Clinical trials: Surgical Wound Healing
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Ventral Hernia
Repair of Large Incisional Hernias - To Drain or Not to Drain Randomised Clinical Trial
The aim of this study was to perform a randomised clinical trial comparing the use of closed-suction tubular drains and progressive tension sutures in individuals with large incisional hernias subjected to onlay mesh repair to…
- Trial name
- NCT02163460
- Testing
- Drain, Progressive Tension Sutures
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Oeste do Paraná
Hydrocele, Inguinal Hernia
Study of Transverse Abdominis Plane (TAP) Block in Children Undergoing Hydrocelectomy and/or Hernia Repair Surgery
Study measures the difference in pain after hernia \&/or hydrocele repair based on site of local anesthesia injection.
- Trial name
- TAP (NCT01698268)
- Testing
- TAP block, Local Infiltration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Kaveh Aslani, MD
Rotator Cuff Tear
The Impact of Psychological Factors on the Outcome of Surgical Repair for Rotator Cuff
The proposed study will be a multi-centre, prospective, observational cohort to determine if psychological well-being has an impact on the outcome of surgical repair for rotator cuff tears.
- Trial name
- IMPROVE (NCT03018210)
- Testing
- Surgical repair of the rotator cuff
- Where
- 5 sites in Canada
- Volunteers
- 267 people
- Sponsor
- Unity Health Toronto
Symptomatic Haemorrhoidal Disease
Recto Anal Repair or Milligan Morgans Operation of Grade 3 and 4 Symptomatic Haemorrhoidal Disease
The purpose of this study is to compare a new mini invasive surgical procedure (Recto Anal Repair) to the traditional Milligan-Morgan procedure in patients suffering from severe piles.
- Trial name
- NCT01038141
- Testing
- Surgery for advanced haemorrhoidal disease
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- University Hospital, Akershus
Mitral Valve Regurgitation
Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study
Evaluation of the technical feasibility and safety of the Mitral Adjustable Annuloplasty Ring.
- Trial name
- MAARS (NCT00554151)
- Testing
- Adjustable Annuloplasty Ring
- Where
- 5 sites in Germany, Italy and 1 more
- Volunteers
- 55 people
- Sponsor
- Abbott Medical Devices
Post Operative Pain, Inguinal Hernia
Comparison of Two Different Analgesic Regional Block Techniques in Pediatric Patients Undergoing a Hernia Repair
Lower abdominal operations; especially inguinal hernia repairs are one of the most frequently performed operations in the daily practice of pediatric surgeries.Regional anesthesia techniques are frequently and effectively used…
- Trial name
- NCT05896072
- Testing
- Erector Spinae Plane Block, Caudal Block
- Where
- 7 sites in Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Abant Izzet Baysal University
Adenocarcinoma - GEJ, Gastric Adenocarcinoma
DEWI: Watch-and-Wait With Dostarlimab in Localized dMMR/MSI-H Gastric/GEJ Adenocarcinoma Phase II Study
This phase II study evaluates dostarlimab followed by a watch-and-wait strategy in patients with localized dMMR/MSI-H gastric or gastroesophageal junction (GEJ) adenocarcinoma.
- Trial name
- DEWI (NCT06059495)
- Testing
- Dostarlimab
- Where
- 18 sites in France, Italy
- Volunteers
- 89 people
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Cleft Lip, Cleft Palate
Cleft Palate Surgery and Speech Development
Compare the outcome of two primary surgeries techniques (von Langenbeck and Furlow double z-plasty) performed on children with cleft lip/palate to determine if one results in significantly better velopharyngeal competency for…
- Trial name
- NCT00004639
- Testing
- Furlow double z-plasty palatoplasty palate repair, Von Langenbeck palatoplasty palate repair
- Where
- 2 sites in United States, Brazil
- Volunteers
- 475 people
- Sponsor
- University of Florida
Hernia Inguinal
Pilot Study on the Effectiveness of a TAP-block for Inguinal Hernia Repair
An prospective double blinded randomised trial,whether the use of an perioperative echoguided unilateral TAP block has an superior effect on postoperative pain after open hernia inguinal repair compared to wound infiltration with…
- Trial name
- NCT01793571
- Testing
- TAP block
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dijklander Ziekenhuis
Surgical Wound, Knee Disease
Standard Dressing Versus Moist Dressing in the Course of the Postoperative Wound in Patients With Knee Prosthesis
The aim of the study is: to evaluate the efficacy of two post-operative dressings in the management of the surgical wounds in patients who received a knee prosthesis
- Trial name
- APOSIT-PTG (NCT04422119)
- Testing
- Multi-Foam dressing, Usual care
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Germans Trias i Pujol Hospital
Tendon Injury - Hand
Wide Awake Surgery for Tendon Repair in Hand Trauma
Wide awake surgery for tendon repair in hand trauma To compare the functional outecomes in terms of active range of motion for tendon repair surgeries performed under wide awake anaesthesia versus general anaesthesia.
- Trial name
- NCT04618107
- Testing
- Wide awake surgery, General anaesthesia
- Where
- Pakistan
- Volunteers
- 130 people
- Sponsor
- Dow University of Health Sciences
Inguinal Hernia, Surgery
Laparscopic Inguinal Hernia Repair - Does the Choice of Self-fixated Mesh Matter?
Self-fixed mesh and postoperative pain after laparoscopic inguinal hernia surgery, a randomized clinical trial
- Trial name
- NCT05091853
- Testing
- Adhesix mesh
- Where
- Finland
- Volunteers
- 174 people
- Sponsor
- Helsinki University Central Hospital
Rotator Cuff Tear
Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement
Rotator cuff tears result in shoulder joint pain and movement disorders, affecting patients' daily lives. The incidence rate rises with age and can be as high as 54% among people over 60 years old.
- Trial name
- NCT06766630
- Testing
- Silk fibroin surgical mesh
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Weiliang Shen, Ph.D., M.D.
Anal Fistula
Ligation of Intersphincteric Fistula Tract (LIFT) Procedure Versus Use of an Anal Fistula Plug for Anal Fistula Repair
Anal fistulae are a difficult problem to treat. The optimal treatment for fistula involving the anal sphincter is unclear. Two standardly used methods of treatment are the ligation of intersphincteric fistula track (LIFT)…
- Trial name
- LIFT vs PLUG (NCT00830661)
- Testing
- Ligation of intersphincteric fistula track procedure, anal fistula plug
- Where
- 4 sites in United States, Canada
- Volunteers
- 124 people
- Sponsor
- Colon and Rectal Surgery Associates, Ltd.
Minimal Invasive Cardiac Surgery, Minimal Invasive Cardiac Surgery Mitral Valve Surgery
Serratus Plane Block After Minimally Invasive Mitral Valve Repair
Patients undergoing minimally invasive mitral valve reconstruction via small thoracotomy are randomized into two groups. The intervention group receives serratus anterior plane block after minimally invasive mitral-valve…
- Conditions
- Minimal Invasive Cardiac Surgery, Minimal Invasive Cardiac Surgery Mitral Valve Surgery, Serratus Anterior Plane Block
- Trial name
- NCT05648266
- Testing
- Continous SAPB (Ropivacain), institutional standard of care pain medication protocol
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Corneal Diseases
Using in Vivo Confocal Microscope to Evaluate the Corneal Wound Healing After Various Ocular Surgeries
Although epi-keratome laser-assisted in situ keratomileusis (Epi-LASIK), penetrating keratoplasty and pars plana vitrectomy with corneal epithelial debridement for diabetic retinopathy are surgeries commonly performed, the…
- Trial name
- NCT00491439
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Blood Loss, Surgical
Efficacy Study of Recombinant Protein (Ecallantide) to Reduce Blood Loss During Primary Coronary Bypass Grafting or Valve Repair/Replacement
The primary objective of this study was to assess the efficacy and safety of 2 dose levels of ecallantide versus placebo in reducing blood loss following cardiopulmonary bypass (CPB), as measured by chest tube drainage during the…
- Trial name
- NCT00448864
- Testing
- Ecallantide
- Where
- 15 sites in United States
- Volunteers
- 75 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Hernia, Inguinal
PHS, Lichtenstein Mesh, and PerFixPlug for Primary Inguinal Hernia Repair - 3 Years Results
Three different techniques for the surgical repair of groin hernias are compared. Focus has been set on operation times, time to full return of functional abilities like walking in stairs etc, and if any technique has more…
- Trial name
- BOOP (NCT00580177)
- Testing
- Lichtenstein mesh, PerFix Plug®, Prolene® Hernia System
- Where
- Sweden
- Volunteers
- 472 people
- Sponsor
- Göteborg University
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
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