Clinical trials: Surgical Margin
Sleep Apnea Syndrome, Obstructive, Drowsiness
Ocular Parameters in Patients With Sleep Apnea
The aim of this study is to assess the ocular parameters of drowsiness in patients with diagnosed Obstructive Sleep Apnea Syndrome through objective methods of ocular imaging and subjective evaluation methods (questionnaire)
- Conditions
- Sleep Apnea Syndrome, Obstructive, Drowsiness, Blinking, Concentration Ability Impaired
- Trial name
- NCT05911737
- Testing
- Short video and Questionnaire
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Complete Placenta Previa
Efficacy Study of Random Placenta Margin Incision to Treat Complete Placenta Previa
The purpose of this study is to assess the efficacy of random placenta margin incision for hemorrhage control during cesarean section of complete placenta previa pregnancies.
- Trial name
- NCT02695069
- Testing
- Random Placenta Margin Incision
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Periodontal Diseases, Dental Plaque
Marginal Biofilm Distribution and Periodontal Response to Supragingival and Juxtagingival Aligner Designs
This prospective, longitudinal, within-person (split-mouth) clinical study evaluates the influence of two clear aligner trimming-line designs on marginal soft-tissue biofilm distribution and periodontal tissue response over a…
- Conditions
- Periodontal Diseases, Dental Plaque, Gingivitis
- Trial name
- BIOFILM-ALIGN (NCT07642037)
- Testing
- Supragingival aligner trimming-line, Juxtagingival festooned aligner trimming-line
- Where
- Romania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- George Emil Palade University of Medicine, Pharmacy, Sciences and Technology of Targu Mures
Gingival Retraction, Gingival Recession
The Impact of Retraction Cords on the Gingival Margin Level.
The purpose of this study is to examine the relationship between placing specific retraction cord for different periods of time and the post-operative gingival margin level in humans.
- Conditions
- Gingival Retraction, Gingival Recession, Periodontal Health
- Trial name
- NCT05949073
- Testing
- Non-impregnated retraction cords/ less than 10 minutes, Non-impregnated retraction cords/ more than 10 minutes, impregnated gingival retraction cord - less than 10 minutes
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Jordan
Edentulous Maxilla
4 vs 6 Implants in Totally Edentulous Patient in Maxilla With Ti. Cad-cam Framework
The primary objective of the present study is to evaluate the marginal bone level changes occurring in total edentulous patients treated with six or four implants.
- Trial name
- NCT02405169
- Testing
- 4 vs 6 implant treatment in the maxilla
- Where
- Italy
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Institute Franci
Dental Caries Secondary to Acquired Defects of Tooth Structure
10-years Clinical Trial of Sealed of Margin Failures
Assess the effectiveness of sealing localized marginal defects of amalgam restorations that were initially scheduled for replacement of restorations.
- Trial name
- Sealant (NCT02075801)
- Testing
- Sealing of amalgam margin defects
- Where
- Chile
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Chile
Irregular; Contour of Cornea, Keratoconus
Scleral Versus Corneal RGP Contact Lenses in Irregular Cornea Disorders
The most common causes for irregular cornea (IC) in hospital contact lens practice are Keratoconus (KC) and related cornea thinning disorders.
- Conditions
- Irregular; Contour of Cornea, Keratoconus, Pellucid Marginal Corneal Degeneration, Injury of Cornea
- Trial name
- NCT02444923
- Testing
- Scleral rigid gas permeable contact lenses (SRGPcl) (Zenlens™), Corneal Rigid gas Permeable contact lenses (CRGPcl) (Rose K2)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London South Bank University
Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase
Clinical Assessment of UV Photofunctionalization on Stability and Osseointegration of Early Loaded Implants
The goal of this clinical trial is to learn if UV light treatment (photo functionalization) works to help dental implants heal faster and become stable enough for early use in adults missing teeth in the lower back jaw.
- Conditions
- Evaluating the Clinical Efficacy of Applying Ultraviolet Photofunctionalization (UV phF) to Standard Titanium Implants Immediately Before Surgery, Monitoring Early Implant Stability and Osseointegration During the Critical Initial Healing Phase, Determining the Feasibility and Success Rate of an Accelerated "Early Loading" Protocol, Assessing the Survival Rate of the Implants, Along With the Peri-implant Soft Tissue Response and Marginal Bone Preservation
- Trial name
- UV (NCT07868744)
- Testing
- UV-photofunctionalized titanium dental implants
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Thick Gingival Margin to Tooth Restoration
Aesthetic Outcomes of Single Tooth Implant Using Metal Ceramic Restorations With Either Zirconia or Titanium Abutments
Different studies have proposed the use of zirconia abutments to improve the aesthetic outcomes in the anterior sextant, however the results have been inconclusive.
- Trial name
- NCT02315794
- Testing
- SPI®ART, SPI®EASY
- Where
- 2 sites in Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Firenze and Siena, Napoli, Italy
Prostate Cancer Adenocarcinoma, Erectile Dysfunction Following Radical Prostatectomy
Use of Indocyanine Green in Robotic Prostate Surgeries
Imaging of the vascular nerve bundle using Indocyanine Green
- Trial name
- NCT05960149
- Testing
- using Indocyanine Green, Nerve-sparing robot-assisted laparoscopic radical prostatectomy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ankara University
Achalasia, Gastric Fistula
Outcome Analysis of POEM and Endoluminal Therapies
Evaluation of current and newly developed endoluminal therapies in the management of Upper and Lower GI conditions.
- Conditions
- Achalasia, Gastric Fistula, Weight Gain After Primary Weight Loss Surgery, Marginal Ulcer
- Trial name
- NCT03123835
- Testing
- Endoscopic Intervention
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Carcinoma, Basal Cell
Efficiency of Presurgical Basal Cell Carcinoma Margin Mapping
This Interventional Randomised Controlled study is intended to establish that presurgical margin mapping of BCCs with OCT results in a reduction of the number of MMS surgery stages without adversely impacting clinical outcome…
- Trial name
- NCT03420846
- Testing
- OCT Mapped
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Michelson Diagnostics Ltd.
Tumor, Brain, Tumor, Breast
Microscopy Imaging of Whole-mount Stained Human Tissues
The goal of this clinical trial is to develop an imaging platform for intraoperative tumor margin delineation in 250 cases of tumor-suffered patients.
- Conditions
- Tumor, Brain, Tumor, Breast, Tumor Skin
- Trial name
- NCT05689112
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Different Surgical Techniques in Dental Implant Surgery
Effect of Different Drilling Techniques on Primary Stability and Marginal Bone Loss of Extra Short Implants
Our aim in this study is to compare the effects of low-speed drilling surgery technique without irrigation and conventional implant surgery technique with irrigation on extra short implants.
- Trial name
- NCT06234566
- Testing
- Conventional dental implant surgery, Low Speed Drilling Without Irrigation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Deep Margin Elevation, Pulpal and Periodontal Health
Impact of DME on Pulpal and Periodontal Health at Varying Gingival Seat Level
The classical idea was to keep the biologic width untouched in order to maintain periodontal health but the newer case reports have given a new dimension to this concept, stating that a limited extension into STA can be used as…
- Trial name
- NCT07169305
- Testing
- Deep Margin Elevation
- Where
- India
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Endodontically Treated Teeth
Deep Margin Elevation Vs Crown Lengthening
The present clinical trial will be conducted to reject or accept the null hypothesis that in endodontically treated posterior teeth with deeply located proximal margins, will the Deep Margin Elevation will have better results…
- Trial name
- NCT05381298
- Testing
- Deep Margin Elevation using resin composite, Surgical Crown Lengthening
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Contact Lens Discomfort
The Effect of Eyelid Margin Debridement on Contact Lens Discomfort
In this study, clinical variables related to eyelids that potentially have an effect on contact lens discomfort will be investigated such as eyelid signs and secretions, eyelid sensitivity, eyelid microbiome, Demodex infestation…
- Trial name
- NCT03311204
- Testing
- BlephEx, Lid Hygenix
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of New South Wales
BCC - Basal Cell Carcinoma, BCC
CellFX Treat & Resect Low-Risk BCC Feasibility Study
This prospective, multicenter, study is designed to evaluate the safety and effectiveness of the CellFX System in adults subjects with low-risk basal cell carcinoma (superficial and nodular) for complete histological clearance of…
- Conditions
- BCC - Basal Cell Carcinoma, BCC, Excision Margin
- Trial name
- NCT04918381
- Testing
- CellFX System
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pulse Biosciences, Inc.
Blepharitis
Lipids of the Human Tear Film and Their Effect on Tear Stability
This prospective, randomized, comparative clinical trial evaluates the effect of either oral doxycycline, oral essential fatty acid, or topical azithromycin to modify the secretions of the meibomian gland in subjects with…
- Trial name
- NCT00803452
- Testing
- doxycycline, azithromycin
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Surgical Site Infection
The Mepilex Cesarean Delivery Trial / MEPIDEL
The goal of this clinical trial is to learn whether a silver-containing foam dressing (Mepilex Border Post-Op Ag) works as well as the standard dressing in preventing surgical site infection after cesarean delivery.
- Trial name
- MEPIDEL (NCT07914569)
- Testing
- Mepilex Border Post-Op Ag, Standard Postoperative Dressing
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center