Clinical trials: Taste Sensitivity
Taste, Non-esterified Fatty Acids
Free Fatty Acids: Threshold Repeatability Study
This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own…
- Trial name
- NCT01550120
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Purdue University
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and ad Libitum Meal Intake
Background Sweet and salty tastes can influence food intake {Sørensen, 2003 #40}. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent…
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- RiceSort (NCT07059117)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Cirrhosis, Food Preferences
Feeding Behavior and Taste Sensitivity Before and After Liver or Renal Transplantation
This study evaluates the influence of the taste sensitivity, of food preferences and of the reward system on the energetic balance before and after liver transplantation in cirrhotic patients and after kidney transplantation in…
- Conditions
- Cirrhosis, Food Preferences, Taste Disorders, Protein-Energy Malnutrition
- Trial name
- GREFFE (NCT02931812)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
Dialysis, Excess Interdialytic Weight Gain
Haemodialysis fMRI Salt Appetite Study
1. Assessing how the rapid removal of salt and water by haemodialysis alters regional brain activity (by measurement of the brain blood oxygen level-dependent (BOLD) signal using functional MRI) during tasting of soup of…
- Trial name
- HeMSA (NCT04011254)
- Testing
- haemodialysis
- Where
- United Kingdom
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma, Croup
Comparison of Dexamethasone Oral Preparations to Assess Taste and Acceptance in Children With Asthma and Croup
Study of the palatability and acceptability of dexamethasone oral tablets crushed and placed in apple sauce or pudding in comparison with the IV solution mixed with sugar syrup and given orally.
- Trial name
- NCT03705273
- Testing
- Dexamethasone IV for PO, Dexamethasone crushed tablets
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
PCOS, Semaglutide
The Effects of Semaglutide on Taste, Tongue Tissue Transcriptome, Gastric Emptying and Central Neural Response in Women With PCOS and Obesity
The purpose of the study is to explore the effects of GLP-1 receptor agonist (GLP-1 RA) semaglutide on modulation of taste sensitivity, tongue tissue transcriptome, modulation of neural response in central reward processing…
- Conditions
- PCOS, Semaglutide, Taste, Altered, Tongue Tissue Transcriptome
- Trial name
- NCT04263415
- Testing
- Semaglutide
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Taste Disorders
Sensitivity of Basic Taste in Elderly
The purpose of this study is to identify the thresholds sensitivity of the five basic tastes in an elderly population and relate to food intake, nutritional status, age, gender and others variables.
- Trial name
- TASTE (NCT03196440)
- Where
- Brazil
- Volunteers
- 280 people
- Sponsor
- Hospital Israelita Albert Einstein
Healthy
Sensitive Periods in Early Flavor Learning
Flavor is the primary dimension by which young children determine food acceptance. However, children are not merely miniature adults since sensory systems mature postnatally and their responses to certain tastes differ markedly…
- Trial name
- NCT00994747
- Testing
- Nutramigen (Flavor and Type of Infant Formula), Enfamil, milk-based formula
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Diabetes, Obesity
A Study of the Function of Hormones Present In Taste Buds
The purpose of this study is to find out whether the hormones in the taste buds are affected by tasting and eating food, and also whether these hormone levels are affected by an increase in body weight or type 2 diabetes.
- Conditions
- Diabetes, Obesity, Pre-Diabetes, Metabolic Syndrome
- Trial name
- NCT00233298
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Dysgeusia
Gustin Gene Polymorphism and 6-n-propylthiouracil (PROP) Taste
The investigators evaluate the possible association of PROP taste with gustin gene polymorphism rs2274333 (A/G), salivary zinc ion concentration and BMI.
- Trial name
- gustinprop (NCT01097915)
- Where
- Italy
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Dysphagia, Stroke
Changes in Sensitivity, Taste and Smell in Stroke Patients
This study evaluates changes in swallowing using endoscopic swallowing studies and measuring of pharyngeal sensitivity, taste and smell in stroke patients.
- Trial name
- 5S (NCT03240965)
- Testing
- FEES (flexible endoscopic evaluation of swallowing), Sensitivity threshold, Taste-/smell-test
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Allergic Rhinitis
Taste Test Between Desloratadine and Cetirizine Syrup in Children (Study P03826)
This study was conducted to compare the taste acceptability of Zyrtec syrup with desloratadine syrup in children. Children between 6 and 11 years of age received 5 mL of each syrup, separated by 15 to 20 minutes on a single day.
- Trial name
- NCT00794794
- Testing
- Desloratadine (Clarinex), Cetirizine (Zyrtec)
- Volunteers
- 204 people
- Sponsor
- Organon and Co
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Smoking
Cough Sensitivity and Taste Preferences
This single-site, within-subject, experimental study is designed to test the hypothesis children who live in a household in which one or both of their parent smoke will exhibit a higher cough threshold and will prefer more…
- Trial name
- CAP (NCT01399060)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Monell Chemical Senses Center
Rhinitis, Allergic, Perennial
Fluticasone Nasal Spray Patient Preference Study
The objectives of this study are to evaluate and compare patient preference for FF (Fluticasone Furoate) and FP (Fluticasone Propionate Aqueous)nasal sprays in the treatment of allergic rhinitis following single-dose…
- Trial name
- NCT00398476
- Testing
- fluticasone propionate (FP), fluticasone furoate (FF)
- Where
- 14 sites in United States
- Volunteers
- 127 people
- Sponsor
- GlaxoSmithKline
Allergic Rhinitis
Taste and Local Tolerance Study of NLA Nasal Spray in Patients With Allergic Rhinitis
Evaluation of NLA Nasal Spray with regard to taste perversion and local tolerance
- Trial name
- NCT00533637
- Testing
- Cetirizine dihydrochloride (10 mg/ml) liposomal formulation, Cetirizine dihydrochloride (10 mg/ml) buffer solution
- Where
- Sweden
- Volunteers
- 28 people
- Sponsor
- Biolipox AB
COVID-19
Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)
Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory…
- Trial name
- COVID-OLFA (NCT04407494)
- Testing
- Reporting of anosmia, ageusia and other clinical symptoms
- Where
- France
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Taste Sensitivity, Fatty Acid Type
Fatty Acid Taste Thresholds: Caproic, Lauric, Oleic, Linoleic, Linolenic
Differences in human oral sensitivity for caproic, lauric, oleic, linoleic, and linolenic acids will be explored. Prior work indicates that there may be a learning effect in measuring detection thresholds for free fatty acids.
- Trial name
- NCT01996566
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Purdue University
Healthy Volunteers
A Study Evaluating Relative Bioavailability of an Oral Suspension of Abrocitinib and Effect of an Acid Reducing Agent on the Bioavailability of Abrocitinib and Assessing the Taste of Abrocitinib Oral Formulations.
This study consists of 2 parts: Part A is to estimate the relative bioavailability of a single 200 mg dose of abrocitinib oral suspension (Test formulation) compared to the commercial abrocitinib tablet (200 mg) (Reference…
- Trial name
- NCT04903093
- Testing
- Abrocitinib tablet, Abrocitinib Suspension F1, Abrocitinib Suspension F2
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Pfizer