Clinical trials: Suspected Sarcoidosis
Pulmonary Sarcoidosis
Breath Analysis in Patients With Suspected Sarcoidosis: The VOCs-IS Study
Sarcoidosis is a chronic condition which predominantly affects the lungs and lymph glands within the chest, however, may affect any organ within the body.
- Trial name
- NCT04318392
- Testing
- Breath Analysis, Pulmonary Function Tests, Blood sampling and storage for genetic analysis
- Where
- 2 sites in United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Mediastinal Lymph Node Enlargement, Sarcoidosis
Bronchoscopic Sampling Techniques in Sarcoidosis
The development of endobronchial ultrasound (EBUS) and EBUS-guided transbronchial needle aspiration (EBUS-TBNA) has improved the safety and diagnostic accuracy of the mediastinal lymph node (MLN) sampling.
- Conditions
- Mediastinal Lymph Node Enlargement, Sarcoidosis, Tuberculosis, Lymphomas
- Trial name
- NCT01836822
- Testing
- EBUS guided transbronchial forceps biopsy (EBUS-TBFB), EBUS guided transbronchial needle aspiration (EBUS-TBNA), large bore (19G) histologic needle biopsy of the mediastinal lymph nodes
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Warsaw
Suspected Sarcoidosis
Comparing Menghini-type Needle and Franseen-type Needle in EBUS-TBNA for Sarcoidosis
This randomized pilot clinical trial aims to examine whether sample collection with Franseen-type needles are effective for the diagnosis of sarcoidosis, as defined by improved sample quality for pathological diagnosis compared…
- Trial name
- NCT06220526
- Testing
- endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- University Health Network, Toronto
Cardiac Sarcoidosis
PET Imaging in Patients With Suspected Cardiac Sarcoidosis
Gallium-68 DOTATATE is a radioactive tracer, a type of imaging drug that is labeled with a radioactive tag and injected into the body, which is approved by the U.S. Food and Drug Administration (FDA) to diagnose certain tumors.
- Trial name
- NCT03746847
- Testing
- Gallium-68 DOTATATE
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Sarcoidosis
An RCT of 19G EBUS-TBNA Needle in Suspected Sarcoidosis
Sarcoidosis is an idiopathic disorder characterized by granulomatous inflammation involving various organ systems. The lung and mediastinal lymph nodes are the most commonly involved structures in sarcoidosis.
- Trial name
- GUESS (NCT04770948)
- Testing
- 19 gauge needle, 22 gauge needle
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Endobronchial Mucosal Pathology in Pulmonary Sarcoidosis
Endobronchial Mucosal Biopsy in Patients With Suspected Pulmonary Sarcoidosis
This prospective interventional study was done between May and September 2020. We included 20 patients from the chest department, Alexandria Main University Hospital (AMUH) with the inclusion criteria of having suspected…
- Trial name
- NCT04904939
- Testing
- Bronchoscopic mucosal biopsy
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Sarcoidosis
A Study Evaluating the Diagnostic Yield and Safety of the ProCore vs Conventional EBUS-TBNA Needle in Subjects With Suspected Sarcoidosis
This study evaluates the yield and safety of two different needles for performing endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) in patients with sarcoidosis.
- Trial name
- NCT03656003
- Testing
- Procore biopsy needle, Conventional biopsy needle
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Cardiac Sarcoidosis, Infective Endocarditis
A Prospective Diagnostic Trial of Al[¹⁸F]F-NOTA-folate PET in Patients With Suspected Cardiac Sarcoidosis and Infective Endocarditis
The goal of this prospective diagnostic study is to evaluate the imaging characteristics, diagnostic performance, radiation dosimetry, and safety of Al[¹⁸F]F-NOTA-folate PET imaging in patients with suspected cardiac sarcoidosis…
- Trial name
- FOL-CARD (NCT07814222)
- Testing
- Al[¹⁸F]F-NOTA-folate PET imaging, [15O]water PET imaging, Echocardiography
- Where
- Finland
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Sarcoidosis Lung, Pulmonary Sarcoidosis
Comparative Diagnostic Yield of Endobronchial Cryo Biopsy vs Forceps Biopsy in Patients With Suspected Sarcoidosis
Sarcoidosis is a multi-systemic granulomatous disease of unknown cause that is characterized by the formation of non-caseous epithelioid cell granulomas.
- Trial name
- CREBS (NCT06853834)
- Testing
- Cryobiopsy with liquid nitrogen, Endobronchial Forceps Biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Sarcoidosis
Somatostatin Receptor Imaging in Patients With Suspected Cardiac Sarcoidosis
The purpose of this research study to find out if a drug called OctreoScan or DOTATATE can help doctors diagnose people with cardiac sarcoidosis better. OctreoScan and DOTATATE are both approved by the U.S.
- Trial name
- NCT02546388
- Testing
- Indium-111 Pentreotide, Gallium-68 DOTATATE
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Marcelo F. Di Carli, MD, FACC
Sarcoidosis, Cardiac Sarcoidosis
Routine Cardiac Screening in Sarcoidosis Patients
This protocol is an unblended randomized screening trial will have consecutive patients with no suggestion of cardiac sarcoidosis according to usual screening enroll in an enhanced screening protocol.
- Conditions
- Sarcoidosis, Cardiac Sarcoidosis, Boeck's Disease, Besnier-Boeck Disease
- Trial name
- PAPLAND (NCT03902223)
- Testing
- Enhanced Screening Protocol for Cardiac Sarcoidosis., Routine Screening for Suspected Cardiac Sarcoidosis
- Where
- 12 sites in United States, Netherlands and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Foundation for Sarcoidosis Research
Sarcoidosis, Diabetes Mellitus
A Suspected Association Between Sarcoidosis and Development of Diabetes Mellitus
The purpose of the study is to determine the characteristics of patients with diabetes and sarcoidosis and to compare them with those of patients with diabetes and no sarcoidosis.
- Trial name
- NCT03805633
- Testing
- Venous blood sample, Ultrasound of pancreas
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sarcoidosis, Pulmonary
An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis
In the diagnosis of patients with sarcoidosis, there is paucity of literature on the diagnostic yield of the endobronchial biopsies obtained with narrow band imaging (NBI) bronchoscopy.
- Trial name
- NABS (NCT05311150)
- Testing
- Narrow band imaging bronchoscopy guided endobronchial biopsy, White light bronchscopy guided endobronchial biopsy
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh