Clinical trials: Taste Disorder
Appetite and General Nutritional Disorders, Hormone Replacement
Sweet Taste Receptors and the Secretion of Glucagon-like Peptide-1 and Peptide YY
The purpose of this study is to determine the functional significance of sweet taste receptors in the secretion of GI satiety peptides by using a specific sweet taste receptor antagonist to block sweet taste perception in the gut.
- Trial name
- NCT01088841
- Testing
- lactisole
- Where
- Switzerland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
COVID-19
Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)
Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory…
- Trial name
- COVID-OLFA (NCT04407494)
- Testing
- Reporting of anosmia, ageusia and other clinical symptoms
- Where
- France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Genetics, Taste, Altered
Genetics of Bitter and Fat Taste
Obesity is an increasing problem for adults in the UK. Diets high in fat and sugar are the major contributors to weight gain. Individual differences in taste perception are a crucial factor in determining the investigator's…
- Conditions
- Genetics, Taste, Altered, Diet Habit, Obesity
- Trial name
- NCT04038281
- Testing
- Sensory tests
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Obesity
Interactions of Human Gut Microbiota With Intestinal Sweet Taste Receptors
The purpose of this study is to collect data to examine whether short-term consumption of non-caloric artificial sweeteners (NCASs), such as saccharin, can lead to changes in blood sugar levels and in the composition of the…
- Trial name
- ISTAR-micro (NCT03032640)
- Testing
- Oral Glucose Tolerance Test (OGTT), Assessment of dietary compliance, Stool sampling
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Taste, Altered
Flavoring Oral Contrast for MR Enterography
To determine if patient satisfaction, participation, and image quality improves with flavored oral contrast for MR enterography.
- Trial name
- NCT02617576
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Bipolar II Disorder
Differential Responses to Drugs and Sweet Tastes
Young adults who exhibit "bipolar phenotype" (BPP), defined as occasional episodes of mood elevation and heightened activity, are at risk for several psychiatric disorders, including problem use of drugs and alcohol.
- Trial name
- HAP (NCT03810703)
- Testing
- d-amphetamine 10 mg oral capsule, d-amphetamine 20 mg oral capsule
- Where
- 2 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Type 2 Diabetes, Prediabetes
Sweet Sensing in Type 2 Diabetes
Diabetes is a global challenge and the number of people affected by diabetes is expected to rise to 5.5 million by 2030, of which 90% are type 2 diabetes (T2D).
- Trial name
- NCT06804187
- Where
- United Kingdom
- Volunteers
- 505 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Colon Cancer
Pharmacodynamic and Clinical Evaluation of Dose and Taste-optimised Low Volume PEG-based Bowel Cleansing Solutions Using the Split-dosing Intake Regimen in Healthy Subjects and in Subjects Undergoing Screening Colonoscopy
A study to assess the pharmacodynamics, safety and tolerability of a PEG-based bowel cleansing solution (MOVIPREP®)
- Trial name
- NCT01714466
- Testing
- NER1006, MOVIPREP
- Where
- 2 sites in Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Norgine
Oral Complication, Dysgeusia
Oral and Olfactory Complications of Recovered COVID-19 Patients
This cohort study aims to investigate the long-standing chemosensory disorders and oral manifestation after recovery of the COVID-19 illness.
- Conditions
- Oral Complication, Dysgeusia, Olfactory Disorder
- Trial name
- NCT04791436
- Testing
- Gustatory and olfactory function test, Molecular assessment of saliva
- Where
- Germany
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Lichen Planus
Mucosal and Nasal Involvement and Their Correlation With Smell and Taste Functions in Lichen Planus Patients
This study investigates smell and taste function in patients diagnosed with lichen planus, a chronic inflammatory condition affecting the skin and mucous membranes.
- Trial name
- LP-NOSE (NCT07570706)
- Testing
- Grup 1 - Lichen Planus Patients Intervention Name: Taste and Smell Testing, Oral and Nasal Examination, Nasal Endoscopy Intervention Description: Participants undergo taste and smell testing to assess
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Istanbul Training and Research Hospital
Gaucher Disease
Taste Evaluation of Different Liquid Formulations With Eliglustat
Primary Objective: The purpose of this study is to assess the palatability of eliglustat prototype liquid formulations in healthy subjects.
- Trial name
- NCT02422654
- Testing
- eliglustat
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Genzyme, a Sanofi Company
Sodium Excess, Hypertension
Effects of a Six-Day Whole-Diet Intervention on Taste Perception and Dietary Behaviour in Young Adults
This study aims to investigate the effects of a specific diet modification on the pleasantness, desire, and saltiness intensities of selected foods and an ad libitum breakfast buffet through a randomized controlled trial with…
- Conditions
- Sodium Excess, Hypertension, Salty Taste
- Trial name
- NCT07726394
- Testing
- Experimental: Increased Salty Food Intake, Experimental: Decrease Salty Food Intake, Active Comparator: Maintain Usual Diet
- Where
- Malaysia
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Sunway University
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Dysphagia
The Effect of Food Taste, Temperature, and Viscosity on Swallowing Efficiency
The purpose of this study is to evaluate the effect of taste on swallowing efficiency, to evaluate the effect of temperature on swallowing efficiency, and to evaluate the effect of viscosity on swallowing efficiency.
- Trial name
- NCT01270204
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Sjogren's Syndrome
Olfactory and Taste Disturbances in Sjogren's Syndrome
Sjögren syndrome is an autoimmune disease, responsible for xerostomia and xerophthalmia. Other organs and tissues can be affected: the skin, vaginal and nasal mucous membranes.
- Trial name
- TOG_SJOGREN (NCT04909112)
- Testing
- Evaluation of olfactory function, Evaluation of taste function, Evaluation of (intra-nasal and oral) trigeminal functions
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Université de Reims Champagne-Ardenne
Central Visual Impairment, Peripherical Visual Impairment
A Study of Taste- and Olfactory-Evoked Potentials in Patients With Visual Impairment: Taste, Smell, and Vision
Visual impairment, whether central or peripheral, may influence the plasticity of other sensory modalities, such as taste and smell.
- Conditions
- Central Visual Impairment, Peripherical Visual Impairment, Macular Retinal Dystrophy, Peripherical Macular Dystrophy
- Trial name
- GOUSTAVIS (NCT07707219)
- Testing
- Taste and smell evaluation, Recording of evoked potentials (EP)
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Taste Disorders, Sensation Disorders
GOUTMETALSAIN: Comparison of the Perception of Metallic Taste According to Lingual Locations in Healthy Volunteers
This is a mono center , observational study carried out within otorhinolaryngology department in CH Valence. This is a descriptive and exploratory study in healthy volunteers.
- Conditions
- Taste Disorders, Sensation Disorders, Taste, Metallic, Taste Disorder, Glossopharyngeal Nerve
- Trial name
- NCT05227157
- Testing
- swab with iron sulfate solution
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Valence
Cognitive Disorders
Prospective Monocentric Study of Taste in Patients With Minor or Major Cognitive Disorders Such as Alzheimer's, Through the Analysis of Gustatory Evoked Potentials.
Approximately 24 million people worldwide suffer from dementia, with Alzheimer's disease being the most common cause. Alzheimer's disease typically progresses in three stages: presymptomatic, prodromal ("early onset" or minor…
- Trial name
- MAPEG (NCT04860414)
- Testing
- Blood sampling, Cognitive Assessment, Subjective taste tests
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Diabetes, Obesity
A Study of the Function of Hormones Present In Taste Buds
The purpose of this study is to find out whether the hormones in the taste buds are affected by tasting and eating food, and also whether these hormone levels are affected by an increase in body weight or type 2 diabetes.
- Conditions
- Diabetes, Obesity, Pre-Diabetes, Metabolic Syndrome
- Trial name
- NCT00233298
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Obesity
The Obese Taste Bud Study
The sense of taste is essential for priming food preferences and is therefore important for caloric uptake and body weight regulation.
- Trial name
- OTB (NCT04633109)
- Testing
- taste bud biopsy, oral glucose tolerance test, Taste sensitivity
- Where
- Germany
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Leipzig