Clinical trials: Surgical Oncology
Colon Cancer, Rectal Cancer
Pilot Study Evaluating the Efficacy of AlloMEM After Loop Ileostomy
The objective of this study is to investigate whether the use of Human Peritoneal Membrane (HPM) in a temporary loop ileostomy is beneficial to patients.
- Trial name
- AlloMem (NCT01113736)
- Testing
- AlloMEM™
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Given Indication for Gastroesophageal Cancer Surgery
Diagnostic Value of C-reactive Protein for Detection of Postoperative Inflammatory Complications After Gastroesophageal Cancer Surgery
Although widely used, there is a lack of evidence concerning diagnostic value of C-reactive protein (CRP) in the postoperative course.
- Trial name
- NCT01249534
- Testing
- gastroesophageal cancer surgery
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Cantonal Hospital of St. Gallen
Brain Metastases
Stereotactic Radiotherapy of Resection Cavity For Single Brain Metastasis Versus Whole-Brain Radiotherapy After Resection
Adjuvant whole-brain radiation therapy (WBRT) after resection of single brain metastasis is considered as a standard associated with side effects leading to decreased neurocognitive function.
- Trial name
- NCT01535209
- Testing
- stereotactic body radiotherapy (SBRT), Whole-Brain Radiotherapy (WBRT)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Colorectal Cancer, Inflammatory Bowel Diseases
Optimizing Postoperative Nutrition in Colorectal Surgery
Major surgical operations of the gastrointestinal tract, such as colorectal resections due to several diseases, lead to significant burden on the human body, which is expressed during the first postoperative hours with an intense…
- Conditions
- Colorectal Cancer, Inflammatory Bowel Diseases, Bowel Ischemia, Malnutrition
- Trial name
- OPTI-NUTRICS (NCT06737211)
- Testing
- Peripheral Parenteral Nutrition
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Breast Cancer
Use of Continuous Wound Infusion of Bupivacaine for Analgesia Following Axillary Clearance Surgery
Axillary clearance forms part of the surgical armamentarium for the treatment of breast cancer. Although the introduction of sentinel lymph node mapping and dissection has allowed for the decreased use of axillary clearance, it…
- Trial name
- NCT01314144
- Testing
- Bupivacaine
- Where
- Ireland
- Volunteers
- 42 people
- Sponsor
- Cork University Hospital
Cancer Survivor, Prostate Carcinoma
Long-Term Follow-Up in Patients With Prostate Cancer After Surgery
This clinical trial studies how well a long-term follow-up works in patients with prostate cancer after surgery. Long-term follow-up data may serve as a resource to help ask clinical questions, describe health-related quality of…
- Trial name
- NCT03035500
- Testing
- Educational Intervention, Laboratory Biomarker Analysis, Long-term Follow-up
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- City of Hope Medical Center
Pancreatic Fistula
Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.
Main goal of this study is to evaluate the blood flow in a post resection pancreatic remnant after pancreaticoduodenectomy with use of indocyanine green fluorescence.
- Trial name
- NCT06198400
- Testing
- Perioperative assessment of the perfusion of post-resection pancreatic remnant using indocyanine green-VerDye
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Charles University, Czech Republic
Gynecologic Cancer, Enhanced Recovery After Surgery
Prehabilitation Plus ERAS Versus ERAS in Gynecologic Oncology: a Randomized Clinical Trial
Prospective, interventionist, controlled and randomized study to test the effectiveness of a multimodal prehabilitation protocol in patients who will undergo gynecological surgery.
- Trial name
- PROPER (NCT04596800)
- Testing
- Prehabilitation Program + Enhanced Recovery After Surgery, Enhanced Recovery After Surgery
- Where
- Brazil
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Brain Tumor, Brain Cancer
A Study to Measure the Effect of Brain Stimulation on Hand Strength and Function in Patients With Brain Tumors
The neurosurgical standard of care for treating a patient with a tumor invading hand primary motor cortex (M1) includes performing a craniotomy with intraoperative direct electrical stimulation (DES) mapping and to resect as much…
- Conditions
- Brain Tumor, Brain Cancer, Motor Cortex; Lesion
- Trial name
- NCT05023434
- Testing
- Intraoperative Brain Simulation - Alternate Stimulation Parameters
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Ovarian Cancer
Fenretinide Followed by Surgery Compared With Surgery Alone in Preventing Ovarian Cancer in Patients at Increased Risk
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development of cancer. It is not yet known whether fenretinide given before surgery is more effective in preventing ovarian cancer than surgery…
- Trial name
- NCT00017134
- Testing
- fenretinide, conventional surgery
- Where
- 35 sites in United States
- Volunteers
- 71 people
- Sponsor
- Gynecologic Oncology Group
Early Stage Breast Carcinoma
Sentinel Node Vs Observation After Axillary Ultra-souND
The hypothesis of this trial are that: avoiding axillary surgery does not worsen the outcome of patients with small breast cancer the absence of the pathological information on the risk of recurrence given by nodal status is not…
- Trial name
- SOUND (NCT02167490)
- Testing
- Arm 1: sentinel node biopsy
- Where
- 18 sites in Chile, Italy and 2 more
- Volunteers
- 1,560 people
- Sponsor
- European Institute of Oncology
Lung Neoplasms
Effects of Early Mobilization and Feeding After Lobectomy
This randomized controlled study evaluates the effects of early mobilization and early oral feeding, two components of the Enhanced Recovery After Surgery (ERAS) protocol, on postoperative outcomes in adult patients with lung…
- Trial name
- NCT07749950
- Testing
- Early Mobilization, Early Oral Feeding, Standard Postoperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ege University
Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor
Etoposide, Carboplatin, and Bleomycin in Treating Young Patients Undergoing Surgery For Malignant Germ Cell Tumors
RATIONALE: Drugs used in chemotherapy, such as etoposide, carboplatin, and bleomycin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Brain and Central Nervous System Tumors, Childhood Germ Cell Tumor, Extragonadal Germ Cell Tumor, Ovarian Cancer
- Trial name
- NCT00276718
- Testing
- bleomycin sulfate, carboplatin, etoposide
- Where
- 22 sites in Ireland, United Kingdom
- Volunteers
- 100 people
- Sponsor
- Children's Cancer and Leukaemia Group
Gastric Cancer
A Study of Capecitabine (Xeloda) in Combination Chemotherapy Versus Surgery Alone in Participants With Gastric Cancer
This study will compare capecitabine/oxaliplatin as adjuvant chemotherapy versus observation alone in chemotherapy-naive participants who have undergone potentially curative resection for gastric cancer.
- Trial name
- NCT02560974
- Testing
- Capecitabine, Oxaliplatin
- Where
- 36 sites in China, South Korea and 1 more
- Volunteers
- 1,035 people
- Sponsor
- Hoffmann-La Roche
Breast Cancer, Anxiety
AR Health Education Video for Postoperative Breast Cancer Patients
Breast cancer surgery patients may experience anxiety and depression before and after surgery. Health education can help patients understand the surgical process and postoperative care, but traditional education may not always be…
- Conditions
- Breast Cancer, Anxiety, Depression
- Trial name
- AR-BCS (NCT07604389)
- Testing
- Augmented Reality Health Education Video, Routine Health Education
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Elderly Patients, Solid Organ Cancer
Epidural Anesthesia and Long-term Outcomes in Elderly Patients After Surgery
Surgical resection is one of the most important treatments for solid organ cancer. Whereas cancer recurrence and/or metastasis are the major reasons of treatment failure.
- Conditions
- Elderly Patients, Solid Organ Cancer, Surgical Resection, Epidural Anesthesia
- Trial name
- NCT03335826
- Testing
- Combined epidural-general anesthesia, General anesthesia
- Where
- 5 sites in China
- Volunteers
- 1,802 people
- Sponsor
- Peking University First Hospital
Nursing, Gynecological Cancers
Effects of a Self-Regulation Based E-MOTE Program Delivered Via an AI-Assisted Robot and Supported by Mobile Platforms for Newly Diagnosed Gynecologic Cancer Patients
To evaluate the effectiveness of the E-MOTE Emotional Care Program, delivered through the Kebbi robot and the LINE Official Account, for patients newly diagnosed with gynecologic cancer undergoing surgery.
- Conditions
- Nursing, Gynecological Cancers, Psycho-Oncology
- Trial name
- NCT07745478
- Testing
- E-MOTE group
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Colorectal Cancer
Clinical Application of Carbon Nanoparticles in Lymph Node Tracing and Surgery Guiding of Colorectal Cancer
This trial aims to clarify the relationship between carbon nanoparticles labeled lymph nodes and lymph node metastasis in different lymph node regions of colorectal cancer, and to clarify the application value of carbon…
- Trial name
- CNP-CRC (NCT06783985)
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Sir Run Run Shaw Hospital
Colorectal Cancer, Quality of Life
Follow-up After Surgery for Colorectal Cancer
The currently developed implementation study aims to evaluate if a patient-led home-based follow-up approach is successful, improves quality of life, reduces anxiety and lessens fear of cancer recurrence during the years after…
- Trial name
- FUTURE-primary (NCT05656326)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Erasmus Medical Center
Opioid Use, Auriculotherapy
Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
The NSS-2 BRIDGE® device (NSS stands for Neuro-Stimulation System) is a disposable device that stimulates the branches of cranial nerves and of the superficial cervical plexus innervating the ear.
- Conditions
- Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain
- Trial name
- NCT05506878
- Testing
- NSS-2 BRIDGE
- Where
- 4 sites in United States
- Volunteers
- 286 people
- Sponsor
- Jacques E. Chelly
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.