Clinical trials: Surgery of Breast Cancer
Hereditary Breast and Ovarian Cancer Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis
Risk-Reducing Surgeries for Hereditary Ovarian Cancer
Based on studies of "Inherited Susceptible Genes Among Epithelial Ovarian Cancer" (NCT03015376, clinicaltrials.gov) and "Cohort Study of Universal Screening for Lynch Syndrome in Chinese Patients of Endometrial Cancer"…
- Conditions
- Hereditary Breast and Ovarian Cancer Syndrome, Colorectal Neoplasms, Hereditary Nonpolyposis, Ovariectomy, Hysterectomy
- Trial name
- NCT03294343
- Testing
- salpingo-oophorectomy only by laparoscopy, salpingo-oophorectomy with hysterectomy by laparoscopy, Follow-up
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Lei Li
Breast Cancer
BREAST Choice Decision Tool R21 - AIM2
Breast reconstruction is a critical component of breast cancer treatment because it restores quality of life and body image after mastectomy.
- Trial name
- BREASTChoice (NCT06817226)
- Testing
- Pre-survey, BREASTChoice tool., Post-survey
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Braest Cancer, Breast Reconstruction
Evaluating the Effectiveness of an Early Exercise Program After Breast Reconstruction
Breast reconstruction is an important step and option after mastectomy and can help improve the quality of life of breast cancer patients.
- Trial name
- NCT06552650
- Testing
- Exercise, Usual Care
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Pain
Efficacy of Tramadol With Ropivacaine for Modified Pectoral Nerve Block in Breast Cancer Surgery
In this study the investigators will compare the post operative opoid consumption for patient undergoing modified radical mastectomy.
- Trial name
- NCT07775053
- Testing
- Pectoral Nerve Block
- Where
- Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sargodha Medical College
Laughter Therapy, Psychological Well-being
Effect of Laughter Therapy on Breast Cancer Patients
The aim of this study is to examine the effect of laughter therapy applied to breast cancer patients before surgical intervention on distress, depression and psychological well-being of patients.
- Conditions
- Laughter Therapy, Psychological Well-being, Breast Cancer, Distress
- Trial name
- NCT07020962
- Testing
- laughter therapy, routine nursing care
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Tumor, Brain, Tumor, Breast
Microscopy Imaging of Whole-mount Stained Human Tissues
The goal of this clinical trial is to develop an imaging platform for intraoperative tumor margin delineation in 250 cases of tumor-suffered patients.
- Conditions
- Tumor, Brain, Tumor, Breast, Tumor Skin
- Trial name
- NCT05689112
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Breast Cancer, Radiation Dermatitis
A DB Randomized Study of R1 and R2 WaterJel / AloeVera Jell in Prevention of Radiation Dermatitis in Breast Cancer
The purpose of this study is to evaluate the effects of topical R1 and R2 for prophylaxis of acute radiation dermatitis in patients with breast cancer receiving radiotherapy.
- Conditions
- Breast Cancer, Radiation Dermatitis, Erythema
- Trial name
- NCT01597921
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Water-Jel
Breast Carcinoma
Stakeholder Assessment of Implementing the Commission on Cancer Operative Standards for Cancer Surgery
This study investigates the barriers to implementing breast Synoptic Operative Reports. Information from this study may help researchers identify performance objectives for the breast Synoptic Operative Reports to be adopted…
- Trial name
- NCT05583981
- Testing
- Interview
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Breast Neoplasm Female, Pain, Postoperative
Effectiveness of Ultrasound Guided PECS Block on Opioid Consumption and Patient Satisfaction Through Adequate Pain Control Following Breast Cancer Surgery.
Breast cancer is the most common and leading cause of cancer deaths among females worldwide. Patients undergoing modified radical mastectomy (MRM) are associated with moderate to severe acute postoperative pain and shoulder…
- Conditions
- Breast Neoplasm Female, Pain, Postoperative, Pain, Analgesia
- Trial name
- NCT04343807
- Testing
- PECS Block, Control Group
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Breast Neoplasms, Breast Cancer
External Hypofractionated Radiotherapy With Simultaneous Integrated Boost in Early Breast Cancer Patients
This is a prospective non randomized phase two trial evaluating the feasibility of a ten fraction accelerated hypofractionated radiotherapy schedule with simultaneous integrated boost risk adapted in patients undergoing breast…
- Trial name
- ESIBIRE (NCT06224244)
- Testing
- Ten-fraction hypofractionated breast radiotherapy with 40 Gy simultaneous integrated bed boost, Ten-fraction hypofractionated breast radiotherapy with 43 Gy simultaneous integrated bed boost
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Regina Elena Cancer Institute
Mastectomy, Mastectomy Patient
A Study on Pain After Breast Reconstruction
The purpose of this study is to find out how common persistent postmastectomy pain (PPMP) is among people who have had a mastectomy and breast reconstruction surgery for their breast cancer.
- Conditions
- Mastectomy, Mastectomy Patient, Mastectomy and Breast Reconstruction, Breast Reconstruction
- Trial name
- NCT06627582
- Testing
- PROMIS Scale v2.0 - Pain Intensity 3a, PROMIS 29+2, PROMIS Scale v2.0 - Nociceptive Pain Quality 5a
- Where
- 7 sites in United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Hemodynamic Instability, Opioid Use
Effects of US-guided SAPB During Breast Surgery
The serratus anterior plan (SAP) block is a technique that has recently gained popularity in the context of breast surgery. SAP block resulted in better hemodynamic stability, early ambulation and shorter hospital stay, as well…
- Conditions
- Hemodynamic Instability, Opioid Use, Block, Breast Cancer
- Trial name
- NCT04824833
- Testing
- Serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Primary Operable Breast Cancer
Perioperative Administration of COX 2 Inhibitors and Beta Blockers to Women Undergoing Breast Cancer Surgery
Surgery for breast cancer has a major role in enhancing long term survival and cure, but several physiological aspects associated with surgery are implicated as enhancing tumor spread and formation of distant metastases.
- Trial name
- NCT00502684
- Testing
- Propranolol, etodolac
- Where
- 3 sites in Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Breast/Surgery
Nipple-sparing Mastectomy in Combined With Buried Flap Monitoring
1. Learning curve of ms-Tram and DIEP breast reconstructions surgery are important to guide the training of new surgeon. 2. Buried flap post operative monitoring without implantable doppler was seldom studied, a validated…
- Trial name
- NCT05560633
- Testing
- No intervention
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pain Score, Morphine Consumption
Comparison of Efficacy of Regional Blocks in Breast Surgeries.
After Standardized anesthetic induction patients were randomly given regional blocks. Group A recieved erecter spinae plane block \& group B recieved combined serratous anterior and pecto-intercoatal facial plane block.
- Trial name
- NCT07362472
- Testing
- Regional nerve blocks
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Breast Neoplasm
Comparison of FlexHD and Alloderm Outcomes in Breast Reconstructive Surgery
FlexHD and Alloderm are two common products used in breast reconstruction to hold tissue expanders and implants in place. There have been few chart review studies comparing outcomes between the two materials in breast…
- Trial name
- NCT02372305
- Testing
- FlexHD, Alloderm
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
Mastectomy; Lymphedema, Breast Cancer
Examining and Comparing the Temporal Changes and Results of Cosmetic, Quality of Life and Patient Satisfaction Achieved With Immediate and Delayed-immediate Implant-based Breast Reconstruction Procedures and Contralateral Symmetrization Techniques
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Mastectomy; Lymphedema, Breast Cancer, Quality of Life
- Trial name
- NCT04356235
- Testing
- A: expander-silicone implant exchange and contralateral symmetrization with mastopexy and if needed with volume reduction, B: expander-silicone implant exchange with contralateral symmetrization with mastopexy and Ultrapro sling, C: expander-silicone implant exchange and contralateral symmetrization with mastopexy and silicone implant augmentation
- Where
- Hungary
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- National Institute of Oncology, Hungary
Breast Neoplasms
Women Underwent TRAM Surgery: Its Influence on Abdominal Muscle Function and the Effects of Therapeutic Exercises
The unilateral transverse rectus abdominis musculocutaneous (TRAM) flap is a major operation widely used for breast reconstruction.
- Trial name
- NCT04886921
- Testing
- Abdominal muscle training
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Pain, Pain Management
Evaluating The Efficacy Of Pecs II Blockade Compared To Local Anesthetic Infiltration In Controlling Postoperative Pain In Patients Undergoing Oncologic Breast Surgery Under Opioid Free/Sparing Anesthesia.
Breast cancer is the malignant neoplasm with the highest incidence in women in Brazil, with the exception of non-melanoma skin tumors.
- Conditions
- Pain, Pain Management, Anesthesia
- Trial name
- pain (NCT06889870)
- Testing
- Pectoral Nerve Block, Local Anesthesia
- Where
- Brazil
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Mammary Neoplasm, Human, Periodontal Diseases
Cytokine Profiles in Breast Cancer Patients Undergoing Chemotherapy
Aim: This study evaluated the effects of non-surgical periodontal therapy (NSPT) on the cytokine profile and the correlation to clinical parameters of patients undergoing chemotherapy for breast cancer.
- Conditions
- Mammary Neoplasm, Human, Periodontal Diseases, Chemotherapy Effect
- Trial name
- NCT03244943
- Testing
- Non surgical periodontal Treatment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo