Clinical trials: Surgery for Colorectal Cancer.
Rectal Cancer, Left Colic Artery Stenosis (Diagnosis)
Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation
Brief Summary Background The preservation of the left colic artery (LCA) during rectal cancer resection remains a topic of controversy, and there is a notable absence of robust evidence regarding the outcomes associated with LCA…
- Conditions
- Rectal Cancer, Left Colic Artery Stenosis (Diagnosis), Robotic Assisted Laparoscopic Surgery
- Trial name
- NCT06376227
- Testing
- with or without Left Colic Artery Preservation
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Northern Jiangsu People's Hospital
Colorectal Cancer
A Multicenter Study on the Safety and Functionality Evaluation of Anastomotic Redo Surgery
To analyze the influencing factors of the success of redo surgery due to anastomotic fistula or anastomotic recurrence after rectal cancer surgery and to evaluate the anal function of patients
- Trial name
- NCT07279961
- Volunteers
- 143 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Rectal Cancer
Laparoscopic Assisted Transanal Total Mesorectal Excision for Rectal Cancer in Low Site
At present, surgical resection is still the main treatment for the potential cure of rectal cancer. Total mesorectal excision (TME) is the gold standard.
- Trial name
- LATERAL-01 (NCT03253302)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Friendship Hospital
Rectal Cancer
Closure of Protective Ileostomy 2 vs. 12 Weeks After TME
The purpose of this study is to compare the feasibility, safety, and quality of life (QOL) in patients (pts) undergoing protective ileostomy closure after 2 weeks with a closure after 12 weeks.
- Trial name
- Closure2vs12 (NCT02609451)
- Testing
- Ileostomy closure
- Where
- Switzerland
- Volunteers
- 71 people
- Sponsor
- Kantonsspital Liestal
Synchronous Isolated Para-aortic Lymph Node Metastasis, Colorectal Cancer
Systemic Therapy Sequenced Isolated PALND for mCRC
The study aims to estimate the efficacy and safety of systemic therapy sequenced radical surgery in treating patients with synchronous isolated para-aortic lymph node metastasis of colorectal cancer.
- Trial name
- NCT04774757
- Testing
- Para-aortic lymph node dissection
- Where
- China
- Volunteers
- 39 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Colorectal Cancer, Nutrition Aspect of Cancer
Immunonutrition for Prehabilitation of Patients With Colorectal Cancer Before Surgery
Perioperative immunonutrition has been proposed as a strategy to modulate the inflammatory response and improve outcomes after colorectal surgery.
- Trial name
- IMNUTPREH-CRC (NCT07653737)
- Testing
- Oral nutritional supplement with inmmunonutrition, Standard oral nutritional supplement
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Colorectal Cancer, Inflammatory Bowel Diseases
Home To Stay: a Randomized Trial Evaluating a Post-discharge Mobile App for Elective Colorectal Surgery
A single center randomized controlled trial to evaluate the effect of a post-discharge mobile health application on 30-day re-admission and patient reported outcomes following elective colorectal surgery
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Utilization, Health Care, Surgery
- Trial name
- NCT04968145
- Testing
- Home To Stay Mobile Health Application
- Where
- Canada
- Volunteers
- 282 people
- Sponsor
- Division of General Surgery , Mt. Sinai Hospital
Rectal Cancer
The Evaluation of the Safety and the Efficacy of Transanal Total Mesorectal Excision
The purpose of this study is evaluation of the safety and the efficacy of transanal total mesorectal excision.
- Trial name
- NCT01938027
- Testing
- Transanal total mesorectal excision
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- National Cancer Center, Korea
Colo-rectal Cancer
EMVI as a Determinant of Metastasis in Colorectal Cancer
Bowel cancer is the fourth most commonly occurring cancer and the second highest cause of cancer deaths in the UK. Despite advances in treatment, over 40% of patients will die within 5 years.
- Trial name
- EVIDENCE (NCT06646341)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Harm Reduction, Perforation During Colonoscopy
Fast Track Module Based Colonoscopy Training Programme for Surgical Trainees at North Jutland Surgical Departments
Specially educated trainers will be responsible for colonoscopy training of junior doctors. The educated trainers will have attended seminars held by Valori et al.
- Conditions
- Harm Reduction, Perforation During Colonoscopy, Colorectal Cancer
- Trial name
- NCT02425657
- Testing
- Training of junior doctors
- Where
- 3 sites in Denmark
- Volunteers
- 15 people
- Sponsor
- Aalborg University Hospital
Colonic Neoplasms
Five Year Oncological Outcome After CME for Right-sided Colon Cancer
Study based on existing databases investigating the causal oncological treatment effects of complete mesocolic excision on UICC stage I-III right-sided colon cancer.
- Trial name
- NCT03754075
- Testing
- Complete mesocolic excision, Conventional colon resections
- Volunteers
- 1,069 people
- Sponsor
- Nordsjaellands Hospital
Colon Cancer
The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer
The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.
- Trial name
- NCT05859581
- Testing
- Beyond complete mesocolic excision surgery
- Where
- China
- Volunteers
- 29 people
- Sponsor
- Peking University Cancer Hospital & Institute
Colon Cancer, Colon Cancer (Stage II &Amp;Amp;Amp; III)
ctDNA-guided Selection of Adjuvant Chemotherapy Regimens for Elderly Colon Cancer Patients After Surgery: A Single-center, Randomized, Controlled Study
The goal of this clinical trial is to explore the disease-free survival period of elderly patients with high-risk stage II and stage III colon cancer based on ctDNA detection.
- Trial name
- ZJCH-CRCC-1 (NCT06609551)
- Testing
- 6-month adjuvant chemotherapy with 5-FU monotherapy, XELOX intensive treatment group
- Where
- China
- Volunteers
- 312 people
- Sponsor
- Zhejiang Cancer Hospital
Colorectal Cancer, Colorectal Carcinoma
The Problem of Colorectal Anastomosis Safety
This is a prospective cohort pilot study. The investigators are planning to develop an original, standardized colorectal anastomosis inspection method, which will systemically inspect the anastomosis vascularity using the…
- Conditions
- Colorectal Cancer, Colorectal Carcinoma, Colorectal Neoplasms, Colorectal Adenocarcinoma
- Trial name
- ANSCRS (NCT03958500)
- Testing
- Indocyanine green fluorescent angiography intraluminally and intraperitoneally
- Where
- 2 sites in Lithuania
- Volunteers
- 60 people
- Sponsor
- Vilnius University
Colorectal Cancer, Neoadjuvant Chemotherapy
Neoadjuvant Chemotherapy Verse Surgery Alone After Stent Placement for Obstructive Colonic Cancer
Colorectal cancer is the fourth most common cancer in China. Up to 30% of patients with colorectal cancer present with an emergency obstruction of the large bowel at the time of diagnosis, and 70% of all malignant obstruction…
- Conditions
- Colorectal Cancer, Neoadjuvant Chemotherapy, Stent, Obstruction
- Trial name
- NACSOC (NCT02972541)
- Testing
- Stenting with neoadjuvant chemotherapy, Stenting with immediate Surgery
- Where
- 32 sites in China
- Volunteers
- 248 people
- Sponsor
- Beijing Chao Yang Hospital
Colon Cancer, Rectum Cancer
Phase I of SGM-101 in Patients With Cancer of the Colon, Rectum or Pancreas
This study evaluates the safety and performance of SGM-101, a Carcinoembryonic Antigen (CEA)-specific chimeric antibody conjugated with a NIR emitting fluorochrome, for the visualization of CEA-expressing cancers during surgery.
- Conditions
- Colon Cancer, Rectum Cancer, Pancreas Cancer, Metastatic Colorectal Cancer
- Trial name
- NCT02973672
- Testing
- SGM-101
- Where
- 3 sites in Netherlands
- Volunteers
- 75 people
- Sponsor
- Surgimab
Colorectal Cancer (MSI-H), Postoperative Delirium (POD)
POD Risk for Colorectal Cancer Surgery
Postoperative delirium is a common complication after colorectal cancer surgery that hinders recovery. This observational study hypothesizes that a simple, practical risk tool can be developed by combining preoperative clinical…
- Trial name
- NCT07597330
- Where
- China
- Volunteers
- 590 people
- Sponsor
- LanZhou University
Colorectal Cancer
Prospective Study on the Efficacy and Safety of 2 Week or 3 Week Xelox Regimen for Adjuvant Chemotherapy in CRC
This study select the diagnosis of postoperative colorectal cancer patients with stage II/III to adjuvant chemotherapy, and received 2 weeks and 3 weeks xelox adjuvant treatment process until disease progression or patients died…
- Trial name
- NCT03564912
- Testing
- Capecitabine Oral Tablet [Xeloda]
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Zhejiang University
Colorectal Cancer
Fluorouracil and Irinotecan With or Without Leucovorin Compared With Observation in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer
RATIONALE: Drugs used in chemotherapy, such as irinotecan, leucovorin, and fluorouracil, work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00091312
- Testing
- FOLFIRI regimen, fluorouracil, irinotecan hydrochloride
- Where
- 9 sites in Egypt, France and 4 more
- Volunteers
- 1,976 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Rectal Cancer, Rectal Adenocarcinoma
SCARLET - Italian proSpeCtionAl obseRvationaL multicEntre Study on Treatment for recTal pT1 Cancer
The purpose of this prospective, observational, multicenter study is to evaluate the impact of adjuvant radiotherapy or chemoradiotherapy on disease-free survival (DFS) in patients with pathological T1 (pT1) rectal cancer…
- Conditions
- Rectal Cancer, Rectal Adenocarcinoma, Rectal Cancer Patients, Rectal Cancer, Radiotherapy
- Trial name
- SCARLET (NCT07695519)
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS