Clinical trials: Supplements
Oral Health, Dietary Nitrate
Evaluating the Impact of Various Dietary Nitrate Supplements on Oral Health
This study aims to investigate the effects of different dietary nitrate supplements, versus placebo, on microbiological and immunological markers associated with oral health in people aged 18-65 years.
- Trial name
- NCT06956612
- Testing
- Juice (Active comparator), Crystals (Experimental)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shatha Alhulaefi
Healthy
Effectiveness of an Internet-Based Curriculum in Increasing Health Care Providers' Knowledge of Herbs and Dietary Supplements
The purpose of this study is to determine the effectiveness of four different strategies designed to improve clinicians' knowledge about herbs and dietary supplements.
- Trial name
- NCT00110539
- Testing
- Complementary and alternative medicine education
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Library of Medicine (NLM)
Food-drug Interaction
Red Clover Botanical Dietary Supplements - Metabolism and Safety in Women
Human safety studies were carried out to test whether red clover botanical dietary supplements used by peri- and post-menopausal women are safe to use with Food and Drug Administration (FDA)-approved drugs.
- Trial name
- NCT03205787
- Testing
- Trifolium pratense
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Overweight and Obesity, Inflammation
Clinical Trials of Five Different Food Supplements With Restriction Diet in Adults
In recent years, dietary supplement are of great interest for the improvement of human health. This study is designed as a parallel, randomized, double blind study exploring the efficacy of two months daily oral dosing of five…
- Conditions
- Overweight and Obesity, Inflammation, Hypercholesterolemia, Hypertension
- Trial name
- FOODSU (NCT05333315)
- Testing
- IP1, IP2, IP3
- Where
- Slovenia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Climacteric Syndrome, Menopause
Clinical Evaluation of Effectiveness and Safety of Amberen and Smart B by Women With Climacteric Syndrome
To evaluate effectiveness and safety of combined use of dietary supplements Amberen and Smart B by women with a typical (without complications) form of climacteric syndrome, with mild to moderate symptoms.
- Trial name
- NCT03118908
- Testing
- Amberen, Smart B
- Where
- Russia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Dental Caries, Gingivitis
Effect of a 2-week Sugar Stress on Bacterial Profiles in Whole Saliva
Dental caries is a non-communicable biofilm-mediated disease affecting both crown and exposed root surfaces in the primary and permanent dentitions.
- Trial name
- NCT04199897
- Testing
- Succrose rinsing, Probiotic lozenges, xylitol rinsing
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Iron-deficiency, Iron Deficiency Anaemia Due to Dietary Causes
Effect of Iron Supplements on the Growth of Enteric Pathogens
Iron supplementation is a common approach to address iron deficiency with recommendations for women of childbearing age, particularly those at risk of iron deficiency.
- Conditions
- Iron-deficiency, Iron Deficiency Anaemia Due to Dietary Causes, Iron Deficiency Anemia Treatment, Iron Deficiency Anemia
- Trial name
- NCT05762380
- Testing
- Ferrous sulfate, Ferrous sulfate-enriched Aspergillus oryzae (Ao iron)
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Exercise
Dietary Supplements and Exercise in Aging Adults
The purpose of this study is to determine the effects of food supplements and strength training on appetite, the amount of energy used, and body composition.
- Trial name
- NCT00761553
- Testing
- Dietary supplements with exercise, Dietary supplement without exercise
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Purdue University
Exercise Training, Carnosine
The Influence of Exercise on Tissue Beta-alanine Uptake and Carnosine Synthesis Rates
B-alanine supplementation is highly efficient in increasing intramuscular carnosine content, leading to improved physical performance, especially in high-intensity exercises (HIIE).
- Conditions
- Exercise Training, Carnosine, Dietary Supplements
- Trial name
- NCT04936737
- Testing
- Beta-alanine supplementation, High intensity interval exercise
- Where
- Brazil
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypertension, Type 2 Diabetes
Military Health and Nutrition Examination Study
The Military Health and Nutrition Examination Study (MHANES) is a Department of Defense funded study conducted by Pennington Biomedical Research Center and the US Army Research Institute of Environmental Medicine.
- Conditions
- Hypertension, Type 2 Diabetes, Dyslipidemias, Cardiovascular Diseases
- Trial name
- MHANES (NCT06380322)
- Where
- 6 sites in United States
- Volunteers
- 648 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Healthy Participants
Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements in ACPA+ Individuals
The goal of this clinical trial is to determine if the level of Anti-cyclic citrullinated peptide antibody (ACPA) is altered after taking curcumin, omega-3, and vitamin D supplements (COD) for 3 months.
- Trial name
- PASCOD3 (NCT06478290)
- Testing
- curcumin, omega-3, and vitamin D (COD)
- Where
- 2 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Vitamin D Deficiency, Vitamin; Excess Vitamin D (Nutritional)
Vitamin D Supplements on Markers for Cardiovascular Disease and Diabetes: an Individual Participant Data Meta-analysis
This meta-analysis will be conducted to study the effect on vitamin D supplements on markers for cardiovascular disease and diabetes using individual participant data from 12 RCTs.
- Trial name
- NCT02551835
- Volunteers
- 2,945 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Pre-Eclampsia, Hypertension, Pregnancy-Induced
Low Dose Calcium to Prevent Preeclampsia
The purpose of this study is to assess, in pregnant women with calcium-poor diets, what is the effectiveness of low-dose (500 mg/day) calcium supplements associated with an educational intervention, compared to the educational…
- Conditions
- Pre-Eclampsia, Hypertension, Pregnancy-Induced, Dietary Calcium Deficiency
- Trial name
- AMCAL (NCT02338687)
- Testing
- calcium, Educational sessions
- Where
- Brazil
- Volunteers
- 1,040 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Cardiovascular Diseases, Cardiovascular Abnormalities
The Effects of the Dietary Supplement CardioFlex Q10 on Reducing Cardiovascular Disease Risk Factors in Adults
Cardiovascular diseases (CVD), primarily heart disease and stroke, are the leading causes of death and prescription drug use in Canada.
- Conditions
- Cardiovascular Diseases, Cardiovascular Abnormalities, Heart Attack, Stroke
- Trial name
- NCT03826914
- Testing
- CardioFlex Q10
- Where
- Canada
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Glycogen Storage Disease Type III
Energy Supplements to Improve Exercise Tolerance in Metabolic Myopathies
Patients suffering from the metabolic myopathy Glycogen Storage Disease type IIIa (GSDIIIa) have a problem releasing sugar stored in cells that is needed for energy production.
- Trial name
- NCT02448667
- Testing
- FAXE Kondi, Faxe Kondi Free
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Ketonemia, Mental Fatigue
Exogenous Ketone Supplementation and Cognitive Function During Exercise
15 healthy trained males will volunteer to participate in this study. there will be 2 treatments: Ketone esters supplementation and iso-caloric carbohydrate.
- Conditions
- Ketonemia, Mental Fatigue, Ketosis
- Trial name
- NCT04576026
- Testing
- mental fatiguing task, 45 - minute simulated soccer game, cognitive function
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Healthy
Study Comparing Two Isoforms of Vitamin D Supplements for Infants
There are two different types of vitamin D - vitamin D3 (animal source) and vitamin D2 (plant source). Almost all the usual vitamin D preparations for infants available in Canadian pharmacies contain vitamin D3 which may not be…
- Trial name
- NCT01190137
- Testing
- Cholecalciferol (D3) or ergocalciferol (D2)
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- McGill University
Cytokine Storm
The Effect of D3 on Selected Cytokines Involved in Cytokine Storm in the Covid-19 Uninfected Jordanian People
The effect of Weekly 50,000 IU vitamin D3 supplements on the serum levels of selected cytokines involved in cytokine storm of Covid-19; A randomized clinical trial in the Covid-19 uninfected people with vitamin D deficiency.
- Trial name
- NCT04476745
- Testing
- Vitamin D3
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Applied Science Private University
Male Infertility
Supplementation for Male Subfertility
Old age, obesity, physical inactivity, environmental factors and genetics may contribute negatively to fertility in both males and females.
- Trial name
- FertEnhancer (NCT06091969)
- Testing
- Active multi-ingredient supplement (Fertility Enhancer, FE)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Cardiovascular Disease
Effects of Resveratrol Supplements on Vascular Health in Postmenopausal Women
The investigators hope to learn if resveratrol supplementation can be beneficial for the cardiovascular system. Seeing that resveratrol is rapidly metabolized, the investigators are interested in learning if a novel form of…
- Trial name
- NCT01564381
- Testing
- ResA, Resveratrol
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of California, Davis