Clinical trials: Surgical Margin
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Prosthesis User, Digitalism
"Clinical Evaluation of Retraction Cord Effectiveness Using Intraoral Scanner
Dental-supported fixed partial dentures (FPDs) have long been a commonly preferred treatment method for the rehabilitation of teeth with excessive substance loss and for addressing existing tooth deficiencies.
- Trial name
- NCT06447389
- Testing
- retraction cordu (SURE-CORD®PLUS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Implants
In the Treatment of Implants With Different Methods; Early Bone Loss and Patient Satisfaction
The aim of this clinical study is to compare two different approaches during dental implant applications. One group of patients in the study received flapless approach which is performed without surgical reflection of soft…
- Trial name
- NCT04459494
- Testing
- Flapless implant surgery., Conventional implant surgery.
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Breast Cancer
Wide Field OCT + AI for Positive Margin Rates in Breast Conservation Surgery.
This is a multi-center, randomized, two-arm study designed to measure the effectiveness of the SELENE system in reducing the number of unaddressed positive margins in breast lumpectomy procedures when used in addition to standard…
- Trial name
- RCT (NCT05113927)
- Testing
- Selene
- Where
- 10 sites in United States
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Perimeter Medical Imaging
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum
Blepharitis
Short-term Effects on Tear Film (Baby Shampoo vs Blephasol)
Lid cleansing is the standard regime that is recommended for the management of blepharitis in the UK and beyond. Whilst many successful commercial preparations exist, and some with clinical evidence, professional guidelines (UK…
- Trial name
- Blepha (NCT04858113)
- Testing
- Blephaclean
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Esophageal Squamous Cell Carcinoma, Positive Circumferential Resection Margin
Adjuvant Radiotherapy for Esophageal Squamous Cell Carcinoma With Positive Circumstantial Resection Margin
The purpose of this study is to determine the efficacy of adjuvant radiotherapy for esophageal squamous cell carcinoma with positive circumstantial resection margin.
- Trial name
- NCT03273647
- Testing
- radiation
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fudan University
Oncology, Breast Cancer
Real-time Diagnosis and Visualization of Tumor Margins in Excised Breast Specimens Using Zenith FLIM Diagnostics
Our investigational team has developed a technology to visualize the operative margins in 'real time,' in other words during the operation while the patient is still on the table.
- Conditions
- Oncology, Breast Cancer, Cancer Diagnosis, Margins of Excision
- Trial name
- NCT04683120
- Testing
- Zenith FLIM Diagnostics
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Laser LabCorp
Gingival Recession, Localized
Gingival Response and Marginal Adaptation of Zirconia Crowns With Two Subgingival Margin Designs
The aim of the study is to evaluate the effect of feather edge finish line and deep chamfer finish line on gingival position, bleeding on probing and marginal adaptation.
- Trial name
- NCT04729569
- Testing
- Feather edge finish line preparation, Deep chamfer finish line preparation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Carcinoma, Basal Cell
Efficiency of Presurgical Basal Cell Carcinoma Margin Mapping
This Interventional Randomised Controlled study is intended to establish that presurgical margin mapping of BCCs with OCT results in a reduction of the number of MMS surgery stages without adversely impacting clinical outcome…
- Trial name
- NCT03420846
- Testing
- OCT Mapped
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Michelson Diagnostics Ltd.
Surgical Site Infection
The Mepilex Cesarean Delivery Trial / MEPIDEL
The goal of this clinical trial is to learn whether a silver-containing foam dressing (Mepilex Border Post-Op Ag) works as well as the standard dressing in preventing surgical site infection after cesarean delivery.
- Trial name
- MEPIDEL (NCT07914569)
- Testing
- Mepilex Border Post-Op Ag, Standard Postoperative Dressing
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Dental Caries
Investigation of the Effect of Deep Margin Elevation Technique on the Clinical Performance of Endocrown Restorations Produced by Computer-Aided Design and Computer-Aided Manufacturing (CAD/CAM) System
The aim of this clinical study is to investigate the impact of the deep margin elevation technique on the clinical performance of CAD/CAM endocrown restorations in deep Class II cavities.
- Trial name
- NCT06222918
- Testing
- Deep Margin Elevation (G-ænial Universal Injectable)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Retroperitoneal Sarcoma, Margin, Tumor-Free
Retroperıtoneal Soft-Tıssue Sarcomas
: Soft Tissue Sarcomas are rare mesenchymal tumors with many subtypes. Clean margin-wide resection is recommended for treatment. The guidelines recommend that sarcoma treatments be carried out in sarcoma centers.
- Trial name
- NCT05044624
- Testing
- retroperitoneal mass excision
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Gingivitis
Influence of the Restorative Cervical Margin Placement on the Supracrestal Tissue Attachment
The aim of the present study is to understand the influence that marginal/subgingival restorations exert on the surrounding periodontal tissues.
- Trial name
- NCT04299347
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Siena
Dental Plaque
Train New Examiners Via Modified Gingival Margin Plaque
The purpose of this study is to train new examiners while testing two commercial products using our standard one-day brushing study regimen by measuring gingival margin plaque index.
- Trial name
- NCT00758563
- Testing
- Fluoride, Triclosan/Fluoride
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
DME, Dental
Clinical Performance of High Viscosity Bioactive Injectable Composite in Deep Marginal Elevation
Using a bioactive resin composite in subgingival Class II cavities can provide enhanced caries resistance by releasing multiple ions, including fluoride.
- Conditions
- DME, Dental, Deep Margin Elevation
- Trial name
- Randomized (NCT06875544)
- Testing
- Beautifil F00, G-aenial Universal Injectable Flowable Composite
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Edentulous Maxilla
4 vs 6 Implants in Totally Edentulous Patient in Maxilla With Ti. Cad-cam Framework
The primary objective of the present study is to evaluate the marginal bone level changes occurring in total edentulous patients treated with six or four implants.
- Trial name
- NCT02405169
- Testing
- 4 vs 6 implant treatment in the maxilla
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institute Franci
Preserve Crestal Bone Level and Gingival Margin Around Dental Implants
A Prospective Clinical and Radiographic Assessment on New Platform-switched Laser Lok Implants
1. To investigate the hard and soft tissue adaptation and maintenance to the Laser-Lok® microchannels permanent abutment/ new Laser-Lok® implant assembly by performing clinical and radiographic evaluations. 2.
- Trial name
- NCT01899131
- Testing
- platform-switch tapered internal implants
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center