testing
- SAFETY-Acute intervention
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Electrophysiological Biomarkers of AV-101
Suicide is 2-7x higher in Veterans than non-veterans, and may be related to brain kynurenine pathway (KP) dysregulation and NMDA receptor (NMDAR) hyperactivation.
- Trial name
- NCT03583554
- Testing
- AV-101 720 mg, AV-101 1440 mg
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Marijn Lijffijt, PhD
Suicidal Ideation, Suicidal and Self-injurious Behavior
Harry Potter as a Novel Educational Paradigm to Improve Mental Wellness in Children: A Prospective Trial
School-based mental health literacy interventions have been shown to reduce and/or prevent suicidal ideation and attempts. Most programs to date include an adapted version of Cognitive Behavioural Therapy (CBT) - the gold…
- Conditions
- Suicidal Ideation, Suicidal and Self-injurious Behavior, Suicide Attempt
- Trial name
- NCT04770168
- Testing
- Cognitive Behavioral Therapy Curriculum
- Where
- Canada
- Volunteers
- 3,204 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Depression, Suicidal Ideation
Engaging Black Youth in Depression and Suicide Prevention Treatment Within Urban Schools
Completing evidence-based treatments for depression has been shown to be particularly problematic for Black adolescents. If Black adolescents' depression treatment needs are to be met, the engagement challenges and the factors…
- Trial name
- NCT03940508
- Testing
- Making Connections Intervention, IPT-A
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- New York University
Suicide, Depression
Engaging Suicidal Patients in Mental Health Treatment
The investigators will identify characteristics of suicidal patients who do or do not attend a first mental health visit following referral using administrative data.
- Conditions
- Suicide, Depression, Mental Health Impairment, Suicidal Ideation
- Trial name
- NCT05021224
- Testing
- Caring Contacts, Reminders, Informational Poster
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Substance Use, Depression
Trial of Automated Risk Appraisal for Adolescents
This is a study to find out which type of computer screening and nursing support can improve screening for high risk behaviors in doctor's offices.
- Conditions
- Substance Use, Depression, Suicidal Ideation, Risk Behavior
- Trial name
- TARAA (NCT00505440)
- Testing
- Telephone case management and motivational interviewing, Usual care
- Where
- United States
- Volunteers
- 1,185 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction
Trifecta Research Study
This observational study evaluates the impact of Ibogaine-Magnesium (IM), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), Magnetic e-Resonance Therapy (MeRT), and Physiological Supplementation (PS) on posttraumatic stress disorder…
- Conditions
- PTSD - Post Traumatic Stress Disorder, Cognitive Dysfunction, Brain Injury, Depression - Major Depressive Disorder
- Trial name
- NCT07717866
- Testing
- Magnetic e-Resonance Therapy (MeRT), Ibogaine Hydrochloride with Magnesium Sulfate, 5-methoxy-N,N-dimethyltryptamine
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Axial Therapeutic Research
Depression, Suicidality
Sleep Health in U.S. Marines
The goal of this study is to test a sleep health program designed specifically for U.S. Marine Corps personnel. Researchers want to determine if this program helps Marines improve the participants sleep quality and overall mental…
- Conditions
- Depression, Suicidality, Sleep
- Trial name
- NCT07420205
- Testing
- Sleep Leadership, Circadian, Light, and Sleep Skills in Shipboard Military (CLASS-MC) Personnel Program, Insomnia Coach
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Anxiety Depression, Suicidal Ideation
Transforming Adolescent Mental Health Through Accessible, Scalable, Technology-supported Small-group Instruction
Adolescence is a developmental period of significant risk for anxiety, depressive symptoms, and suicidality, and the investigators propose to target key peer-based risk and protective factors using Cooperative Learning (CL).
- Trial name
- NCT05860257
- Testing
- PeerLearning.net
- Where
- 3 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Depression, Suicidal Ideation
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal…
- Trial name
- NCT05217706
- Testing
- Ketamine, normal Saline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rady Children's Hospital, San Diego
Psychological Distress, Suicidal Ideation
MBI for Psychological Distress, SI and NSSI Among Young Adults
Designed to measure the impact of Mindfulness Based Intervention on depression, anxiety, stress, psychological distress, Suicidal Ideation, Non-Suicidal Self Injury urge and Mindfulness in young adults.
- Conditions
- Psychological Distress, Suicidal Ideation, Non-Suicidal Self Injury
- Trial name
- NCT06263335
- Testing
- Mindfulness Based Stress Reduction Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Suicidal Ideation, Mental Health Disorder
An Autobiographical Memory-Based Intervention for Suicidality
The study involves a short therapy intervention for people who are experiencing thoughts of suicide. The intervention will focus upon different memories from the person's life.
- Trial name
- NCT06225531
- Testing
- Autobiographical Memory Based Intervention
- Where
- United Kingdom
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Lancaster University
Suicide, Suicidal Ideation
Zero Suicide Plus KICKS
Integrating Intergenerational Cultural Knowledge Exchange with Zero Suicide is an innovative study in a Southwestern tribal nation that incorporates Zero Suicide into Indian Health Services (IHS) primary care settings.
- Conditions
- Suicide, Suicidal Ideation, Suicidal Intention, Suicidal and Self-injurious Behavior
- Trial name
- NCT03924037
- Testing
- Intergenerational Knowledge Sharing group, Support group
- Where
- United States
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Suicide, Suicidal Ideation
Evaluation of a Training for Healthcare Providers in Supporting Men Experiencing Suicidal Ideation
The primary objective of this study is to assess how healthcare providers perceive and evaluate the developed e-learning. The findings will inform potential adjustments to enhance the e-learning as needed.
- Trial name
- NCT06810713
- Testing
- Gatekeeper training (e-learning)
- Where
- Belgium
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University Ghent
Suicidal Ideation, Suicide Prevention
User Evaluation Think Life
This study aims to evaluate user experiences with the online self-help course Think Life, a suicide prevention intervention for individuals experiencing suicidal thoughts.
- Conditions
- Suicidal Ideation, Suicide Prevention, mHealth Intervention
- Trial name
- NCT07654127
- Testing
- Self-help course Think Life
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University Ghent
Alaska Native Youth Aged 14 - 24, Suicide, Attempted
Suicide Intervention for Alaska Native Youth
Two interventions will be delivered virtually to American Indian/Alaska Native youth who have been hospitalized with suicidal attempt, suicidal ideation, or associated risk behaviors, including alcohol-related injury.
- Conditions
- Alaska Native Youth Aged 14 - 24, Suicide, Attempted, Suicidal Ideation, Alcohol Intoxication
- Trial name
- BeWeL (NCT05360888)
- Testing
- Tools for Life, Tools for Life + MISN
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- RAND
Mood Disorders, Suicide, Attempted
Youth Suicide Risk Factors, Reduction of Suicide Risk Factor in Youth People
The YOU-SURF project is at the forefront of youth suicide prevention, with the goal of integrating multimodal clinical and neurobiological data to comprehensively identify risk factors and the most effective intervention…
- Conditions
- Mood Disorders, Suicide, Attempted, Suicidal Ideation, Suicide Prevention
- Trial name
- YOU-SURF (NCT07188506)
- Testing
- Clinical and blood parameters, Illumina Infinium Global Screening Array 4.0 (GSA 4.0), dTMS treatment
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Depression
The Relationships of Cyber-bullying and Bullying With Mental Health Among Taiwanese Adolescents
Background and significance: Though the problem of bullying among adolescents is evidently increasing and of a serious social concern, it is often undetected until serious outcomes have surfaced.
- Trial name
- NCT02860832
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital