Clinical trials: Symptoms, Behavioral
Suicide, Attempted
DBT Skills Groups for Veterans at High Risk for Suicide Attempt
Veteran suicide death is a national crisis. Risk factors include emotion dysregulation, which occurs across mental health disorders.
- Trial name
- NCT05000749
- Testing
- DBT-SG, VHA treatment as usual
- Where
- 5 sites in United States
- Volunteers
- 156 people
- Sponsor
- VA Office of Research and Development
Chronic Obstructive Pulmonary Disease, Depression
Investigating the Impact of Mode of Administration on Item Response
The Patient-Reported Outcomes Measurement Information System (PROMIS) is an NIH Roadmap initiative to develop a computerized system measuring patient-reported outcomes in respondents with a wide range of chronic diseases and…
- Conditions
- Chronic Obstructive Pulmonary Disease, Depression, Rheumatoid Arthritis
- Trial name
- NCT00783991
- Where
- 2 sites in United States
- Volunteers
- 800 people
- Sponsor
- Stony Brook University
Insomnia, Cancer
The Sleepio After Cancer Study
This study will recruit women over the age of 18 with a current or prior cancer diagnosis who have clinical insomnia. This study will examine the efficacy of digital cognitive behavioural therapy for insomnia (dCBT-I) compared to…
- Trial name
- SACS (NCT05816460)
- Testing
- Digital Cognitive Behavioural Therapy for Insomnia (dCBT-I), Sleep Hygiene Education (SHE)
- Where
- Ireland
- Volunteers
- 308 people
- Sponsor
- University College Dublin
Disordered Eating Behaviors, Disordered Eating
Can a Single-session Intervention Decrease Risk for Mental Health Symptoms in Young Adults? A Preliminary Investigation of Feasibility and Acceptability
This project has two primary aims: 1) to develop a single session intervention to understand different forms of self-evaluation with input from young adults, and 2) to examine whether a single session can improve the ways in…
- Trial name
- NCT07149324
- Testing
- Single Session for Overevaluation
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Chloe White
Lung Cancer, Medication Adherence
Implementation Strategies for Monitoring Adherence in Real Time
The objective of this project is to identify effective strategies to help patients with lung cancer manage side effects and achieve optimal adherence to oral targeted therapies.
- Conditions
- Lung Cancer, Medication Adherence, Symptoms and Signs
- Trial name
- iSMART (NCT04347161)
- Testing
- Conversational Agent/Chatbot, Usual Care
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Stuttering, Adult
Information Processing Biases in Adults Who Stutter
The goal of this clinical trial is to examine whether stuttering is associated with a tendency to attend more quickly or for longer durations to threat-related information in the environment (threat-related attention bias).
- Trial name
- NCT06422442
- Testing
- Threat-related stimulus exposure
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Mild Cognitive Impairment, Dementia
Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD
The purpose of this study is to test the usefulness and the effect of Smart Virtual Reminiscence (SVR) therapy intervention on the Behavioral and Psychological Symptoms of Dementia (BPSD) of patients with Alzheimer's Disease and…
- Conditions
- Mild Cognitive Impairment, Dementia, BPSD, BPSD (Behavioral and Psychological Symptoms of Dementia)
- Trial name
- SVR (NCT07499570)
- Testing
- Smart Virtual Reminiscence Therapy, Music Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Indiana University
Stress, Psychological, Compassion Fatigue
Achieving Resilience in Acute Care Nurses (ARISE).
Nurses are exposed to myriad stressors, both in the workplace and in their everyday lives, which can lead to adverse personal and professional outcomes.
- Trial name
- NCT03017469
- Testing
- ARISE
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- Unity Health Toronto
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Pain Management, Satisfaction
Effectiveness of Game-Based Learning in Pain Management Education for Nursing Students
Aim: To evaluate the effectiveness of game-based learning on undergraduate nursing students' pain management knowledge, learning motivation, and educational satisfaction. Background: Pain management is a core nursing competency.
- Conditions
- Pain Management, Satisfaction, Motivation, Knowledge
- Trial name
- NCT07736118
- Testing
- game-based learning
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- TC Erciyes University
Rectal Cancer, Gender
Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study
Objective: To investigate gender-based differences in outcomes following robotic surgery for rectal cancer. Methods: A retrospective study was conducted on 155 patients (82 males, 73 females) who underwent robotic surgery for…
- Conditions
- Rectal Cancer, Gender, Complication,Postoperative, Surgery-Complications
- Trial name
- NCT06391060
- Testing
- Impact of Gender on Davinci rectal surgery
- Where
- China
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Daorong Wang
Depression, Anxiety
Community Intervention to Improve Depressive Symptoms Among Older Adults (VIDACTIVA)
The goal of this pilot trial is to test how feasible is to conduct a large clinical trial that evaluate both implementation and effectiveness outcomes of a community-based interventions for older adults with depression in…
- Trial name
- VIDACTIVA1 (NCT06065020)
- Testing
- VIDACTIVA sessions, Standard Care
- Where
- Peru
- Volunteers
- 72 people
- Sponsor
- Universidad de San Martín de Porres
Cardiovascular Diseases, Hypercholesterolemia
Plant Sterols on Cardiovascular Markers, Microbiota and Sterol Metabolism (Cardiofoodsterol)
Potential cholesterol-lowering effect of a regular intake of a plant sterol (PS)-containing food supplement, in overweight/obese type 1 or 2, normoglycemic/pre-diabetic, with LDL-cholesterol values > 115 mg/dl and not…
- Conditions
- Cardiovascular Diseases, Hypercholesterolemia, Prediabetic State, Overweight and Obesity
- Trial name
- NCT06481020
- Testing
- Plant sterols 2g/day
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- University of Valencia
Amputation, Fracture
Bone Physiology & Mechanics in Osteomyoplasty Amputation Rehabilitation
The purpose of the study is to compare the effect of different lower limb amputation surgical procedures on leg bone integrity and rehabilitation outcome.
- Conditions
- Amputation, Fracture, Inflammation, Osteoporosis
- Trial name
- NCT00271362
- Testing
- Amputation rehabilitation exercise program, Osteomyoplasty vs. routine long posterior flap
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- VA Office of Research and Development
Fatigue, Unspecified Adult Solid Tumor, Protocol Specific
Levocarnitine in Treating Fatigue in Cancer Patients
RATIONALE: Levocarnitine may help improve energy levels in cancer patients. PURPOSE: This randomized phase III trial is studying how well levocarnitine works compared to a placebo in treating fatigue in cancer patients.
- Trial name
- NCT00091169
- Testing
- levocarnitine
- Where
- 116 sites in United States
- Volunteers
- 376 people
- Sponsor
- ECOG-ACRIN Cancer Research Group
Urinary Incontinence, Nocturnal Enuresis
Effectiveness of Multimodal Pelvic Floor Rehabilitation Program in Children With Different Types of Urinary Incontinence
Urinary incontinence is defined by the International Children's Continence Society as involuntary urinary leakage that can be continuous or intermittent in children aged five and over.
- Conditions
- Urinary Incontinence, Nocturnal Enuresis, Daytime Wetting, Pelvic Floor Disorders
- Trial name
- NCT06231394
- Testing
- multimodal pelvic floor rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Damla Korkmaz Dayican
Suicide
Suicide Risk Interventions
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan.
- Trial name
- NCT05931289
- Testing
- Enhanced Crisis Response Planning (ECRP), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Binge Eating, Depression
Study of Duloxetine vs Placebo in Treatment of Binge Eating Disorder With Depression
The purpose of this research study is to test the safety of duloxetine and see what effects (good and bad) it has on the subject's binge eating disorder and comorbid depressive disorder (depression occurring with binge eating…
- Trial name
- NCT00607789
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Cincinnati
Anxiety, Pain
A Study of the Impact of a Virtual Reality Medical Device (HypnoVR® Headset) on Anxiety and Pain in Interventional Radiology.
Patients undergoing interventional radiology procedures frequently experience significant anxiety and procedural pain despite standard care.
- Conditions
- Anxiety, Pain, Radiology, Interventional
- Trial name
- HYPNO-VR (NCT07668050)
- Testing
- Immersive Virtual Reality
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Clermont-Ferrand
Overweight, Obesity
Effect of Different Physical Programs on the Body Composition of Adult Men and Women With an Initial Body Fat >25% and >30%, Respectively.
Compare the Effect of Different Physical Programs on the Body Composition of Adult Women and Men With a Total Body Fat Percentage ≥ 30 % at the Beginning of the Test or BMI ≥25
- Trial name
- NCT03833791
- Testing
- education and modifying diet, education, modifying diet and physical activity prescription
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Universidad de Córdoba
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