Clinical trials: Surgical Condition
Covid19
Clinical Efficiency of Surgical Masks and Filtering Face-piece 2 Masks
Recent results demonstrated an increased risk of COVID-19 infection among healthcare workers (HCW), particularly when access to personal protective equipment (PPE) was inadequate. (ref).
- Trial name
- NCT04823351
- Testing
- Surgical Mask
- Where
- Switzerland
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Gastroesophageal Reflux, Obesity
Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy
The planned research is to analyze the occurrence of gastroesophageal reflux disease (GERD) before and after sleeve gastrectomy (SG).
- Trial name
- SLEEFLUX (NCT05486169)
- Testing
- Sleeve Gastrectomy
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Warmia and Mazury in Olsztyn
Tympanic Membrane Perforation
Comparison Tympanoplasty With Membrane Amniotic and Autologous Fascia
The tympanic membrane separates the middle and the outer ear from each other and consists of three layers. The outer layer is covered with squamous epithelium, a thick basement membrane in the middle and an inner Mucosal layer.
- Trial name
- NCT03569969
- Testing
- device: Tympanoplasty with Membrane Amniotic, Tympanoplasty With Autologous Fascia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mohammad Sadegh Bagheri Baghdasht
Periodontitis (Stage 3), Gremlin-1
Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy
eriodontitis is a complex disease characterized by the inflammation and destruction of the tissues supporting the teeth, and smoking can adversely affect the pathophysiological changes in this process.
- Conditions
- Periodontitis (Stage 3), Gremlin-1, Syndecan 4, Interleukin 1-beta
- Trial name
- NCT06687005
- Testing
- non-surgical periodontal therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tugba Aydin
Total Joint Arthroplasty, Risk Reduction
Arthroplasty and Modifiable Risk Factors
Hip and knee total joint arthroplasty are one of the most frequently performed surgery worldwide. However, prosthetic joint infection remains a devastating complication of them, associated with severe morbidity, increased…
- Conditions
- Total Joint Arthroplasty, Risk Reduction, Surgical Site Infection, Prosthetic-joint Infection
- Trial name
- NCT05399186
- Testing
- Early preoperative assessment and optimization
- Where
- Iceland
- Volunteers
- 1,484 people, healthy volunteers welcome
- Sponsor
- Landspitali University Hospital
Eye Manifestations
Intraoperative OCT Guidance of Intraocular Surgery
The purpose of this study is to investigate the use of optical coherence tomography imaging integrated with an operating microscope (MIOCT) in ophthalmic surgeries.
- Trial name
- MIOCT (NCT01588041)
- Where
- 2 sites in United States
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Duke University
Opioid Use, Pain Postoperative
Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block
This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing…
- Conditions
- Opioid Use, Pain Postoperative, Arthroscopic Knee Surgeries
- Trial name
- NCT06909851
- Testing
- Adductor Canal Block (ACB), Genicular Nerve Block (GNB)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Patient Reported Outcome Measures, Recovery of Function
FIT Study (Functional Outcomes In Trauma Study)
Why? There is not much information in the UK on how well patients who sustain major trauma function afterwards. Major trauma is defined as significant injuries with a calculated 'injury severity score' (ISS) over 15.
- Conditions
- Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation
- Trial name
- NCT04074382
- Testing
- Online Questionnaires, Qualitative Interviews
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Morbid Obesity
Effect of Bariatric Surgery on Bile Acid Homeostasis
The purpose of this study is to evaluate the effect of bariatric surgery in bile acid homeostasis and its interrelationship with the metabolic changes induced by the surgery.
- Trial name
- NCT02366624
- Where
- Chile
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Esophageal Cancer, Nutrition Disorders
Gastrointestinal Nutrient Transit and Enteroendocrine Function After Upper Gastrointestinal Surgery
The incidence of oesophagogastric cancer has increased by 400% since the 1970s in Ireland and the United Kingdom. In addition, refinement of perioperative management and the now widespread use of multimodal protocols for patients…
- Conditions
- Esophageal Cancer, Nutrition Disorders, Appetite Disorders, Dumping Syndrome
- Trial name
- EndoGut (NCT03734627)
- Testing
- Octreotide Acetate, Saline Solution, Paracetamol
- Where
- 2 sites in Ireland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- St. James's Hospital, Ireland
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Non-surgical Retreatment
Effects of Different NiTi Systems on Postoperative Pain and Operation Time in Nonsurgical Endodontic Retreatment
This prospective, randomized, single-center, single-blind clinical trial evaluated the effects of different nickel-titanium retreatment and final shaping systems on postoperative pain and operation time during single-visit…
- Trial name
- NiTi-RETREAT (NCT07783945)
- Testing
- ProTaper Universal Retreatment System, MicroMega REMOVER, ProTaper Next
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Surgical Site Infection
Detection of Staph Colonization in Pre-op Arthroplasty Patients
This study will evaluate which body site(s) provide the best source of possible staph presence in participants undergoing total joint arthroplasty.
- Trial name
- Staph (NCT01648088)
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Anxiety
The Effect of Virtual Reality Glasses Used Before Cesarean Section
The aim of this study is to determine the effect of Virtual Reality Glasses Used Before Cesarean Section on Surgical Fear and Anxiety
- Trial name
- NCT06680141
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Colorectal Cancer
Three-port Versus Conventional Laparoscopic Surgery for Colorectal Cancer
This study is designed to evaluate the short-term and long-term results after three-port laparoscopic surgery for colorectal cancer（TLSC） compared with conventional laparoscopic surgery for colorectal cancer（CLSC）.
- Trial name
- NCT03426514
- Testing
- Three-port Laparoscopic Surgery, Conventional Laparoscopic Surgery
- Where
- China
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Postoperative Complications
Development and Validation of a Morbidity Index for Complications in Minor and Major Abdominal Surgery
The aim is to develop and validate a morbidity index for postoperative complications in patients undergoing visceral surgery.
- Trial name
- NCT00782704
- Where
- Switzerland
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Overactive Bladder, Pelvic Organ Prolapse
The Effect of an Additional Stress Incontinence Procedure on Overactive Bladder During Pelvic Organ Prolapse Repair
Pelvic organ prolapse (POP) is a common condition in women. Approximately 20% of women undergo surgical correction for POP in their lifetime.
- Trial name
- NCT02502838
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Endometriosis, Immunity
Innate Immunity, MIcrobiota and Inovative Treatments in Endometriosis
Endometriosis is a chronic inflammatory, polygenic, and multifactorial disease affecting approximately 10% of women of reproductive age, corresponding to over one million women in France.
- Conditions
- Endometriosis, Immunity, Microbiota
- Trial name
- IMIEndo (NCT07078435)
- Testing
- surgery (any volume) and / or pharmaceuticals treatment initiated or planned or only dynamic observation, in accordance with current clinical guidelines, Blood test, Stool samples
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Infertility, Endometriosis
Comparison Elagolix vs Depot Leuprolide Prior to Frozen Embryo Transfers in Patients With Endometriosis
Patients who have been previously surgically diagnosed with endometriosis and have embryos predicted to be euploid after in vitro fertilization will be divided into 2 groups via randomization.
- Trial name
- NCT04445025
- Testing
- Elagolix 200 MG, Leuprolide Acetate 3.75 MG/ML, Lab work
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colorado Center for Reproductive Medicine
To Determine the Optimal Doses of Adrenaline in Preventing Blood Loos in Participants Undergoing Supraclavicular Flap Surgery
"The Effect Of Subcutaneous Epinephrine Dosage On Blood Loss In Surgical Incision"
Several studies have attempted to calculate the ideal epinephrine concentration for vasoconstriction, however there has been little consensus.
- Trial name
- NCT05670808
- Testing
- Epinephrine injection
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
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