Clinical trials: Supplements
Hypercholesterolemia, Hyperlipidemias
Evaluation of the Effect of a Shiitake Extract on Lipid Profile in Subjects With Moderate Hyperlipidemia
Effect of a dietary supplement with Shiitake extracts (Lentinula edodes) on lipid profile and other cardiovascular risk factors in subjects with moderate hyperlipidemia without pharmacological treatment.
- Conditions
- Hypercholesterolemia, Hyperlipidemias, Dietary Supplements, Cardiovascular Risk Factor
- Trial name
- Reducol (NCT03550287)
- Testing
- Experimental product
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Supplement
A Study to Compare the Tolerability of Microencapsulated Iron Compared to a Conventional Iron Supplement in the Market
The purpose of this study is to compare the frequency of appearance of the total clinical manifestations (expected adverse event: nausea, vomiting, heartburn, abdominal pain, gas/swelling, diarrhea, headache, shortness of breath…
- Trial name
- IRON (NCT04199234)
- Testing
- Experimental product consumption, Comparator product consumption (Iron sulphate)
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Exercise Training, Carnosine
The Influence of Exercise on Tissue Beta-alanine Uptake and Carnosine Synthesis Rates
B-alanine supplementation is highly efficient in increasing intramuscular carnosine content, leading to improved physical performance, especially in high-intensity exercises (HIIE).
- Conditions
- Exercise Training, Carnosine, Dietary Supplements
- Trial name
- NCT04936737
- Testing
- Beta-alanine supplementation, High intensity interval exercise
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Resistance Training, Caffeine
Influence of Caffeinated and Non-caffeinated Pre-workout Supplements on Resistance Exercise Performance
This study is a randomized, double-blind, placebo-controlled crossover trial examining the effects of caffeinated and non-caffeinated pre-workout supplements on resistance exercise performance.
- Conditions
- Resistance Training, Caffeine, Dietary Supplements
- Trial name
- NCT04712578
- Testing
- Caffeinated pre-workout supplement, Non-caffeinated pre-workout supplement
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Cold, Cold Symptom
Ability of Beta-glucan Supplementation to Augment Immune Function
This proposed study is designed to assess the efficacy of a capsule containing beta-glucan taken orally daily as compared to a placebo capsule on the URTI symptoms, and the immune response change in marathon runners
- Conditions
- Cold, Cold Symptom, Flu, Flu Symptom
- Trial name
- NCT03769012
- Testing
- Beta-Glucan
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kemin Foods LC
Healthy, Dietary Supplement
Efficacy of Fish Oil or Olive Oil Supplementation on the Health Effects of Ozone Exposure in Healthy Young Subjects
Purpose: A growing body of epidemiological data suggests an increased risk of cardiovascular events associated with air pollution.
- Trial name
- OMEGOZ (NCT03395119)
- Testing
- Ozone, Fish Oil, Olive Oil
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Crohn's Disease, Vitamin D Deficiency
Exploring the Effects of Caltrate Supplement on the Chronic Course of Crohn's Disease Patients With Vitamin D Deficiency
Aims:Prospectively observe the effects of Caltrate supplementation on the chronic course of Crohn's disease patients, analyze whether the effect of Caltrate on CD patients is affected by factors such as disease site, disease…
- Conditions
- Crohn's Disease, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04276636
- Testing
- Caltrate Pill
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Crohn's Disease, Vitamin D Deficiency
Exploring the Effects of Vitamin D Supplementation on the Chronic Course of Patients With Crohn's Disease With Vitamin D Deficiency
Aims:Prospectively observe the effects of Vitamin D drops supplementation on the chronic course of Crohn's disease patients, analyze whether the effect of Vitamin D drops on CD patients is affected by factors such as disease…
- Conditions
- Crohn's Disease, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04308850
- Testing
- Vitamin D drops
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Multiple Sclerosis, Exercise Therapy
Carnosine Loading and Periodized Training in MS and HC
Increasing evidence favours exercise therapy as an efficient tool to counteract inactivity related secondary symptoms in MS. Furthermore, exercise therapy may affect MS-associated muscle contractile and energy supply…
- Conditions
- Multiple Sclerosis, Exercise Therapy, Dietary Supplement
- Trial name
- NCT03418376
- Testing
- Beta-alanine supplementation, Exercise intervention
- Where
- Belgium
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Infant, Dietary Supplements
Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants.
- Conditions
- Infant, Dietary Supplements, Food, Fortified
- Trial name
- MJAU (NCT01216709)
- Testing
- ferrous sulfate, iron-fortified infant formula (12.4 mg iron/L), iron-fortified infant formula (2.3 mg iron/L)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umeå University
Dietary Supplement: Ketone Supplement, Dietary Supplement: Placebo
The Effects of Exogenous Ketones on Glucose Tolerance
The ketone body beta-hydroxybutyrate is produced during prolonged fasting or when endogenous carbohydrate stores are depleted and can be used as an alternative fuel source.
- Trial name
- NCT04088617
- Testing
- Ketone monoester
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ulcerative Colitis, Vitamin D Deficiency
Observation of the Effect of Vitamin D Supplementation on Chronic Course of Patients With Ulcerative Colitis Based on Vitamin D Receptor Fok I Gene Polymorphism
Aims:Prospectively observe the effects of Vitamin D drops supplementation on the chronic course of ulcerative colitis patients, analyze whether the effect of Vitamin D drops on UC patients is affected by factors such as disease…
- Conditions
- Ulcerative Colitis, Vitamin D Deficiency, Vitamin D Supplement
- Trial name
- NCT04309058
- Testing
- Vitamin D drops
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Dietary Supplement, Sport Performance
Beetroot Juice Supplementation in Basketball Players
Whereas beetroot juice (BJ) supplementation is shown to increase physical performance in endurance activities, its benefits in team sports has been barely studied.
- Trial name
- NCT04210531
- Testing
- Beetroot juice (BJ) acute supplementation
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
To Study the Effects of Protein Supplements on Blood Tests
Do High Doses of Protein Supplements Affect Serum Lipid Profiles?
Protein supplements are widely used among people going to the gym. The effects of these substances on blood biochemical, hematological, inflammatuary, glucose metabolism markers and lipid profile is not well known.
- Trial name
- NCT04170036
- Testing
- protein supplement
- Where
- Cyprus
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Dietary Supplement
Probiotics in Children With Early Childhood Caries
The purpose of this study is to determine if probiotic lozenges taken once a day before bedtime for twelve weeks can decrease the numbers of Streptococcus mutans
- Trial name
- NCT03998306
- Testing
- Experimental: Probiotics, No intervention
- Where
- Poland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Nutritional Supplement Toxicity
Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People (KnoVIB)
The standard recommendation to prevent osteoporosis is to supplement low doses of vitamin D and calcium. Hyperhomocysteinemia has been related to increased risk of osteoporosis.
- Trial name
- KnoVIB (NCT02586181)
- Testing
- Vitamin D and Calcium, Vitamin D, Calcium, Vitamins B9, B6, B12
- Where
- Germany
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes
Medication and Supplement Use, Pregnant Women
A Cross-sectional Study Evaluating Pregnancy Related Use of Vitamins and Medication
This cross-sectional study will try to give answers to the following project aims: To provide an overview of the prevalence of health products' use among Belgian pregnant women (prescription and OTC medication, vitamin…
- Trial name
- PREVIM (NCT03105583)
- Testing
- Medication use during pregnancy, Supplement use during pregnancy, Vitamin status of a pregnant woman
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Dietary Supplements
Muscadine Grape Seed Supplementation and Vascular Function
The investigators sought to evaluate the effect of muscadine grape seed supplementation on brachial diameter and flow-mediated vasodilator responses in subjects with, or at risk for cardiovascular disease.
- Trial name
- NCT01011517
- Testing
- Muscadine grape seed supplement
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Dietary Supplements
Effects of Genetic Variations in the Response to Brazil Nut Supplementation
This study investigates the effect of genetic variations after supplementation with Brazil nuts in healthy Brazilians. Briefly, all the participants will consume one nut a day for 2 months and will stop the intake for more 2…
- Trial name
- SUBRANUT (NCT03111355)
- Testing
- Brazil nut
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dietary Supplements, Bleeding Tendency; Due to Coagulation Defect
ROTEM and Dietary Supplements
Dietary Supplements can affect platelet activation and aggregation, which could result in bleeding tendencies. This study wishes to evaluate the influence that these supplements has on platelet function using Rotational…
- Trial name
- NCT03125551
- Testing
- Ginger, Garlic, Ginkgo Biloba
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pretoria