Clinical trials: Surgery Indication
Chronic Pain
Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain
The purpose of this study is to obtain real-world clinical outcome data for the Algovita Spinal Cord Stimulation system when used, on-label, according to the applicable directions for use.
- Trial name
- NCT02373540
- Testing
- Algovita Spinal Cord Stimulation system
- Where
- 18 sites in United States, Germany
- Volunteers
- 91 people
- Sponsor
- Nuvectra
Liver Neoplasms, Sarcopenia
Impact of Sarcopenia on Postoperative Outcomes of Patients Undergoing Liver Resection
The investigators will investigate the impact of different biometric parameters (Body mass index, sarcopenia, lean muscle mass, hand-grip strength, gait speed, fat composition) on the postoperative outcomes of patients undergoing…
- Conditions
- Liver Neoplasms, Sarcopenia, Postoperative Complications
- Trial name
- NCT03630978
- Testing
- Liver resection
- Where
- Italy
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- San Camillo Hospital, Rome
Internal Carotid Stenosis
Medico-economic Evaluation of Preoperative Cerebral Oximetry Monitoring During Carotid Endarterectomy
In France, in 2007, 17 000 patients underwent carotid endarterectomy. The risk of having an ipsilateral postoperative stroke after carotid endarterectomy remains at 1-1.5%.
- Trial name
- EMOCAR (NCT01415648)
- Testing
- cerebral oximetry monitoring using INVOS™ and hemodynamic optimisation, standard cerebral monitoring and hemodynamic optimisation
- Where
- 19 sites in France
- Volunteers
- 879 people
- Sponsor
- Nantes University Hospital
Thyroid Node, Indeterminate Cytology
Diagnostic Value of Molecular Cytological Analysis (CMA) and Shear Wave Elastography ShearWave (SWE) in Patients With a Thyroid Nodule With Indeterminate Cytology: Feasibility Study
The purpose of the study is to investigate the contribution of molecular cytological analysis (CMA) and shear wave elastography ShearWave (SWE) in the diagnosis of nodules with indeterminate cytology (IC)
- Conditions
- Thyroid Node, Indeterminate Cytology, Surgery Indication
- Trial name
- SWEETMAC (NCT01880203)
- Testing
- aspiration in thyroid node for Molecular Cytogenetic Analysis.
- Where
- 4 sites in France
- Volunteers
- 140 people
- Sponsor
- Centre Francois Baclesse
Moderate to Severe Hearing Loss, Indication of Middle Ear Implant (MET)
Surgical Optimizing of a Middle Ear Implant (MET )With Laser Velocimetry in Patients With Moderate to Severe Hearing Loss in Case of Failure of Conventional Equipment
The aging of the population, and greater exposure to noise, are responsible for an increased incidence of hearing loss (presbycusis). This hearing loss is sensorineural disability that has become a real public health problem.
- Trial name
- IOM laser (NCT02845115)
- Testing
- Conventional implantation, optimized implantation with laser velocimetry
- Volunteers
- 2 people
- Sponsor
- Hospices Civils de Lyon
Patient With Ascending Aortic Aneurysm With Surgical Indication for Replacement
Prospective Evaluation of the Biomechanical Properties of the Thoracic Aorta Coupling Magnetic Resonance Imaging and In-vitro Elasticity Tests in Patients With Ascending Aortic Aneurysm
The biomechanical properties of the aorta are currently poorly understood. A better understanding would optimize surgical indications and monitoring techniques for patients with thoracic aortic aneurysms.
- Trial name
- MECATHOR (NCT03746964)
- Testing
- Cardiac MRI, in-vitro elasticity tests
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Indication for Laparoscopic Surgery (Any)
Prospective Evaluation of the Use of Thunderbeat Vessel Sealing Device in Laparoscopic Surgery
All patients undergoing laparoscopic visceral and gynecologic procedures using the combined bipolar and ultrasonic vessel sealing and dissection device Thunderbeat are entered in a prospective registry.
- Trial name
- NCT01999296
- Testing
- Use of Thunderbeat (TM) in laparoscopic surgery
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Cantonal Hospital, Baselland
Rheumatoid Arthritis, Osteoarthritis
A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
The purpose of this study is to monitor the performance and determine the metal ion release of the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872794
- Testing
- DePuy ASR™ Hip System
- Where
- South Africa
- Volunteers
- 50 people
- Sponsor
- DePuy International
Breast Cancer Surgery
Comparison of Conventional With Sonography Assisted Breast Surgery After Neoadjuvant Chemotherapy
Aim of the study is to investigate whether intra-surgical visualisation of malignoma reduces the resection rate in the case of R1 resection compared to the procedure without sonographic visualisation
- Trial name
- NCT03737266
- Testing
- Sonographically assisted breast surgery, Conventional breast surgery
- Where
- Germany
- Volunteers
- 137 people
- Sponsor
- University Hospital Tuebingen
Indication for Surgery of the Posterior Segment Under Locoregional Anaesthesia
Clonidine - Ropivacaine in Peribulbar Anesthesia
This is a study conducted in 60 patients, randomly assigned to one of two groups of 30: the first will receive ropivacaine alone and the second will receive the association ropivacaine/clonidine.
- Trial name
- CRAPO (NCT01963299)
- Testing
- 5 ml Ropivacaine 10% + physiological saline, 5 ml Ropivacaine 10% + Clonidine 1 µg/kg
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Description of an Effective Surgical Strategy to Treat Cancer-related Lymphedema, Combination of LVA and Liposuction Guarantees Long Lasting Results
Combination of Lymphatico-venular Anastomosis and Liposuction to Treat Cancer-related Lymphedema
cooperation of an International team with many years of experience in surgical management of lymphedema description of an effective surgical strategy to treat cancer-related lymphedema, a high incidence pathology the combination…
- Trial name
- NCT05025982
- Testing
- combination of lymphaticovenular anastomosis and liposuction
- Where
- 2 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Siena
Low Back Pain, Lumbar Spine Injury
Second Opinion in Spinal Surgery Indications: Cost-Effectiveness Evaluation
Low back pain is a common symptom, which often affects the adult population. Studies show that over the past two decades, costs related to spinal surgery have increased significantly, leading to speculation about what would be…
- Trial name
- NCT03082248
- Testing
- Physical Therapy, Spinal Surgery
- Where
- Brazil
- Volunteers
- 190 people
- Sponsor
- Hospital Israelita Albert Einstein
Minimally Invasive Surgical Procedures, VATS
Prolonged Hospital Stay After Thoracoscopic Anatomical Lung Resections
In this study, the reasons for prolonged hospital stay after thoracoscopic (video- or robot-assisted) anatomical lung resections are investigated.
- Conditions
- Minimally Invasive Surgical Procedures, VATS, RATS Surgery, Pulmonary Lobectomy
- Trial name
- PROTRACT (NCT06638645)
- Testing
- VATS/RATS anatomical lung resection
- Where
- 2 sites in Belgium
- Volunteers
- 140 people
- Sponsor
- University Hospital, Ghent
Nasal Obstruction
Evaluation of the Reliability of AAR as an Independent Tool for Surgical Indication in Nasal Obstruction
Nasal obstruction (NO) affects ~30% of the population and is a very common reason for consultation in otorhinolaryngology (ORL).
- Trial name
- RHINOVE (NCT07379775)
- Testing
- preoperative rhinomanometry
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Transbronchial Surgery, Lymph Node Disease
Evolution of Indications for Transbronchial Ganglionic Ultrasound
New indications for bronchial echo-endoscopies with transbronchial needle aspiration (EBUS-PTBA) have appeared since the first French centers with this technique were fitted.
- Trial name
- EBUSPicardie (NCT03132883)
- Where
- France
- Volunteers
- 1,036 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Upper Limb Wound, Lower Limb Wound
Wide-awake Local Anesthesia and no Tourniquet (WALANT) in Plastic Surgery
Wide-awake local anesthesia no tourniquet (WALANT) was proposed and performed in hand operations. Aim of this study is to present the use of WALANT in operations performed on the upper and lower limbs, evaluate its efficacy in…
- Conditions
- Upper Limb Wound, Lower Limb Wound, Anesthesia, Local
- Trial name
- NCT04992351
- Testing
- WALANT
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ioannina
Ulcerative Colitis, Inflammatory Bowel Diseases
Complications and Outcomes of Pouch Excision
Procedure is offered today to most patients with chronic ulcerative colitis (CUC) or familial adenomatous polyposis (FAP) who are candidates for total proctocolectomy.
- Trial name
- NCT03952195
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Degeneration Spine, Spine Deformity
Reasons and Risk Factors for Unplanned Spinal Re-operation
Unplanned re-operation is one of the common negative indicators reflecting the quality and safety of surgery in the medical industry and has become one of the ten goals for the improvement of national medical quality and safety…
- Conditions
- Degeneration Spine, Spine Deformity, Spine Tumor, Spine Fracture
- Trial name
- NCT05995327
- Where
- 5 sites in China
- Volunteers
- 70,000 people
- Sponsor
- Peking University Third Hospital
Blood Disease, Anemia
Anemia and Surgery: Indications For Transfusion
To estimate the risk of death for patients with different pre- and post-operative hemoglobin levels who do not receive blood transfusions and to derive a multivariate model using clinical information available pre-operatively…
- Trial name
- NCT00005308
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)